Search Results - "Nascimento, Mariane Cristina do"

Pharmacological Inhibition of PIP4K2 Potentiates Venetoclax-Induced Apoptosis in Acute Myeloid Leukemia by Lima, Keli, Carvalho, Maria Fernanda Lopes, Pereira-Martins, Diego Antonio, Nogueira, Frederico Lisboa, de Miranda, Lívia Bassani Lins, Nascimento, Mariane Cristina do, Cavaglieri, Rita de Cássia, Schuringa, Jan Jacob, Machado-Neto, João Agostinho, Rego, Eduardo Magalhães

“…Phosphatidylinositol-5-phosphate 4-kinase type 2 (PIP4K2) protein family members (PIP4K2A, PIP4K2B, and PIP4K2C) participate in the generation of PIP , P ,…”
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PB1826: CELLULAR AND MOLECULAR CHARACTERIZATION OF THE ANTINEOPLASTIC EFFECTS OF CEPHALOCHROMIN IN MODELS OF ACUTE MYELOID LEUKEMIA by Nascimento, Mariane Cristina Do, Pereira‐Martins, Diego A, Alcântara, Guilherme Augusto Sousa, Lima, Keli, Vicari, Hugo Passos, Ferreira, Marcelo José Pena, Costa‐Lotufo, Leticia Leticia Veras, Neto, João Agostinho Machado, Rego, Eduardo Magalhães

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Identification of Vulnerabilities for Pharmacological Inhibition of PIP4K2s in Acute Myeloid Leukemia by Lima, Keli, Carvalho, Maria Fernanda Lopes, Pereira-Martins, Diego A, de Miranda, Lívia Bassani Lins, do Nascimento, Mariane Cristina, Nogueira, Frederico Lisboa, Medeiros, Rita de Cássia Cavaglieri, Schuringa, Jan Jacob, Machado-Neto, João Agostinho, Rego, Eduardo Magalhães

“…Introduction and aims: Proteins of the PIP4K2s family (PIP4K2A, PIP4K2B and PIP4K2C) participate in the generation of PIP 4,5P 2 (PIP 2), which acts as a…”
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Cephalochromin-Induced Mitochondrial Damage Overcomes Venetoclax-Resistance in Acute Myeloid Leukemia Models by Do Nascimento, Mariane Cristina, Pereira-Martins, Diego A, Alcântara, Guilherme Augusto Sousa, Lima, Keli, Vicari, Hugo Passos, Ferreira, Marcelo José Pena, Costa-Lotufo, Leticia Veras, Huls, Gerwin A., Schuringa, Jan Jacob, Machado-Neto, João Agostinho, Rego, Eduardo Magalhães

“…The combination of the BCL2 inhibitor venetoclax (VEN) with hypomethylating agents (e.g. azacytidine, AZA) significantly increased complete remission (CR)…”
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Potency and Efficacy of Pharmacological PIP4K2 Inhibitors in Acute Lymphoblastic Leukemia by Lima, Keli, Carvalho, Maria Fernanda Lopes, Pereira-Martins, Diego A., Silva, Wellington F, do Nascimento, Mariane Cristina, de Miranda, Lívia Bassani Lins, Medeiros, Rita de Cássia Cavaglieri, Nardinelli, Luciana, Leal, Aline de Medeiros, Velloso, Elvira Deolinda Rodrigues Pereira, Bendit, Israel, Schuringa, Jan Jacob, Machado-Neto, João Agostinho, Rego, Eduardo Magalhães

“…Introduction and aims: Adult acute lymphoblastic leukemia (ALL) is a heterogeneous group of highly aggressive hematological malignancies with high recurrence…”
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Reduced SLIT2 Are Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in APL Cells by Weinhäuser, Isabel, Pereira-Martins, Diego A, Simões, Luíse A A, Ortiz Rojas, César Alexander, Bianco, Thiago Mantello, Silva, Cleide Lucia, Do Nascimento, Mariane Cristina, Figueiredo-Pontes, Lorena Lobo, Lucena-Araujo, Antonio R., Rego, Eduardo M

“…Background: Recently, the SLIT/ROBO axis became a therapeutic target for a variety of non-cerebral solid tumors because of its relevance in the regulation of…”
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Data mining in acute myeloid leukemia: identification of disease biomarkers, prognostic factors, novel targets, and potential drugs by Machado-Neto, João Agostinho, do Nascimento, Mariane Cristina, Garnique, Anali Del Milagro Bernabe, Lima, Keli

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Acute myeloid leukemia-derived bone marrow mesenchymal cells exhibit improved support for leukemic cell proliferation by do Nascimento, Mariane Cristina, Pereira-Martins, Diego A, Machado-Neto, João Agostinho, Rego, Eduardo M

“…The bone marrow (BM) microenvironment plays a significant role in acute myeloid leukemia (AML) genesis and there is evidence that BM mesenchymal stromal cells…”
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NSD1 and NSD2 Transcriptional Levels Might Predict Clinical Outcome in AML Patients by De Deus Wagatsuma, Virginia Mara, Pereira-Martins, Diego Antonio, Do Nascimento, Mariane Cristina, Sanchez Mendoza, Silvia Elena, Lucena-Araujo, Antonio R., Lima, Aleide, Saldanha-Araujo, Felipe, Pitella, Fabio, Traina, Fabiola, Madeira, Maria Isabel A, Figueiredo-Pontes, Lorena Lobo, Rego, Eduardo Magalhães

“…Aims: The active methylation of histones plays an important role in regulation of gene expression. Nuclear SET Domain (NSD) Histone Lysine Methyltransferases…”
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The Multikinase Inhibitor AD80 Induces Mitotic Catastrophe and Autophagy in Pancreatic Cancer Cells by Lima, Keli, de Miranda, Lívia Bassani Lins, Del Milagro Bernabe Garnique, Anali, de Almeida, Bruna Oliveira, do Nascimento, Mariane Cristina, Alcântara, Guilherme Augusto Sousa, Machado-Santelli, Glaucia Maria, Rego, Eduardo Magalhães, Machado-Neto, João Agostinho

“…Significant advances in understanding the molecular complexity of the development and progression of pancreatic cancer have been made, but this disease is…”
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Metformintreatment Overcomes ATRA-Resistance in Acute Promyelocytic Leukemia and Increases FOXO3A Expression by Pereira-Martins, Diego Antonio, Ortiz, Cesar, Franca-Neto, Pedro Luis, Weinhäuser, Isabel, Schiavinato, Josiane Lilian, Palma, Patrícia Vianna Bonini, Bonaldo, Camila, Koury, Luisa C A, Do Nascimento, Mariane Cristina, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B B, Pasquini, Ricardo, Fagundes, Evandro Maranhão, Gloria, Ana Beatriz F., Kerbauy, Fabio R., Chauffaille, Maria de Lourdes, Keating, Armand, Tallman, Martin S., Ribeiro, Raul, Dillon, Richard, Ganser, Arnold, Lowenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Lucena-Araujo, Antonio R., Rego, Eduardo Magalhães

“…Introduction:FOXO3A is a transcription factor shown to be involved in all-trans retinoic acid (ATRA)-induced granulocytic differentiation and apoptosis in…”
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