Search Results - "Nascimento, Maria Fernanda Alves do"
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A Comprehensive View on (−)‐7‐Oxo‐ent‐kaur‐16‐en‐19‐oic Acid, the Major Constituent of Xylopia sericea Leaves Extract: Complete NMR Assignments, X‐Ray Crystallographic Structure, in Vitro Antimalarial Activity and Cytotoxicity
Published in Chemistry & biodiversity (01-07-2019)“…Bioguided fractionation of Xylopia sericea antiplasmodial dichloromethane leaves extract led to the isolation of (−)‐7‐oxo‐ent‐kaur‐16‐en‐19‐oic acid…”
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Quinolinotriazole antiplasmodials via click chemistry: synthesis and in vitro studies of 7-Chloroquinoline-based compounds
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2021)“…Malaria is nowadays one of the most serious health concerns in a global scale and, although there is an evident increase in research studies in this area,…”
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Synthesis, SAR, and Docking Studies Disclose 2-Arylfuran-1,4-naphthoquinones as In Vitro Antiplasmodial Hits
Published in Journal of tropical medicine (01-01-2017)“…A total of 28 lapachol-related naphthoquinones with four different scaffolds were synthesized and spectroscopically characterized. In vitro antiplasmodial…”
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Antiplasmodial activity and cytotoxicity, isolation of active alkaloids, and dereplication of Xylopia sericea leaves ethanol extract by UPLC‐DAD‐ESI‐MS/MS
Published in Journal of pharmacy and pharmacology (01-02-2019)“…Objectives To assess the antiplasmodial activity of the ethanol extract of Xylopia sericea leaves, Annonaceae, often associated with antimalarial use and to…”
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In Vitro and in Vivo Antimalarial Activity, Cytotoxicity and Phytochemical HRMS2 Profile of Plants from the Western Pará State, Brazilian Amazonia
Published in Chemistry & biodiversity (01-01-2024)“…Ethnopharmacology and botanical taxonomy are valid criteria used to selecting plants for antimalarial bioprospection purposes. Based on these two criteria,…”
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Phytochemistry and antiplasmodial activity of Xylopia sericea leaves
Published in Natural product research (16-12-2020)“…Aiming to investigate the antiplasmodial activity and the phytochemical composition of Xylopia sericea leaves, the essential oil and dichloromethane extract…”
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Bioprospection for antiplasmodial activity, and identification of bioactive metabolites of native plants species from the Mata Atlântica biome, Brazil
Published in Natural product research (19-05-2021)“…A total of 33 extracts of eleven different plants species from Mata Atlântica biome, Brazil, and different fractions of the bioactive extracts were evaluated…”
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Triterpenes from Minquartia guianensis (Olacaceae) and in vitro antimalarial activity
Published in Química Nova (2012)“…Minquartia guianensis, popularly known as acariquara, was phytochemically investigated. The following triterpenes were isolated from the dichloromethane…”
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In silico, in vitro and in vivo evaluation of natural Bignoniaceous naphthoquinones in comparison with atovaquone targeting the selection of potential antimalarial candidates
Published in Toxicology and applied pharmacology (15-08-2020)“…The natural naphthoquinones lapachol, α- and β-lapachone are found in Bignoniaceous Brazilian plant species of the Tabebuia genus (synonym Handroanthus) and…”
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In vitro antiplasmodial activity and identification, using tandem LC-MS, of alkaloids from Aspidosperma excelsum, a plant used to treat malaria in Amazonia
Published in Journal of ethnopharmacology (10-01-2019)“…Aspidosperma excelsum Benth. (Apocynaceae), a native tree in the Brazilian Amazonia, is traditionally used to treat various diseases, including malaria. To…”
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In vitro antiplasmodial activity, targeted LC–MS metabolite profiling, and identification of major natural products in the bioactive extracts of Palicourea and Psychotria species from the Amazonia and Atlantic Forest biomes, Brazil
Published in Metabolomics (01-09-2021)“…Introduction A great variety of bioactive natural products has been reported for different Palicourea and Psychotria species (Rubiaceae). However, few of them…”
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SPLEEN CELL PROLIFERATION DURING AND AFTER SKIN MYIASIS BY HUMAN BOT FLY Dermatobia hominis
Published in Revista do Instituto de Medicina Tropical de São Paulo (01-05-2009)“…Spleen cells from mice were examined at 5, 10, 15, 20 and 25 days post-infection (dpi) with Dermatobia hominis larva and at 5, 10, 15, 30 and 60 days…”
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Antiplasmodial and cytotoxic effects of the methanol extract, canthinone alkaloids, squalene- and protolimonoid-type triterpenes from Homalolepis suffruticosa roots
Published in Journal of ethnopharmacology (01-03-2022)“…Different species of the Simaroubaceae family are used in traditional medicine to treat malaria. Among these is Homalolepis suffruticosa (syn. Simaba…”
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In Vitro and in Vivo Antimalarial Activity, Cytotoxicity and Phytochemical HRMS 2 Profile of Plants from the Western Pará State, Brazilian Amazonia
Published in Chemistry & biodiversity (01-01-2024)“…Ethnopharmacology and botanical taxonomy are valid criteria used to selecting plants for antimalarial bioprospection purposes. Based on these two criteria,…”
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Antimalarial Activity of Zincke’s Salts
Published in Journal of biological sciences (Faisalabad, Pakistan) (2013)“…A series of Zincke's salts was synthesized from new pyridine precursors and evaluated for their antiplasmodial and cytotoxicity activity. The Zincke's salts…”
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Spleen cell proliferation during and after skin myiasis by human bot fly Dermatobia hominis Proliferação de células do baço durante e após miíase por Dermatobia hominis
Published in Revista do Instituto de Medicina Tropical de São Paulo (01-06-2009)“…Spleen cells from mice were examined at 5, 10, 15, 20 and 25 days post-infection (dpi) with Dermatobia hominis larva and at 5, 10, 15, 30 and 60 days…”
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