PAPEL DO MICROAMBIENTE TUMORAL NO DESENVOLVIMENTO DO MELANOMA

The last ten years, the incidence of cancer has been globally alarming constituting a serious public health problem with increasing expectations for the coming decades. Epidemiological studies in Brazil showed that, the most prevalent of all cancers is prostate cancer, however skin cancer has impact...

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Bibliographic Details
Published in:	Veterinária Notícias Vol. 21; no. 2; pp. 1 - 49
Main Authors:	Carvalho, José Renildo, Nascimento, Edilaine Sudré Marcelino, Xavier, José Guilherme, Banamin, Leoni Villano, Hurtado, Elizabeth Cristina Perez
Format:	Journal Article
Language:	English
Published:	EDUFU 21-09-2015
Subjects:	Cytokines Macrophages Melanoma T and B lymphocytes Tumoral microenvironment
Online Access:	Get full text
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Summary:	The last ten years, the incidence of cancer has been globally alarming constituting a serious public health problem with increasing expectations for the coming decades. Epidemiological studies in Brazil showed that, the most prevalent of all cancers is prostate cancer, however skin cancer has impacted significantly the general population. Among the main types of skin cancer, melanoma causes more deaths due to its high ability to metastasize. Several factors are involved in the development of melanoma, however interactions between the neoplastic cells and the normal cells at the site where the tumor develops is the aim of many research centers in cancer. Thus, this review presents the main findings described in the last ten years in relation to the interactions between cancer cells and the components of the tumor microenvironment in melanoma model.
ISSN:	1983-0777 1983-0777
DOI:	10.14393/VTv21n2a2015.29673