Search Results - "Narvaiz, David A."

Lipopolysaccharide‐induced sickness behavior is not altered in male Fmr1‐deficient mice by Santana‐Coelho, Danielle, Hodges, Samantha L., Quintero, Saul I., Womble, Paige D., Sullens, D. Greg, Narvaiz, David A., Herrera, Rebecca, Sekeres, Melanie J., Lugo, Joaquin N.

“…Objectives Fragile X syndrome is the main monogenetic cause of intellectual disability and autism. Alterations in the immune system are commonly found in these…”
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A Two-Hit Approach Inducing Flurothyl Seizures in Fmr1 Knockout Mice Impacts Anxiety and Repetitive Behaviors by Blandin, Katherine J, Narvaiz, David A, Sullens, Donald Gregory, Womble, Paige D, Hodges, Samantha L, Binder, Matthew S, Faust, Amanda, Nguyen, Phuoc H, Pranske, Zachary J, Lugo, Joaquin N

“…Fragile X Syndrome (FXS) is the leading monogenetic cause of autism spectrum disorder (ASD) and is associated with seizures. We examined the impact of repeated…”
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Neuronal subset-specific phosphatase and tensin homolog knockout mice exhibit age and brain region-associated alterations in microglia/macrophage activation by Narvaiz, David A., Sullens, D. Gregory, Santana-Coelho, Danielle, Lugo, Joaquin N.

“…Seizures induce brain region-dependent enhancements in microglia/macrophage activation. Neuronal subset–specific phosphatase and tensin homolog (PTEN) knockout…”
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NS-Pten knockout mice exhibit sex and hippocampal subregion-specific increases in microglia/macrophage density by Narvaiz, David A., Blandin, Katherine J., Sullens, D. Gregory, Womble, Paige D., Pilcher, Jacob B., O’Neill, Grace, Wiley, Taylor A., Kwok, Eliesse M., Chilukuri, Srikhar V., Lugo, Joaquin N.

“…Seizures induce hippocampal subregion dependent enhancements in microglia/macrophage phagocytosis and cytokine release that may contribute to the development…”
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Agomelatine Is Unable to Attenuate Kainic Acid–Induced Deficits in Early Life Communicative Behavior by Binder, Matthew S., Pranske, Zachary J., Hodges, Samantha L., Womble, Paige D., Kwok, Eliesse M., Quintero, Saul I., Kim, Andrew D., Narvaiz, David A., Lugo, Joaquin N.

“…ABSTRACT Early life seizures are associated with a variety of behavioral comorbidities. Among the most prevalent of these are deficits in communication…”
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Neonatal immune stimulation results in sex‐specific changes in ultrasonic vocalizations but does not affect seizure susceptibility in neonatal mice by Santana‐Coelho, Danielle, Pranske, Zachary J., Nolan, Suzanne O., Hodges, Samantha L., Binder, Matthew S., Womble, Paige D., Narvaiz, David A., Muhammad, Ilyasah, Lugo, Joaquin N.

“…Neuroinflammation during the neonatal period has been linked to disorders such as autism and epilepsy. In this study, we investigated the early life behavioral…”
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Rapamycin improves social and stereotypic behavior abnormalities induced by pre‐mitotic neuronal subset specific Pten deletion by Narvaiz, David A., Nolan, Suzanne O., Smith, Gregory D., Holley, Andrew J., Reynolds, Conner D., Blandin, Katherine J., Nguyen, Phuoc H., Tran, Doan L. K., Lugo, Joaquin N.

“…The mechanistic target of rapamycin (mTOR) pathway is a signaling system integral to neural growth and migration. In both patients and rodent models, mutations…”
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Vitamin D supplementation positively affects activity but impairs stimulus response behavior in an age and sex specific manner in C57BL/6 mice by Narvaiz, David A., Kwok, Eliesse M., Hodges, Samantha L., Binder, Matthew S., Nolan, Suzanne O., Pranske, Zachary J., Senger, Savannah, Herrera, Rebecca, Lugo, Joaquin N.

“…Several studies have begun to demonstrate the possible cognitive and physiological benefits of a fortified vitamin D diet. However, the behavioral effects of a…”
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A flurothyl-induced seizure does not disrupt hippocampal memory reconsolidation in C57BL/6 J mice by Binder, Matthew S., Prankse, Zachary J., Kim, Andrew D., Hodges, Samantha L., Narvaiz, David A., Womble, Paige D., Lugo, Joaquin N.

“…Memory deficits are a prevalent and pervasive comorbidity of epilepsy that significantly decrease an individual’s quality of life. Numerous studies have…”
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Multiple Early-Life Seizures Alters Neonatal Communicative Behavior in Fmr1 Knockout Mice by Nguyen, Phuoc H, Narvaiz, David A, Womble, Paige D, Sullens, D Gregory, Binder, Matthew S, Hodges, Samantha L, Kwok, Eliesse, Lugo, Joaquin N

“…Fragile X syndrome (FXS) is the leading monogenic cause of intellectual disability and a significant contributor to Autism Spectrum Disorder. Individuals with…”
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Neuronal subset-specific phosphatase and tensin homolog knockout mice exhibit age and brain region-associated alterations in microglia/macrophage activation by Narvaiz, David A., Sullens, D. Gregory, Santana-Coelho, Danielle, Lugo, Joaquin N.

“…Seizures induce brain region-dependent enhancements in microglia/macrophage activation. Neuronal subset–specific phosphatase and tensin homolog ( PTEN )…”
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NS-PTEN Knockout Mice Exhibit Age and Brain Region Associated Alterations in MHC-II Specific Microglia/Macrophage Activation by Narvaiz, David A., Sullens, D. Gregory, Santana-Coelho, Danielle, Lugo, Joaquin N.

“…Seizures induce brain region dependent enhancements in microglia/macrophage activation. Neuronal subset specific phosphatase and tensin gene deleted on…”
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