Search Results - "Naruoka, Haruna"

Therapeutic Effects of MicroRNA-582-5p and -3p on the Inhibition of Bladder Cancer Progression by Uchino, Keita, Takeshita, Fumitaka, Takahashi, Ryou-u, Kosaka, Nobuyoshi, Fujiwara, Kae, Naruoka, Haruna, Sonoke, Satoru, Yano, Junichi, Sasaki, Hideo, Nozawa, Shiari, Yoshiike, Miki, Kitajima, Kazuki, Chikaraishi, Tatsuya, Ochiya, Takahiro

“…Many reports have indicated that the abnormal expression of microRNAs (miRNAs) is associated with the progression of disease and have identified miRNAs as…”
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NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia by Kimura, Shinya, Naito, Haruna, Segawa, Hidekazu, Kuroda, Junya, Yuasa, Takeshi, Sato, Kiyoshi, Yokota, Asumi, Kamitsuji, Yuri, Kawata, Eri, Ashihara, Eishi, Nakaya, Yohei, Naruoka, Haruna, Wakayama, Tatsushi, Nasu, Kimio, Asaki, Tetsuo, Niwa, Tomoko, Hirabayashi, Kazuko, Maekawa, Taira

“…Although the Abelson (Abl) tyrosine kinase inhibitor imatinib mesylate has improved the treatment of breakpoint cluster region–Abl (Bcr-Abl)–positive leukemia,…”
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Analyses of mitogen-activated protein kinase function in the maturation of porcine oocytes by Ohashi, S, Naito, K, Sugiura, K, Iwamori, N, Goto, S, Naruoka, H, Tojo, H

“…The function of mitogen-activated protein kinase (MAPK) during porcine oocyte maturation was examined by injecting oocytes with either mRNA or antisense RNA of…”
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Effects of spindle removal on MPF and MAP kinase activities in porcine matured oocytes by Goto, Seitaro, Naito, Kunihiko, Ohashi, Satoshi, Sugiura, Koji, Naruoka, Haruna, Iwamori, Naoki, Tojo, Hideaki

“…Intracellular localization of maturation/M‐phase promoting factor (MPF) and mitogen activated protein (MAP) kinase in mature oocytes has been examined by…”
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Antiproliferative and Antitumor Effects of Azacitidine Against the Human Myelodysplastic Syndrome Cell Line SKM-1 by KIMURA, Sachie, KURAMOTO, Kazuya, HOMAN, Junko, NARUOKA, Haruna, EGO, Takeshi, NOGAWA, Masaki, SUGAHARA, Seishi, NAITO, Haruna

“…The myelodysplastic syndromes (MDS) are a group of stem cell disorders characterized by dysplasia of one or more hematopoietic cell lineages and a risk of…”
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Synthesis, gene-silencing activity and nuclease resistance of 3′–3′-linked double short hairpin RNA by Masuda, Hirofumi, Watanabe, Naoki, Naruoka, Haruna, Nagata, Seigo, Takagaki, Kazuchika, Wada, Takeshi, Yano, Junichi

“…Short hairpin RNAs linked at their 3′ ends by glycerol show structure-dependent gene-silencing activity as well as higher exonuclease resistance and lower…”
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In vivo antiproliferative effect of NS-187, a dual Bcr-Abl/Lyn tyrosine kinase inhibitor, on leukemic cells harbouring Abl kinase domain mutations by Naito, Haruna, Kimura, Shinya, Nakaya, Yohei, Naruoka, Haruna, Kimura, Sachie, Ito, Shinsaku, Wakayama, Tatsushi, Maekawa, Taira, Hirabayashi, Kazuko

“…Advanced-phase chronic myeloid leukemia patients treated with imatinib often relapse due to point mutations in the Abl kinase domain. We herein examine the in…”
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Simultaneous Targeting of Lyn and Bcr-Abl Kinases by NS-187 Cures Mice Bearing Imatinib-Resistant Leukemic Cells by Naito, Haruna, Kimura, Shinya, Nakaya, Yohei, Naruoka, Haruna, Wakayama, Tatsushi, Kimura, Sachie, Ito, Shinsaku, Ashihara, Eishi, Maekawa, Taira, Hirabayashi, Kazuko

“…We have identified a specific dual Bcr-Abl/Lyn inhibitor, NS-187 (elsewhere described as CNS-9), which is 25–55 times more potent than imatinib against wild…”
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A Dual Bcr-Abl/Lyn Tyrosine Kinase Inhibitor, NS-187, Is a Novel Agent for Imatinib-Resistant Leukemia by Kimura, Shinya, Naito, Haruna, Yokota, Asumi, Kamitsuji, Yuri, Kawata, Eri, Ashihara, Eishi, Nakaya, Yohei, Naruoka, Haruna, Wakayama, Tatsushi, Asaki, Tetsuo, Niwa, Tomoko, Hirabayashi, Kazuko, Maekawa, Taira

“…Chemical modifications of imatinib mesylate made with the guidance of molecular modeling yielded several promising compounds. Among them, we selected a…”
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Analyses of Mitogen-Activated Protein Kinase Function in the Maturation of Porcine Oocytes1 by Ohashi, Satoshi, Naito, Kunihiko, Sugiura, Koji, Iwamori, Naoki, Goto, Seitaro, Naruoka, Haruna, Tojo, Hideaki

“…The function of mitogen-activated protein kinase (MAPK) during porcine oocyte maturation was examined by injecting oocytes with either mRNA or antisense RNA of…”
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