Search Results - "Narumi, Rika"
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1
Src-transformed cells hijack mitosis to extrude from the epithelium
Published in Nature communications (08-11-2018)“…At the initial stage of carcinogenesis single mutated cells appear within an epithelium. Mammalian in vitro experiments show that potentially cancerous cells…”
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2
MDCK cells expressing constitutively active Yes-associated protein (YAP) undergo apical extrusion depending on neighboring cell status
Published in Scientific reports (21-06-2016)“…Cell competition is a cell-cell interaction by which a cell compares its fitness to that of neighboring cells. The cell with the relatively lower fitness level…”
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3
Chemical-Induced Cleft Palate Is Caused and Rescued by Pharmacological Modulation of the Canonical Wnt Signaling Pathway in a Zebrafish Model
Published in Frontiers in cell and developmental biology (14-12-2020)“…Cleft palate is one of the most frequent birth defects worldwide. It causes severe problems regarding eating and speaking and requires long-term treatment…”
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4
Strain difference of cadmium-induced testicular toxicity in inbred Wistar-Imamichi and Fischer 344 rats
Published in Archives of toxicology (01-07-2009)“…Previously, we reported that Wistar-Imamichi (WI) rats are highly resistant to cadmium (Cd)-induced lethality and hepatotoxicity compared to Fischer 344 (F344)…”
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5
Chemical‐induced craniofacial anomalies caused by disruption of neural crest cell development in a zebrafish model
Published in Developmental dynamics (01-07-2020)“…Background Craniofacial anomalies are among the most frequent birth defects worldwide, and are thought to be caused by gene‐environment interactions…”
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Concentrations and Distribution of Mercury and Other Heavy Metals in Surface Sediments of the Yatsushiro Sea including Minamata Bay, Japan
Published in Bulletin of environmental contamination and toxicology (01-01-2008)“…The concentrations and distribution of heavy metals, such as mercury, zinc, copper, lead, and iron in surface sediments from 234 stations of the Yatsushiro Sea…”
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7
Sequential oncogenic mutations influence cell competition
Published in Current biology (27-09-2021)“…At the initial stage of carcinogenesis, newly emerging transformed cells are often eliminated from epithelial layers via cell competition with the surrounding…”
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8
Calcium Wave Promotes Cell Extrusion
Published in Current biology (24-02-2020)“…When oncogenic transformation or apoptosis occurs within epithelia, the harmful or dead cells are apically extruded from tissues to maintain epithelial…”
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Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes
Published in Nature cell biology (01-05-2017)“…Recent studies have revealed that newly emerging transformed cells are often apically extruded from epithelial tissues. During this process, normal epithelial…”
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Expression analysis of genes including Zfhx4 in mice and zebrafish reveals a temporospatial conserved molecular basis underlying craniofacial development
Published in Developmental dynamics (25-09-2024)“…Embryonic craniofacial development involves several cellular and molecular events that are evolutionarily conserved among vertebrates. Vertebrate models such…”
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11
Inhibition of carbonyl reductase activity in pig heart by alkyl phenyl ketones
Published in Journal of enzyme inhibition and medicinal chemistry (01-02-2007)“…The inhibitory effects of alkyl phenyl ketones on carbonyl reductase activity were examined in pig heart. In this study, carbonyl reductase activity was…”
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