Search Results - "Narta, Kiran"

Spatiotemporal modeling reveals high-resolution invasion states in glioblastoma by Manoharan, Varsha Thoppey, Abdelkareem, Aly, Gill, Gurveer, Brown, Samuel, Gillmor, Aaron, Hall, Courtney, Seo, Heewon, Narta, Kiran, Grewal, Sean, Dang, Ngoc Ha, Ahn, Bo Young, Osz, Kata, Lun, Xueqing, Mah, Laura, Zemp, Franz, Mahoney, Douglas, Senger, Donna L, Chan, Jennifer A, Morrissy, A Sorana

“…Diffuse invasion of glioblastoma cells through normal brain tissue is a key contributor to tumor aggressiveness, resistance to conventional therapies, and…”
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Fusion transcripts in normal human cortex increase with age and show distinct genomic features for single cells and tissues by Mehani, Bharati, Narta, Kiran, Paul, Deepanjan, Raj, Anurag, Kumar, Deepak, Sharma, Anchal, Kaurani, Lalit, Nayak, Subhashree, Dash, Debasis, Suri, Ashish, Sarkar, Chitra, Mukhopadhyay, Arijit

“…Fusion transcripts can contribute to diversity of molecular networks in the human cortex. In this study, we explored the occurrence of fusion transcripts in…”
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EPCO-51. FUNCTIONAL ANALYSIS OF REGULATORY MUTATIONS IN PEDIATRIC BRAIN TUMORS by Narta, Kiran, Verhey, Theodore, Manoharan, Varsha Thoppey, Morrissy, Sorana

“…Abstract Pediatric brain tumors are the primary cause of cancer related mortality in children and are characterized by low mutations burden. The known somatic…”
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ANGI-05. UNSUPERVISED DECONVOLUTION OF SPATIOTEMPORAL HETEROGENEITY REVEALS HIGH-RESOLUTION INVASION STATES IN GLIOBLASTOMA by Manoharan, Varsha Thoppey, Abdelkareem, Aly, Brown, Samuel, Gillmor, Aaron, Hall, Courtney, Seo, Heewon, Narta, Kiran, Grewal, Sean, Dang, Ngoc Ha, Ahn, Bo Young, Osz, Kata, Lun, Xueqing, Mahoney, Douglas, Senger, Donna, Chan, Jennifer, Morrissy, Sorana

“…Abstract Diffuse invasion of glioblastoma cells through normal brain tissue is a key contributor to tumor aggressiveness, resistance to conventional therapies,…”
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Whole-Exome Sequencing of Vitiligo Lesions Indicates Lower Burden of Somatic Variations: Implications in Risk for Nonmelanoma Skin Cancers by Gupta, Iti, Shankrit, Shambhavi, Narta, Kiran, Ghazi, Madeeha, Grover, Ritika, Pandey, Rajesh, Kar, Hemanta Kumar, Menon, Shruti M., Gupta, Aayush, Yenamandra, Vamsi K., Singh, Archana, Mukerji, Mitali, Mukhopadhyay, Arijit, Rani, Rajni, Gokhale, Rajesh S., Dash, Debasis, Natarajan, Vivek T.

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Novel internal regulators and candidate miRNAs within miR-379/miR-656 miRNA cluster can alter cellular phenotype of human glioblastoma by Nayak, Subhashree, Aich, Meghali, Kumar, Anupam, Sengupta, Suman, Bajad, Prajakta, Dhapola, Parashar, Paul, Deepanjan, Narta, Kiran, Purkrait, Suvendu, Mehani, Bharati, Suri, Ashish, Chakraborty, Debojyoti, Mukhopadhyay, Arijit, Sarkar, Chitra

“…Clustered miRNAs can affect functioning of downstream pathways due to possible coordinated function. We observed 78–88% of the miR-379/miR-656 cluster (C14MC)…”
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Myg1 exonuclease couples the nuclear and mitochondrial translational programs through RNA processing by Grover, Ritika, Burse, Shaunak A, Shankrit, Shambhavi, Aggarwal, Ayush, Kirty, Kritika, Narta, Kiran, Srivastav, Rajpal, Ray, Ashwini Kumar, Malik, Garima, Vats, Archana, Motiani, Rajender K, Thukral, Lipi, Roy, Soumya Sinha, Bhattacharya, Sudha, Sharma, Rakesh, Natarajan, Krishnamurthy, Mukerji, Mitali, Pandey, Rajesh, Gokhale, Rajesh S, Natarajan, Vivek T

“…Semi-autonomous functioning of mitochondria in eukaryotic cell necessitates coordination with nucleus. Several RNA species fine-tune mitochondrial processes by…”
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Abstract PR-011: The role of tumor microenvironment in metastasis and relapses of medulloblastoma using immunocompetent mouse models by Khazaei, Niusha, Orozco, Ana Castillo, Jawhar, Wajih, Danieau, Geoffroy, Narta, Kiran, Taylor, Michael, Morrissy, Sorana, Stuecklin, Ana, Garzia, Livia

“…Abstract Medulloblastoma (MB) is an embryonal malignant tumor that arises in the cerebellum of infants, children, and adolescents. Despite highly aggressive…”
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Intratumoral Genetic and Functional Heterogeneity in Pediatric Glioblastoma by Hoffman, Mary, Gillmor, Aaron H, Kunz, Daniel J, Johnston, Michael J, Nikolic, Ana, Narta, Kiran, Zarrei, Mehdi, King, Jennifer, Ellestad, Katrina, Dang, Ngoc Ha, Cavalli, Florence M G, Kushida, Michelle M, Coutinho, Fiona J, Zhu, Yuankun, Luu, Betty, Ma, Yussanne, Mungall, Andrew J, Moore, Richard, Marra, Marco A, Taylor, Michael D, Pugh, Trevor J, Dirks, Peter B, Strother, Douglas, Lafay-Cousin, Lucie, Resnick, Adam C, Scherer, Stephen, Senger, Donna L, Simons, Benjamin D, Chan, Jennifer A, Morrissy, A Sorana, Gallo, Marco

“…Pediatric glioblastoma (pGBM) is a lethal cancer with no effective therapies. To understand the mechanisms of tumor evolution in this cancer, we performed…”
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Whole Exome Sequencing Reveals Novel Candidate Genes in Familial Forms of Glaucomatous Neurodegeneration by Narta, Kiran, Teltumbade, Manoj Ramesh, Vishal, Mansi, Sadaf, Samreen, Faruq, Mohd, Jama, Hodan, Waseem, Naushin, Rao, Aparna, Sen, Abhijit, Ray, Kunal, Mukhopadhyay, Arijit

“…Glaucoma is the largest cause of irreversible blindness with a multifactorial genetic etiology. This study explores novel genes and gene networks in familial…”
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Genetic association and stress mediated down-regulation in trabecular meshwork implicates MPP7 as a novel candidate gene in primary open angle glaucoma by Vishal, Mansi, Sharma, Anchal, Kaurani, Lalit, Alfano, Giovanna, Mookherjee, Suddhasil, Narta, Kiran, Agrawal, Jyoti, Bhattacharya, Iman, Roychoudhury, Susanta, Ray, Jharna, Waseem, Naushin H, Bhattacharya, Shomi S, Basu, Analabha, Sen, Abhijit, Ray, Kunal, Mukhopadhyay, Arijit

“…Glaucoma is the largest cause of irreversible blindness affecting more than 60 million people globally. The disease is defined as a gradual loss of peripheral…”
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