Search Results - "Narreddula, Venkateswara R."

Apocryphal FADS2 activity promotes fatty acid diversification in cancer by Young, Reuben S.E., Bowman, Andrew P., Williams, Elizabeth D., Tousignant, Kaylyn D., Bidgood, Charles L., Narreddula, Venkateswara R., Gupta, Rajesh, Marshall, David L., Poad, Berwyck L.J., Nelson, Colleen C., Ellis, Shane R., Heeren, Ron M.A., Sadowski, Martin C., Blanksby, Stephen J.

“…Canonical fatty acid metabolism describes specific enzyme-substrate interactions that result in products with well-defined chain lengths, degree(s), and…”
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Mass spectrometry-directed structure elucidation and total synthesis of ultra-long chain (O-acyl)-ω-hydroxy fatty acids by Hancock, Sarah E., Ailuri, Ramesh, Marshall, David L., Brown, SimonH.J., Saville, Jennifer T., Narreddula, Venkateswara R., Boase, Nathan R., Poad, BerwyckL.J., Trevitt, Adam J., Willcox, MarkD.P., Kelso, Michael J., Mitchell, Todd W., Blanksby, Stephen J.

“…The (O-acyl)-ω-hydroxy FAs (OAHFAs) comprise an unusual lipid subclass present in the skin, vernix caseosa, and meibomian gland secretions. Although they are…”
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Identification of Carbon-Carbon Double Bond Stereochemistry in Unsaturated Fatty Acids by Charge-Remote Fragmentation of Fixed-Charge Derivatives by Young, Reuben S. E., Flakelar, Clare L., Narreddula, Venkateswara R., Jekimovs, Lachlan J., Menzel, Jan P., Poad, Berwyck L. J., Blanksby, Stephen J.

“…Separation and identification of fatty acid (FA) isomers in biological samples represents a challenging problem for lipid chemists. Notably, FA regio- and…”
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Introduction of a Fixed-Charge, Photolabile Derivative for Enhanced Structural Elucidation of Fatty Acids by Narreddula, Venkateswara R, Boase, Nathan R, Ailuri, Ramesh, Marshall, David L, Poad, Berwyck L.J, Kelso, Michael J, Trevitt, Adam J, Mitchell, Todd W, Blanksby, Stephen J

“…Fatty acids are a structurally diverse category of lipids with a myriad of biochemical functions, which includes their role as building blocks of more complex…”
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Next-generation derivatization reagents optimized for enhanced product ion formation in photodissociation-mass spectrometry of fatty acids by Narreddula, Venkateswara R, McKinnon, Benjamin I, Marlton, Samuel J P, Marshall, David L, Boase, Nathan R B, Poad, Berwyck L J, Trevitt, Adam J, Mitchell, Todd W, Blanksby, Stephen J

“…Ultraviolet-photodissociation (UVPD) mass spectrometry is an emerging analytical tool for structural elucidation of biomolecules including lipids. Gas phase…”
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Establishing carbon-carbon double bond position and configuration in unsaturated fatty acids by gas-phase infrared spectroscopy by Kirschbaum, Carla, Young, Reuben S. E, Greis, Kim, Menzel, Jan Philipp, Gewinner, Sandy, Schöllkopf, Wieland, Meijer, Gerard, von Helden, Gert, Causon, Tim, Narreddula, Venkateswara R, Poad, Berwyck L. J, Blanksby, Stephen J, Pagel, Kevin

“…Fatty acids are an abundant class of lipids that are characterised by wide structural variation including isomeric diversity arising from the position and…”
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Structural elucidation of hydroxy fatty acids by photodissociation mass spectrometry with photolabile derivatives by Narreddula, Venkateswara R., Sadowski, Pawel, Boase, Nathan R.B., Marshall, David L., Poad, Berwyck L.J., Trevitt, Adam J., Mitchell, Todd W., Blanksby, Stephen J.

“…Rationale Eicosanoids are short‐lived bio‐responsive lipids produced locally from oxidation of polyunsaturated fatty acids (FAs) via a cascade of enzymatic or…”
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Combining Charge-Switch Derivatization with Ozone-Induced Dissociation for Fatty Acid Analysis by Poad, Berwyck L. J., Marshall, David L., Harazim, Eva, Gupta, Rajesh, Narreddula, Venkateswara R., Young, Reuben S. E., Duchoslav, Eva, Campbell, J. Larry, Broadbent, James A., Cvačka, Josef, Mitchell, Todd W., Blanksby, Stephen J.

“…The specific positions of carbon–carbon double bond(s) within an unsaturated fatty acid exert a significant effect on the physical and chemical properties of…”
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Comparing Positively and Negatively Charged Distonic Radical Ions in Phenylperoxyl Forming Reactions by Williams, Peggy E., Marshall, David L., Poad, Berwyck L. J., Narreddula, Venkateswara R., Kirk, Benjamin B., Trevitt, Adam J., Blanksby, Stephen J.

“…In the gas phase, arylperoxyl forming reactions play a significant role in low-temperature combustion and atmospheric processing of volatile organic compounds…”
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Combining Charge-Switch Derivatization with Ozone-Induced Dissociation for Fatty Acid Analysis by Poad, Berwyck L J, Marshall, David L, Harazim, Eva, Gupta, Rajesh, Narreddula, Venkateswara R, Young, Reuben S E, Duchoslav, Eva, Campbell, J Larry, Broadbent, James A, Cvačka, Josef, Mitchell, Todd W, Blanksby, Stephen J

“…The specific positions of carbon-carbon double bond(s) within an unsaturated fatty acid exert a significant effect on the physical and chemical properties of…”
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An efficient synthesis of (7S,10R)-2-bromo-5,6,7,8,9,10-hexahydro-7,10-epiminocyclohepta[b]indole: application in the preparation and structural confirmation of a potent 5-HT6 antagonist by Isherwood, Matthew L., Guzzo, Peter R., Henderson, Alan J., Hsia, Ming Min, Kaur, Jagjit, Nacro, Kassoum, Narreddula, Venkateswara R., Panduga, Shailaja, Pathak, Rashmi, Shimpukade, Bharat, Tan, Valentina, Xiang, Kai, Qiang, Zhu, Ghosh, Animesh

“…(7S,10R)-5-Methyl-2-((3-(trifluoromethyl)phenyl)sulfonyl)-5,6,7,8,9,10-hexahydro-7,10-epiminocyclohepta[b]indole 1a is a potent 5-HT6 antagonist…”
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