Search Results - "Narise, Kosuke"

Isolation, identification, and biological evaluation of HIF-1-modulating compounds from Brazilian green propolis by Hattori, Hisanori, Okuda, Kensuke, Murase, Tetsuji, Shigetsura, Yuki, Narise, Kosuke, Semenza, Gregg L., Nagasawa, Hideko

“…The tumor microenvironment is characterized by hypoxia, low-nutrient levels, and acidosis. A natural product chemistry-based approach was used to discover…”
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Optimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironment by Narise, Kosuke, Okuda, Kensuke, Enomoto, Yukihiro, Hirayama, Tasuku, Nagasawa, Hideko

“…Adaptive cellular responses resulting from multiple microenvironmental stresses, such as hypoxia and nutrient deprivation, are potential novel drug targets for…”
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Abstract 765: Drug discovery for targeting the tumor microenvironment from propolis by Nagasawa, Hideko K., Hattori, Hisanori, Narise, Kosuke, Watarai, Tatsuya, Ueda, Satoshi, Okuda, Kensuke

“…Abstract The tumor microenvironment, characterized by regions of hypoxia, low nutrition, and acidosis due to incomplete blood vessel networks, has been…”
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