Search Results - "Narges Dastmalchi"
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Tumor suppressive activity of miR-424-5p in breast cancer cells through targeting PD-L1 and modulating PTEN/PI3K/AKT/mTOR signaling pathway
Published in Life sciences (1973) (15-10-2020)“…MicroRNAs (miRs) are key modulators of cellular processes such as proliferation, apoptosis, as well as anti-cancer immune responses. Here, we evaluated the…”
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The Function of Autophagy in the Initiation, and Development of Breast Cancer
Published in Current medicinal chemistry (01-01-2024)“…Autophagy is a significant catabolic procedure that increases in stressful conditions. This mechanism is mostly triggered after damage to the organelles, the…”
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PVT1 and ZFAS1 lncRNAs expressions and their biomarker value in gastric cancer tissue sampling among Iranian population
Published in Molecular biology reports (01-11-2021)“…Background lncRNAs are modulatory factors with critical function in the tumorigenesis pathways, introducing them as promising therapeutic and diagnostic…”
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4
MicroRNA-424-5p enhances chemosensitivity of breast cancer cells to Taxol and regulates cell cycle, apoptosis, and proliferation
Published in Molecular biology reports (01-02-2021)“…Combination therapy has been considered as a potential method to overcome the BC chemoresistance. MicroRNAs (miRs) have been suggested as a therapeutic factor…”
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An Updated Review of Epigenetic-Related Mechanisms and their Contribution to Multiple Sclerosis Disease
Published in CNS & neurological disorders drug targets (01-01-2023)“…Multiple Sclerosis (MS) is a multifactorial, neurodegenerative, and inflammatory demyelination disease with incomplete remyelination in the CNS. It would be…”
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Polymorphisms and expression levels of TNP2, SYCP3, and AZFa genes in patients with azoospermia
Published in Clinical and experimental reproductive medicine (01-12-2023)“…Azoospermia (the total absence of sperm in the ejaculate) affects approximately 10% of infertile males. Despite diagnostic advances, azoospermia remains the…”
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7
The role of microRNAs in nicotine signaling
Published in EXCLI journal (01-01-2023)“…Cigarette smoking is a harmful habit that is widespread around the world. It is among the well-known lifestyle-related risk factors for many diseases…”
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DMRT1, RBMY, and AZFb genes polymorphism and expression role in azoospermia susceptibility
Published in Journal of advanced biotechnology and experimental therapeutics (01-08-2023)“…Male infertility can occur due to spermatogenesis defects. The most common causes of male infertility are azoospermia and oligospermia, which have several…”
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Inflammatory reflex disruption in COVID‐19
Published in Clinical & experimental neuroimmunology (01-11-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) was identified in Wuhan, China, in late 2019 and caused coronavirus disease 2019 (COVID‐19), which…”
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The combined therapy of miR-383-5p restoration and paclitaxel for treating MDA-MB-231 breast cancer
Published in Medical oncology (Northwood, London, England) (01-01-2022)“…The deregulation of microRNAs (miRs) has been identified in tumor development. Indeed, the restoration of tumor-suppressive miRs has been associated with…”
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The Effects of siRNA-Mediated Gene Silencing of Alpha-7 Nicotinic Acetylcholine Receptors on Drug Resistance to Oxaliplatin in Colorectal Cancer Cells
Published in Biology bulletin of the Russian Academy of Sciences (01-12-2022)“…The role of alpha-7 nicotinic acetylcholine receptor (α7nAchR) in colorectal cancer (CRC) chemoresistance, especially in Oxaliplatin (OXA)-resistant cells, has…”
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Polymorphisms and expression levels of TNP2, SYCP3, and AZFa genes in patients with azoospermia
Published in Clinical and experimental reproductive medicine (2023)“…Objective: Azoospermia (the total absence of sperm in the ejaculate) affects approximately 10% of infertile males. Despite diagnostic advances, azoospermia…”
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13
An update review of deregulated tumor suppressive microRNAs and their contribution in various molecular subtypes of breast cancer
Published in Gene (01-03-2020)“…•Various miRs have tumor-suppressive roles in BC.•The aberrant expression of TS miRs leads to enhanced cell growth, decreased apoptosis, cell migration and…”
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14
Antioxidants with two faces toward cancer
Published in Life sciences (1973) (01-10-2020)“…Antioxidants are essential in preventing the formation and suppressing the activities of reactive nitrogen and oxygen species. The aim of this study was to…”
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Alterations in the expression levels of long intergenic non-coding RNA APOC1P1-3 in cervical cancer tissue samples
Published in Nucleosides, nucleotides & nucleic acids (2023)“…lncRNAs play a crucial role in the carcinogenesis process. Thus, they have been recognized as the potential therapeutic and diagnostic biomarkers of cancers…”
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Interleukin-1 in obesity-related low-grade inflammation: From molecular mechanisms to therapeutic strategies
Published in International immunopharmacology (01-07-2021)“…•IL-1 is known a master cytokine because of its involvement in local and systemic inflammation.•Overexpression of IL-1 in adipose tissues leads to infiltrating…”
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Designing a Sequence-Based Method for Identifying 14 High-Risk Carcinogenic HPV Types in Multiple Infections
Published in Infectious disorders drug targets (01-05-2022)“…HPV tests have significant drawbacks in terms of detecting and differentiating types of the virus. PCR techniques provide timely and necessary results for…”
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Molecular mechanisms of breast cancer chemoresistance by immune checkpoints
Published in Life sciences (1973) (15-12-2020)“…Progression of resistance to chemotherapy in breast cancer (BC) has been recognized as a main factor in decreasing the survival of patients with this…”
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The Correlation Between Helicobacter pylori Infection and Lnc-OC1 Expression in Gastric Cancer Tissues in an Iranian Population
Published in Journal of gastrointestinal cancer (01-06-2021)“…Purpose The role of Lnc_OC1 in gastric cancer (GC) has not been well documented. The very purpose of the present study was to determine not only the expression…”
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BC032913 as a Novel Antisense Non-coding RNA is Downregulated in Gastric Cancer
Published in Journal of gastrointestinal cancer (01-09-2021)“…Background Long non-coding RNAs (lncRNAs) are a subset of non-coding RNAs. Abnormal expression of lncRNAs is associated with the development of cancers…”
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