Search Results - "Naresh, Nandhitha Uma"

UPRmt scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans by Shpilka, Tomer, Du, YunGuang, Yang, Qiyuan, Melber, Andrew, Uma Naresh, Nandhitha, Lavelle, Joshua, Kim, Sookyung, Liu, Pengpeng, Weidberg, Hilla, Li, Rui, Yu, Jun, Zhu, Lihua Julie, Strittmatter, Lara, Haynes, Cole M.

“…As organisms develop, individual cells generate mitochondria to fulfill physiological requirements. However, it remains unknown how mitochondrial network…”
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Mitochondrial UPR repression during Pseudomonas aeruginosa infection requires the bZIP protein ZIP-3 by Deng, Pan, Naresh, Nandhitha Uma, Du, Yunguang, Lamech, Lilian T., Yu, Jun, Zhu, Lihua Julie, Pukkila-Worley, Read, Haynes, Cole M.

“…Mitochondria generate most cellular energy and are targeted by multiple pathogens during infection. In turn, metazoans employ surveillance mechanisms such as…”
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LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria by Yang, Qiyuan, Liu, Pengpeng, Anderson, Nadine S., Shpilka, Tomer, Du, YunGuang, Naresh, Nandhitha Uma, Li, Rui, Zhu, Lihua Julie, Luk, Kevin, Lavelle, Josh, Zeinert, Rilee D., Chien, Peter, Wolfe, Scot A., Haynes, Cole M.

“…The accumulation of deleterious mitochondrial DNA (∆mtDNA) causes inherited mitochondrial diseases and ageing-associated decline in mitochondrial functions…”
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Mitochondrial genome recovery by ATFS-1 is essential for development after starvation by Uma Naresh, Nandhitha, Kim, Sookyung, Shpilka, Tomer, Yang, Qiyuan, Du, Yunguang, Haynes, Cole M.

“…Nutrient availability regulates the C. elegans life cycle as well as mitochondrial physiology. Food deprivation significantly reduces mitochondrial genome…”
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Redirection of SKN-1 abates the negative metabolic outcomes of a perceived pathogen infection by Nhan, James D., Turner, Christian D., Anderson, Sarah M., Yen, Chia-An, Dalton, Hans M., Cheesman, Hilary K., Ruter, Dana L., Naresh, Nandhitha Uma, Haynes, Cole M., Soukas, Alexander A., Pukkila-Worley, Read, Curran, Sean P.

“…Early host responses toward pathogens are essential for defense against infection. In Caenorhabditis elegans, the transcription factor, SKN-1, regulates…”
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Signaling and Regulation of the Mitochondrial Unfolded Protein Response by Naresh, Nandhitha Uma, Haynes, Cole M

“…The mitochondrial proteome encompasses more than a thousand proteins, which are encoded by the mitochondrial and nuclear genomes. Mitochondrial biogenesis and…”
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Breaks in mitochondrial DNA rig the immune response by Naresh, Nandhitha Uma, Haynes, Cole M.

“…Damage to DNA in a cellular organelle called the mitochondrion triggers an immune response in the nucleus. Mechanistic insights into this process shed light on…”
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UPR mt scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans by Shpilka, Tomer, Du, YunGuang, Yang, Qiyuan, Melber, Andrew, Uma Naresh, Nandhitha, Lavelle, Joshua, Kim, Sookyung, Liu, Pengpeng, Weidberg, Hilla, Li, Rui, Yu, Jun, Zhu, Lihua Julie, Strittmatter, Lara, Haynes, Cole M

“…As organisms develop, individual cells generate mitochondria to fulfill physiological requirements. However, it remains unknown how mitochondrial network…”
Get full text