Search Results - "Narender, T."
-
1
Mitochondrial membrane potential (MMP) regulates sperm motility
Published in In vitro cellular & developmental biology. Animal (01-10-2016)“…Sperm motility is the major decisive factor in determining male fertility. The objective of the present study was to analyse the effect of mitochondrial…”
Get full text
Journal Article -
2
Gedunin isolated from the mangrove plant Xylocarpus granatum exerts its anti-proliferative activity in ovarian cancer cells through G2/M-phase arrest and oxidative stress-mediated intrinsic apoptosis
Published in Apoptosis (London) (01-08-2020)“…Gedunin is a natural tetranorterpenoid secondary metabolite found in plants of the Meliaceae family, which has been reported for its antiparasitic, antifungal…”
Get full text
Journal Article -
3
Molecular Iodine-Mediated Domino Reaction for the Synthesis of Benzamides, 2,2-Diazidobenzofuran-3(2H)-ones and Benzoxazolones
Published in Advanced synthesis & catalysis (16-12-2013)“…A simple and efficient domino protocol has been developed for the preparation of biologically important benzamides, 2,2‐diazidobenzofuran‐3(2H)‐ones and…”
Get full text
Journal Article -
4
Pyrazoline analogues: Design, synthesis, and evaluation of anti-osteoporosis activity
Published in Bioorganic & medicinal chemistry letters (15-03-2022)“…[Display omitted] A series of pyrazoline compounds were synthesised and their osteogenic potential was explored. Out of fifteen, six compounds (3a, 4ac, 5aaa,…”
Get full text
Journal Article -
5
A simple and highly efficient method for the synthesis of chalcones by using borontrifluoride-etherate
Published in Tetrahedron letters (30-04-2007)“…Chalcones are secondary metabolites of terrestrial plants, precursors for the biosynthesis of flavonoids and exhibit various biological activities…”
Get full text
Journal Article -
6
Chebulinic acid alleviates LPS-induced inflammatory bone loss by targeting the crosstalk between reactive oxygen species/NFκB signaling in osteoblast cells
Published in Free radical biology & medicine (01-01-2023)“…Chebulinic acid (CA), a plant ellagitannin derived from Triphala, is reported to exhibit both anti-inflammatory & anti-oxidant activity apart from anti-tumour…”
Get full text
Journal Article -
7
Ecliptal, a promising natural lead isolated from Eclipta alba modulates adipocyte function and ameliorates metabolic syndrome
Published in Toxicology and applied pharmacology (01-01-2018)“…A swift increase has been observed in the number of individuals with metabolic syndrome worldwide. A number of natural compounds have been identified towards…”
Get full text
Journal Article -
8
Diastereomeric Mixture of Calophyllic and Isocalophyllic Acid Ameliorates Scopolamine-Induced Memory Impairment in Mice: Involvement of Antioxidant Defense and Cholinergic Systems
Published in Neurotoxicity research (2020)“…Dementia of Alzheimer disease type (AD) and type 2 diabetes mellitus (T2D) are two most common diseases of aging which has reached epidemic proportions…”
Get full text
Journal Article -
9
Dietary Lactobacillus acidophilus and Mannan-Oligosaccharides Alter the Lipid Metabolism and Health Indices in Broiler Chickens
Published in Probiotics and antimicrobial proteins (01-06-2021)“…The effects of dietary Lactobacillus acidophilus (LBA) and mannan-oligosaccharide (MOS) supplementation on lipid metabolism and consequent lipid profile and…”
Get full text
Journal Article -
10
Ethyl acetate fraction of Eclipta alba: a potential phytopharmaceutical targeting adipocyte differentiation
Published in Biomedicine & pharmacotherapy (01-12-2017)“…[Display omitted] Natural products have always fascinated mankind for their miraculous properties. Eclipta alba (E. alba), a medicinal herb has long been used…”
Get full text
Journal Article -
11
Preparation of novel antiproliferative emodin derivatives and studies on their cell cycle arrest, caspase dependent apoptosis and DNA binding interaction
Published in Phytomedicine (Stuttgart) (15-07-2013)“…Emodin (1) is the major bioactive compound of several herb species, which belongs to anthraquinone class of compound. As a part of our drug discovery program,…”
Get full text
Journal Article -
12
A new chemical access for 3′-acetyl-4′-hydroxychalcones using borontrifluoride–etherate via a regioselective Claisen-Schmidt condensation and its application in the synthesis of chalcone hybrids
Published in Tetrahedron letters (02-11-2011)“…A new chemical access has been developed for the synthesis of 3′-acetyl-4′-hydroxychalcones from 1-(5-acetyl-2-hydroxy-phenyl)-ethanone and various substituted…”
Get full text
Journal Article -
13
Dose-dependent effects of Asparagus adscendens root (AARR) extract on the anabolic, reproductive, and sexual behavioral activity in rats
Published in Pharmaceutical biology (01-02-2015)“…Asparagus adscendens Roxb (Liliaceae) has a promising role in modulation of various disorders such as leucorrhea, diarrhea, dysentery, diabetes, senile…”
Get more information
Journal Article -
14
Bioactivity guided isolation of analgesic and anti-inflammatory constituents of Cnestis ferruginea Vahl ex DC (Connaraceae) root
Published in Journal of ethnopharmacology (13-07-2012)“…Cnestis ferruginea (CF) Vahl ex DC (Connaraceae) is a shrub widely used in Traditional African Medicine (TAM) for the treatment of various painful and…”
Get full text
Journal Article -
15
Prenylated chalcones isolated from Crotalaria genus inhibits in vitro growth of the human malaria parasite Plasmodium falciparum
Published in Bioorganic & medicinal chemistry letters (16-05-2005)“…A chalcone 2, crotaorixin, has been isolated from the aerial parts of the Crotalaria orixensis. Its structure has been established by extensive 1D and 2D NMR…”
Get full text
Journal Article -
16
Antidyslipidemic and antioxidant activity of the constituents isolated from the leaves of Calophyllum inophyllum
Published in Phytomedicine (Stuttgart) (15-11-2012)“…In continuation of our drug discovery program on Indian medicinal plants, we isolated bioactive compounds (1–5) from the leaves of Calophyllum inophyllum and…”
Get full text
Journal Article -
17
Antihyperglycemic and antidyslipidemic agent from Aegle marmelos
Published in Bioorganic & medicinal chemistry letters (15-03-2007)“…The plant Aegle marmelos belongs to the family of Rutaceae. From the leaves of A. marmelos an alkaloidal-amide, Aegeline 2, was isolated and found to have…”
Get full text
Journal Article -
18
Lupeol derivative mitigates Echis carinatus venom-induced tissue destruction by neutralizing venom toxins and protecting collagen and angiogenic receptors on inflammatory cells
Published in Biochimica et biophysica acta (01-12-2015)“…Echis carinatus bite is a serious threat in South-Asian countries including India, as it causes highest number of deaths and terrifying long-term tissue…”
Get full text
Journal Article -
19
Evaluation of amentoflavone isolated from Cnestis ferruginea Vahl ex DC (Connaraceae) on production of inflammatory mediators in LPS stimulated rat astrocytoma cell line (C6) and THP-1 cells
Published in Journal of ethnopharmacology (27-03-2013)“…Cnestisferruginea (CF) Vahl ex DC (Connaraceae) is a shrub widely used in traditional African medicine for the treatment of various psychiatric illness and…”
Get full text
Journal Article -
20
Synthesis of novel triterpenoid (lupeol) derivatives and their in vivo antihyperglycemic and antidyslipidemic activity
Published in Bioorganic & medicinal chemistry letters (01-08-2009)“…The triterpenoid, lupeol (1) has been isolated from the leaves extract of Aegle marmelos. Few novel derivatives (2–13) were synthesized from the naturally…”
Get full text
Journal Article