Search Results - "Narayanaswami, V"

The LDL receptor binding domain of apolipoprotein E directs the relative orientation of its C-terminal segment in reconstituted nascent HDL by Kothari, S, Bala, N, Patel, A B, Donovan, A, Narayanaswami, V

“…Apolipoprotein E (apoE) (299 residues) is a highly helical protein that plays a critical role in cholesterol homeostasis. It comprises a four-helix bundle…”
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Diet-induced obesity: dopamine transporter function, impulsivity and motivation by Narayanaswami, V, Thompson, A C, Cassis, L A, Bardo, M T, Dwoskin, L P

“…Objective: A rat model of diet-induced obesity (DIO) was used to determine dopamine transporter (DAT) function, impulsivity and motivation as neurobehavioral…”
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Charged residues in the C-terminal domain of apolipoprotein A-I mediate oligomerization by Weers, P, Narayanaswami, V, Fuentes, L, Horn, J, Ellena, R, Cong, K

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Novel chimeras provide insight into structure/function activity in apolipoprotein E3 and apolipoprotein AI by Narayanaswami, V, Lek, M, Ibe, N, Beck, W, Bielicki, J, Weers, P

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Full-length apolipoprotein E protects against the neurotoxicity of an apoE-related peptide by Crutcher, K.A, Lilley, H.N, Anthony, S.R, Zhou, W, Narayanaswami, V

“…Abstract Apolipoprotein E was found to protect against the neurotoxic effects of a dimeric peptide derived from the receptor-binding region of this protein…”
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ATP-dependent S-(2,4-dinitrophenyl)glutathione transport in canalicular plasma membrane vesicles from rat liver by AKERBOOM, T. P. M, NARAYANASWAMI, V, KUNST, M, SIES, H

“…Uptake of the thioether S-(2,4-dinitrophenyl)glutathione (DNPSG) in canalicular plasma membrane vesicles from rat liver is enhanced in the presence of ATP and…”
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Bacterial expression and site-directed mutagenesis of a functional recombinant apolipoprotein by Ryan, R O, Schieve, D, Wientzek, M, Narayanaswami, V, Oikawa, K, Kay, C M, Agellon, L B

“…To facilitate structure-function studies of Manduca sexta apolipophorin III (apoLp-III), its nucleotide coding sequence was cloned from a fat body cDNA library…”
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Protein-lipid interactions of apolipophorin-III, a model exchangeable amphipathic apolipoprotein by Narayanaswami, V, Ryan, R O

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Synthesis and preclinical evaluation of [18F]FSL25.1188, a reversible PET radioligand for monoamine oxidase-B by Dahl, Kenneth, Bernard-Gauthier, Vadim, Nag, Sangram, Varnäs, Katarina, Narayanaswami, Vidya, Mahdi Moein, Mohammad, Arakawa, Ryosuke, Vasdev, Neil, Halldin, Christer

“…[Display omitted] Carbon-11 labeled SL25.1188 is a promising reversible monoamine oxidase-B (MAO-B) radioligand that was recently translated for human positron…”
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Diet-induced obesity: popamine transporter function, impulsivity and motivation by Narayanaswami, V, Thompson, A.C, Cassis, L.A, Bardo, M.T, Dwoskin, L.P

“…OBJECTIVE: A rat model of diet-induced obesity (DIO) was used to determine dopamine transporter (DAT) function, impulsivity and motivation as neurobehavioral…”
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Interhelical contacts are required for the helix bundle fold of apolipophorin III and its ability to interact with lipoproteins by Wang, Jianjun, Narayanaswami, Vasanthy, Ryan, Robert O., Sykes, Brian D.

“…Apolipophorin‐III (apoLp‐III) from the insect, Manduca sexta, is a 166‐residue exchangeable apolipoprotein that plays a critical role in the dynamics of plasma…”
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Apolipoprotein E3-mediated cellular uptake of reconstituted high-density lipoprotein bearing core 3, 10, or 17 nm hydrophobic gold nanoparticles by Chuang, Skylar T, Shon, Young-Seok, Narayanaswami, Vasanthy

“…We have developed a high-density lipoprotein (HDL)-based platform for transport and delivery of hydrophobic gold nanoparticles (AuNPs). The ability of…”
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Inter-molecular Coiled-coil Formation in Human Apolipoprotein E C-terminal Domain by Choy, Nicole, Raussens, Vincent, Narayanaswami, Vasanthy

“…Human apolipoprotein E (apoE) is composed of an N-terminal (NT) domain (residues 1–191) that bears low-density lipoprotein receptor-binding sites, and a…”
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Structural and Binding Characteristics of the Carboxyl Terminal Fragment of Apolipophorin III from Manduca sexta by Narayanaswami, Vasanthy, Kay, Cyril M, Oikawa, Kim, Ryan, Robert O

“…The molecular basis of the interaction of apolipophorin III (apoLp-III), an exchangeable apolipoprotein from hemolymph of the sphinx moth, Manduca sexta, with…”
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Fluorescence Studies of Lipid Association-Induced Conformational Adaptations of an Exchangeable Amphipathic Apolipoprotein by Narayanaswami, Vasanthy, Frolov, Andrey, Schroeder, Friedhelm, Oikawa, Kim, Kay, Cyril M., Ryan, Robert O

“…The conformational adaptability ofManduca sextaapolipophorin III (apoLp-III) has been evaluated by monitoring the spectroscopic properties of its sole tyrosine…”
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Spectroscopic and Lipid Binding Studies on the Amino and Carboxyl Terminal Fragments of Locusta migratoria Apolipophorin III by Narayanaswami, Vasanthy, Weers, Paul M. M, Bogerd, Jan, Kooiman, Frank P, Kay, Cyril M, Scraba, Douglas G, Van der Horst, Dick J, Ryan, Robert O

“…The structural basis for the lipid binding capability of Locusta migratoria apolipophorin III (apoLp-III) was assessed by characterizing the amino and carboxyl…”
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Calcium-Triggered Membrane Interaction of the α-Synuclein Acidic Tail by Tamamizu-Kato, Shiori, Kosaraju, Malathi G, Kato, Hiroyuki, Raussens, Vincent, Ruysschaert, Jean-Marie, Narayanaswami, Vasanthy

“…α-Synuclein (α-syn) is a 140-residue protein that aggregates in intraneuronal inclusions called Lewy bodies in Parkinson's disease (PD). It is composed of an…”
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Molecular basis of exchangeable apolipoprotein function by Narayanaswami, Vasanthy, Ryan, Robert O

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Development of a novel reversible F-18 labelled SL25.1188 analog for the detection of MAO-B activity by Nag, S, Dahl, K, Bernard-Gauthier, V, Varnas, K, Narayanaswami, V, Moein, M, Arakawa, R, Vasdev, N, Halldin, C

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Synthesis of a novel 18 F-labeled radioligand for monoamine oxidase-B and preliminary PET imaging in non-human primate by Dahl, K, Bernard-Gauthier, V, Nag, S, Varnaosi, K, Narayanaswami, V, Moein, M, Arakawa, R, Vasdev, N, Halldin, C

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