Search Results - "Narasimhan, Kishore Kumar S"

Intravenous recombinant cerebellin 1 treatment restores signalling by spinal glutamate delta 1 receptors and mitigates chronic pain by Sabnis, Siddhesh S, S Narasimhan, Kishore Kumar, Chettiar, Poojashree B, Gakare, Sukanya G, Shelkar, Gajanan P, Asati, Devansh G, Thakur, Shriti S, Dravid, Shashank M

“…Chronic pain remains a major clinical problem that needs effective therapeutic agents. Glutamate delta 1 (GluD1) receptors and the protein cerebellin 1 (Cbln1)…”
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Triad role of hepcidin, ferroportin, and Nrf2 in cardiac iron metabolism: From health to disease by Jayakumar, Deepthy, S. Narasimhan, Kishore Kumar, Periandavan, Kalaiselvi

“…Iron is an essential trace element required for several vital physiological and developmental processes, including erythropoiesis, bone, and neuronal…”
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GluN2D Subunit in Parvalbumin Interneurons Regulates Prefrontal Cortex Feedforward Inhibitory Circuit and Molecular Networks Relevant to Schizophrenia by Gawande, Dinesh Y., S. Narasimhan, Kishore Kumar, Shelkar, Gajanan P., Pavuluri, Ratnamala, Stessman, Holly A.F., Dravid, Shashank M.

“…Parvalbumin interneuron (PVI) activity synchronizes the medial prefrontal cortex circuit for normal cognitive function, and its impairment may contribute to…”
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Glutamate delta-1 receptor regulates oligodendrocyte progenitor cell differentiation and myelination in normal and demyelinating conditions by Gakare, Sukanya G, Bhatt, Jay M, Narasimhan, Kishore Kumar S, Dravid, Shashank M

“…In this study, we investigated the role of glutamate delta 1 receptor (GluD1) in oligodendrocyte progenitor cell (OPC)-mediated myelination during basal…”
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GluN2D subunit-containing NMDA receptors regulate reticular thalamic neuron function and seizure susceptibility by Gawande, Dinesh Y., Shelkar, Gajanan P., Narasimhan, Kishore Kumar S., Liu, Jinxu, Dravid, Shashank M.

“…Thalamic regulation of cortical function is important for several behavioral aspects including attention and sensorimotor control. This region has also been…”
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Glutamate delta 1 receptor regulates autophagy mechanisms and affects excitatory synapse maturation in the somatosensory cortex by Gawande, Dinesh Y., S. Narasimhan, Kishore Kumar, Bhatt, Jay M., Pavuluri, Ratnamala, Kesherwani, Varun, Suryavanshi, Pratyush S., Shelkar, Gajanan P., Dravid, Shashank M.

“…The glutamate delta family of receptors is composed of GluD1 and GluD2 and serve as synaptic organizers. We have previously demonstrated several autism-like…”
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Reductive stress promotes protein aggregation and impairs neurogenesis by S Narasimhan, Kishore Kumar, Devarajan, Asokan, Karan, Goutam, Sundaram, Sandhya, Wang, Qin, van Groen, Thomas, Monte, Federica del, Rajasekaran, Namakkal S.

“…Redox homeostasis regulates key cellular signaling in both physiology and pathology. While perturbations result in shifting the redox homeostasis towards…”
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Morinda citrifolia mitigates rotenone-induced striatal neuronal loss in male Sprague-Dawley rats by preventing mitochondrial pathway of intrinsic apoptosis by Kishore Kumar, S. Narasimhan, Deepthy, Jayakumar, Saraswathi, Uthamaraman, Thangarajeswari, Mohan, Yogesh Kanna, Sathyamoorthy, Ezhil, Pannerselvam, Kalaiselvi, Periandavan

“…Objectives: Parkinson disease (PD) is a neurodegenerative disorder affecting mainly the motor system, as a result of death of dopaminergic neurons in the…”
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Amelioration of apoptotic events in the skeletal muscle of intra-nigrally rotenone-infused Parkinsonian rats by Morinda citrifolia--up-regulation of Bcl-2 and blockage of cytochrome c release by Narasimhan, Kishore Kumar S, Paul, Liya, Sathyamoorthy, Yogesh Kanna, Srinivasan, Ashokkumar, Chakrapani, Lakshmi Narasimhan, Singh, Abhilasha, Ravi, Divya Bhavani, Krishnan, Thulasi Raman, Velusamy, Prema, Kaliappan, Kathiravan, Radhakrishnan, Rameshkumar, Periandavan, Kalaiselvi

“…Parkinson's disease is a progressive neurodegenerative movement disorder with the cardinal symptoms of bradykinesia, resting tremor, rigidity, and postural…”
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Role of Nrf2 dysfunction in the pathogenesis of diabetic nephropathy: Therapeutic prospect of epigallocatechin-3-gallate by Mohan, Thangarajeswari, Narasimhan, Kishore Kumar S., Ravi, Divya Bhavani, Velusamy, Prema, Chandrasekar, Navvi, Chakrapani, Lakshmi Narasimhan, Srinivasan, Ashokkumar, Karthikeyan, Porkodi, Kannan, Pugazhendhi, Tamilarasan, Bhavani, Johnson, Thanka, Kalaiselvan, Parkavi, Periandavan, Kalaiselvi

“…Diabetic nephropathy (DN), a progressive kidney disease afflicts more than 20 and up to 40% of the diabetic population and it is characterized by persistent…”
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Morinda citrifolia and Its Active Principle Scopoletin Mitigate Protein Aggregation and Neuronal Apoptosis through Augmenting the DJ-1/Nrf2/ARE Signaling Pathway by Periandavan, Kalaiselvi, Rajasekaran, Namakkal Soorappan, Uthamaraman, Saraswathi, Ravi, Divya Bhavani, Mohan, Thangarajeswari, Srinivasan, Ashokkumar, Velusamy, Prema, Jayakumar, Deepthy, Narasimhan, Kishore Kumar S., Sathyamoorthy, Yogesh Kanna

“…Given the role of oxidative stress in PD pathogenesis and off-target side effects of currently available drugs, several natural phytochemicals seem to be…”
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Emerging Role of Nrf2 in Altering Cardiac Iron Metabolism during Myocardial Infarction by Jayakumar, Deepthy, S Narasimhan, Kishore Kumar, Rajkumar, Abinayaa, Raghunathan, Malathi, Sundaram, Sandhya, Periandavan, Kalaiselvi

“…Cardiac function demands a combination of iron availability for its high energy requirement and tight regulation of redox signaling. Nuclear factor…”
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GluN2D subunit in parvalbumin interneurons regulates prefrontal cortex feed-forward inhibitory circuit and molecular networks relevant to schizophrenia by Gawande, Dinesh Y., Narasimhan, Kishore Kumar S., Shelkar, Gajanan P., Pavuluri, Ratnamala, Stessman, Holly A. F., Dravid, Shashank M.

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Reductive Stress Promotes Protein Aggregation in Neuro-2a cells by Kumar S Narasimhan, Kishore, Devarajan, Asokan, Karan, Goutam, Wang, Qin, Monte, Federica del, Namakkal-Soorappan, Rajasekaran

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miRNA Signatures for a Human Proteotoxic Cardiac Disease by Nassour, Lauren, Sunny, Sini, Jyothidasan, Arun, Kumar S Narasimhan, Kishore, Dalley, Brian, Benjamin, Ivor, Namakkal-Soorappan, Rajasekaran

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Reductive Stress Impairs Neurogenesis via GSK3β Signaling in Vitro by Kumar S Narasimhan, Kishore, Sundaram, Sandhya, Ramamurthy, Muralidharan T., van Groen, Thomas, Wang, Qin, Monte, Federica del, Namakkal-Soorappan, Rajasekaran

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