Search Results - "Narang, S A"

Diagnostic Value of Lactate Levels in Acute Abdomen Disorders by Verma, Indu, Kaur, Satinder, Goyal, Subash, Goyal, Shweta, Multani, J. S., Narang, A. P. S.

“…The supply of oxygen is limited in certain intra abdominal conditions due to direct vascular invasion or inflammatory process, resulting in high lactate…”
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Structure of a Single-Chain Antibody Variable Domain (Fv) Fragment Complexed with a Carbohydrate Antigen at 1.7-Å Resolution by Zdanov, Alexander, Li, Yunge, Bundle, David R., Deng, Su-Jun, MacKenzie, C. Roger, Narang, Saran A., Young, N. Martin, Cygler, Miroslaw

“…We describe here the 1.7-Å resolution structure of a single-chain antibody variable domain (scFv) molecule, based on the carbohydrate-binding antibody Se155-4,…”
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Selection of antibody single-chain variable fragments with improved carbohydrate binding by phage display by SU-JUN DENG, MACKENZIE, C. R, SADOWSKA, J, MICHNIEWICZ, J, YOUNG, N. M, BUNDLE, D. R, NARANG, S. A

“…A single-chain variable fragment (Fv) version of a murine monoclonal antibody, Se155-4, specific for Salmonella serogroup B O-polysaccharide, was used as a…”
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Serial composition of human milk in preterm and term mothers by Narang, A P S, Bains, H S, Kansal, Shivani, Singh, D

“…Human milk samples were collected from 86 mothers induced in the study on days 3, 7, 14 and 28 of lactation. The mothers were divided into three groups on the…”
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Bacterial expression and secretion of various single-chain Fv genes encoding proteins specific for a Salmonella serotype B O-antigen by ANAND, N. N, MANDAL, S, MACKENZIE, C. R, SADOWSKA, J, SIGURSKOLD, B, YOUNG, N. M, BUNDLE, D. R, NARANG, S. A

“…Active single-chain Fv molecules encoded by synthetic genes have been expressed and secreted to the periplasm of Escherichia coli using the ompA secretory…”
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Basis for Selection of Improved Carbohydrate-Binding Single-Chain Antibodies from Synthetic Gene Libraries by Deng, Su-Jun, MacKenzie, C. Roger, Hirama, Tomoko, Brousseau, Roland, Lowary, Todd L., Young, N. Martin, Bundle, David R., Narang, Saran A.

“…A technique is described for the simultaneous and controlled random mutation of all three heavy or light chain complementarity-determining regions (CDRs) in a…”
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Effect of immobilisation stress on lipid peroxidation and lipid profile in rabbits by Lata, Hem, Ahuja, G K, Narang, A P S, Walia, Lily

“…Stress is one of the basic factors in the aetiology of a number of diseases such as atherosclerosis, coronary heart disease, aging, liver disease etc. Hence…”
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Rapid imaging of human melanoma xenografts using an scFv fragment of the human monoclonal antibody H11 labelled with 111In by REILLY, R M, MAITI, P K, KIARASH, R, PRASHAR, A K, FAST, D G, ENTWISTLE, J, DAN, M D, NARANG, S A, FOOTE, S, KAPLAN, H A

“…H11 is a human IgM monoclonal antibody which recognizes a novel tumour-associated antigen expressed on melanoma, glioma, breast cancer, colon cancer, prostate…”
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Identification of two distinct Bacillus circulans xylanases by molecular cloning of the genes and expression in Escherichia coli by Yang, R.C.A, MacKenzie, C.R, Bilous, D, Narang, S.A

“…Two genes coding for xylanase synthesis in Bacillus circulans were cloned and expressed in Escherichia coli. After digestion of genomic DNA from Bacillus…”
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Cationic Lipids with Increased DNA Binding Affinity for Nonviral Gene Transfer in Dividing and Nondividing Cells by Narang, Ajit S, Thoma, Laura, Miller, Duane D, Mahato, Ram I

“…Effect of headgroup structure on catonic lipid-mediated transfection was investigated with either a (i) tertiary amine, (ii) quaternary amine with a hydroxyl,…”
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Use of arylsulfonyltriazoles for the synthesis of oligonucleotides by the triester approach by Katagiri, N, Itakura, K, Narang, S. A

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Hyperexpression of a Bacillus circulans xylanase gene in Escherichia coli and characterization of the gene product by Yang, R.C.A, MacKenzie, C.R, Bilous, D, Narang, S.A

“…A 4.0-kilobase (kb) fragment of Bacillus circulans genomic DNA inserted into pUC19 and encoding endoxylanase activity was subjected to a series of subclonings…”
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Synthesis and expression in Escherichia coli of cistronic DNA encoding an antibody fragment specific for a Salmonella serotype B O-antigen by Anand, N N, Dubuc, G, Phipps, J, MacKenzie, C R, Sadowska, J, Young, N M, Bundle, D R, Narang, S A

“…A 1460-bp DNA encoding the two chains of the antigen-binding fragment (Fab) portion of a monoclonal antibody have been chemically synthesized and expressed in…”
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Short Synthetic Oligodeoxyribonucleotide Leader Sequences Enhance Accumulation of Human Proinsulin Synthesized in Escherichia coli by Sung, Wing L., Yao, Fei-Long, Zahab, Diana M., Narang, Saran A.

“…Enhanced accumulation of human proinsulin synthesized in Escherichia coli has been achieved by inserting a short leader of homooligopeptide at the amino end of…”
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Optimal Design Features of Camelized Human Single-domain Antibody Libraries by Tanha, J, Xu, P, Chen, Z, Ni, F, Kaplan, H, Narang, S A, MacKenzie, C R

“…We have constructed a human V H library based on a camelized V H sequence. The library was constructed with complete randomization of 19 of the 23 CDR3…”
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Simultaneous randomization of antibody CDRs by a synthetic ligase chain reaction strategy by SU-JUN DENG, MACKENZIE, C. R, NARANG, S. A

“…Images…”
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Plasma homocysteine and insulin in diabetic nephropathy: relationship to body mass index by Sandhu, J S, Singh, Inderpal, Aggarwal, S P, Narang, A P S, Sandhu, P

“…The data on plasma homocysteine and endogenous insulin in type 2 diabetes mellitus with nephropathy and relationship to body mass index (BMI) is particularly…”
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Nucleotide sequence of a Bacillus circulans xylanase gene by YANG, R. C. A, MACKENZIE, C. R, NARANG, S. A

“…A 4.3 kb Eco RI fragment of Bacillus circulans DNA was inserted into pUC19 and cloned in Escherichia coli . The insert of the resulting chimeric plasmid,…”
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Analysis by Surface Plasmon Resonance of the Influence of Valence on the Ligand Binding Affinity and Kinetics of an Anti-carbohydrate Antibody (∗) by MacKenzie, C. Roger, Hirama, Tomoko, Deng, Su-jun, Bundle, David R., Narang, Saran A., Young, N. Martin

“…The kinetics of ligand binding by Se155-4, an antibody specific for the Salmonella serogroup B O-polysaccharide, were studied by surface plasmon resonance…”
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Sequential Interchange of Four Amino Acids from Blood Group B to Blood Group A Glycosyltransferase Boosts Catalytic Activity and Progressively Modifies Substrate Recognition in Human Recombinant Enzymes by Seto, Nina O.L., Palcic, Monica M., Compston, Catherine A., Li, Hong, Bundle, David R., Narang, Saran A.

“…The human blood group A and B glycosyltransferase enzymes are highly homologous and the alteration of four critical amino acid residues (Arg-176 → Gly, Gly-235…”
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