Search Results - "Narala, Rachan"

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    S1356 Benefits of Corticosteroids in Alcohol-Associated Hepatitis Complicated by Acute-on-Chronic Liver Failure by Xu, Mimi, Tien, Christine, Lehoang, David, Kong, Niwen, Narala, Rachan, Pimienta, Michael, Ayyala-Somayajula, Divya, Terrault, Norah

    Published in The American journal of gastroenterology (01-10-2023)
    “…Overall, 23 (21.1%) patients died within 30 days of hospital admission and 33 (30.3%) died within 90 days of admission (Figure 1). Treatment with steroids…”
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    A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling by Grimsey, Neil J., Narala, Rachan, Rada, Cara C., Mehta, Sohum, Stephens, Bryan S., Kufareva, Irina, Lapek, John, Gonzalez, David J., Handel, Tracy M., Zhang, Jin, Trejo, JoAnn

    Published in Cell reports (Cambridge) (18-09-2018)
    “…Ubiquitination is essential for protein degradation and signaling and pivotal to many physiological processes. Ubiquitination of a subset of G-protein-coupled…”
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    Underwater versus conventional endoscopic mucosal resection for colorectal lesions: An updated meta-analysis of randomized controlled trials by Chowdhury, Aneesa Rahman, Kim, Jin Sun, Xu, Mimi, Tom, Chloe, Narala, Rachan, Kong, Niwen, Lee, Helen, Vazquez, Alejandro, Sahakian, Ara, Phan, Jennifer, Buxbaum, James

    Published in Endoscopy International Open (01-10-2023)
    “…Abstract Background and study aims Colorectal malignancy is a leading cause of death. Conventional endoscopic mucosal resection (CEMR) is a strategy used to…”
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    G protein–coupled receptors activate p38 MAPK via a non-canonical TAB1–TAB2– and TAB1–TAB3–dependent pathway in endothelial cells by Grimsey, Neil J., Lin, Ying, Narala, Rachan, Rada, Cara C., Mejia-Pena, Hilda, Trejo, JoAnn

    Published in The Journal of biological chemistry (12-04-2019)
    “…Endothelial dysfunction is induced by inflammatory mediators including multiple G protein–coupled receptor (GPCR) agonists. However, the GPCR signaling…”
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    Endothelial GPCRs Activate p38 MAPK Inflammatory Signaling Via Non‐canonical TAB1, 2 and 3‐dependent Pathways by Lin, Ying, Narala, Rachan, Grimsey, Neil, Trejo, JoAnn

    Published in The FASEB journal (01-04-2018)
    “…Vasculature disease is a leading cause of morbidity and mortality worldwide. A hallmark of vascular inflammation is endothelial cell dysfunction, which is…”
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    Endosomal GPCR signaling: Tyrosine Phosphorylation of a Peptide Linker in NEDD4‐2 Increases Ligase Activity to Promote p38 Proinflammatory Signaling by Grimsey, Neil J., Rada, Cara C., Narala, Rachan, Stephens, Bryan S., Mehta, Sohum J., Lapek, John J., Handel, Tracy M., Zhang, Jin J., Gonzalez, David J., Trejo, JoAnn

    Published in The FASEB journal (01-04-2018)
    “…The regulation of G protein‐coupled receptor (GPCR) signaling is essential for vascular homeostasis and inflammatory responses during disease and injury. MAPK…”
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    Ubiquitin plays an atypical role in GPCR‐induced p38 MAP kinase activation on endosomes by Grimsey, Neil, Narala, Rachan, Aguilar, Berenice, Rada, Cara, Smith, Thomas, Soohoo, Amanda, Puthenveedu, manojkumar, Nizet, Victor, Trejo, JoAnn J

    Published in The FASEB journal (01-04-2016)
    “…Abstract only Protease‐activated receptor 1 (PAR1) is a G protein–coupled receptor (GPCR) for thrombin and promotes inflammatory responses through multiple…”
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