Search Results - "Nara, Takayuki Y"

Structure, function, and dietary regulation of Δ6, Δ5, and Δ9 desaturases by NAKAMURA, Manabu T, NARA, Takayuki Y

“…▪ Abstract  Fatty acid desaturases introduce a double bond in a specific position of long-chain fatty acids, and are conserved across kingdoms. Degree of…”
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Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration by Stroud, Chad K., Nara, Takayuki Y., Roqueta-Rivera, Manuel, Radlowski, Emily C., Lawrence, Peter, Zhang, Ying, Cho, Byung H., Segre, Mariangela, Hess, Rex A., Brenna, J. Thomas, Haschek, Wanda M., Nakamura, Manabu T.

“…Delta-6 desaturase (D6D) catalyzes the first step in the synthesis of highly unsaturated fatty acids (HUFA) such as arachidonic (AA), docosapentaenoic…”
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Milk Basic Protein Facilitates Increased Bone Mass in Growing Mice by ONO-OHMACHI, Aiko, ISHIDA, Yuko, MORITA, Yoshikazu, KATO, Ken, NARA, Takayuki Y.

“…Milk basic protein (MBP) comprises a group of basic whey proteins and is effective in preventing bone loss by promoting bone deposition (bone formation) and…”
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Milk basic protein increases ghrelin secretion and bone mineral density in rodents by Ishida, Yuko, Chacrabati, Rakhi, Ono-Ohmachi, Aiko, Gong, Zhi, Ikenoya, Chika, Aizawa, Sayaka, Nara, Takayuki Y, Morita, Yoshikazu, Kato, Ken, Sakai, Takafumi, Sakata, Ichiro

“…Abstract Objectives Milk basic protein (MBP), a mixture of proteins isolated from bovine milk, is known to increase bone formation. Ghrelin, a stomach-derived…”
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Mechanisms of regulation of gene expression by fatty acids by Nakamura, M.T, Cheon, Y, Li, Y, Nara, T.Y

“…Fatty acids (FA) regulate the expression of genes involved in lipid and energy metabolism. In particular, two transcription factors, sterol regulatory element…”
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Functional immobilization of racemase by adsorption on folded-sheet mesoporous silica by Nara, Takayuki Y., Togashi, Hideaki, Sekikawa, Chisato, Inoh, Keita, Hisamatsu, Kanako, Sakaguchi, Kengo, Mizukami, Fujio, Tsunoda, Tatsuo

“…Alanine racemase from Geobacillus stearothermophilus was physically immobilized on folded-sheet mesoporous silica (FSM) with pore diameters of 4 or 8.5 nm, and…”
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Use of zeolite to refold a disulfide-bonded protein by Nara, Takayuki Y., Togashi, Hideaki, Sekikawa, Chisato, Kawakami, Masayuki, Yaginuma, Nakatsugu, Sakaguchi, Kengo, Mizukami, Fujio, Tsunoda, Tatsuo

“…Zeolites are microporous crystalline aluminosilicates with a highly ordered structure. Using zeolite beta as an adsorbent, denatured/reduced hen egg lysozyme…”
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High-throughput protein refolding screening method using zeolite by Nara, Takayuki Y., Togashi, Hideaki, Sekikawa, Chisato, Sakaguchi, Kengo, Mizukami, Fujio, Tsunoda, Tatsuo

“…We established a 96‐well‐plate‐based refolding screening system using zeolite. In this system, protein denatured and solubilized with 6 M guanidine…”
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Cheese consumption prevents fat accumulation in the liver and improves serum lipid parameters in rats fed a high-fat diet by Higurashi, Satoshi, Ogawa, Akihiro, Nara, Takayuki Y., Kato, Ken, Kadooka, Yukio

“…Cheese consumption has been reported to reduce the risk of metabolic syndrome; however, the mechanisms by which cheese prevents these disorders are not fully…”
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Dietary fructose induces a wide range of genes with distinct shift in carbohydrate and lipid metabolism in fed and fasted rat liver by Koo, Hyun-Young, Wallig, Matthew A., Chung, Byung Hong, Nara, Takayuki Y., Cho, B.H. Simon, Nakamura, Manabu T.

“…Dietary fructose has been suspected to contribute to development of metabolic syndrome. However, underlying mechanisms of fructose effects are not well…”
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Modulation of brown adipocyte activity by milk by-products: Stimulation of brown adipogenesis by buttermilk by Asano, Hiroki, Kida, Ryosuke, Muto, Kengo, Nara, Takayuki Y., Kato, Ken, Hashimoto, Osamu, Kawada, Teruo, Matsui, Tohru, Funaba, Masayuki

“…Brown adipocytes dissipate chemical energy in the form of heat through the expression of mitochondrial uncoupling protein 1 (Ucp1); Ucp1 expression is further…”
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Improvement of aldehyde tolerance and sequential aldol condensation activity of deoxyriboaldolase via immobilization on interparticle pore type mesoporous silica by Nara, Takayuki Y., Togashi, Hideaki, Ono, Seigo, Egami, Miki, Sekikawa, Chisato, Suzuki, Yo-hei, Masuda, Isao, Ogawa, Jun, Horinouchi, Nobuyuki, Shimizu, Sakayu, Mizukami, Fujio, Tsunoda, Tatsuo

“…[Display omitted] ▶ KpDERA was successfully immobilized on interparticle pore type mesoporous silica. ▶ IMS immobilized KpDERA exhibited superior aldehyde…”
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Dietary lycopene downregulates carotenoid 15,15'-monooxygenase and PPAR-gamma in selected rat tissues by Zaripheh, Susan, Nara, Takayuki Y, Nakamura, Manabu T, Erdman, Jr, John W

“…In vitro studies have suggested that lycopene is an efficient substrate for carotenoid 9'10'-monooxygenase II (CMO2) but an inhibitor of carotenoid…”
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Peroxisome proliferator-activated receptor alpha is required for feedback regulation of highly unsaturated fatty acid synthesis by Li, Yue, Nara, Takayuki Y, Nakamura, Manabu T

“…Delta6 desaturase (D6D), the rate-limiting enzyme for highly unsaturated fatty acid (HUFA) synthesis, is induced by essential fatty acid-deficient diets…”
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The E-box like sterol regulatory element mediates the suppression of human Δ-6 desaturase gene by highly unsaturated fatty acids by Nara, Takayuki Y, He, Wei Song, Tang, Chongren, Clarke, Steven D, Nakamura, Manabu T

“…Δ-6 Desaturase (D6D) catalyzes the first step of the synthesis of highly unsaturated fatty acids (HUFA) that play pivotal roles in many biological functions…”
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Interaction between Lim15/Dmc1 and the homologue of the large subunit of CAF-1 - a molecular link between recombination and chromatin assembly during meiosis by Ishii, Satomi, Koshiyama, Akiyo, Hamada, Fumika N, Nara, Takayuki Y, Iwabata, Kazuki, Sakaguchi, Kengo, Namekawa, Satoshi H

“…In eukaryotes, meiosis leads to genetically variable gametes through recombination between homologous chromosomes of maternal and paternal origin. Chromatin…”
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Delayed induction of Δ-6 and Δ-5 desaturases by a peroxisome proliferator by Song He, Wei, Nara, Takayuki Y, Nakamura, Manabu T

“…Δ-6 Desaturase (D6D) is the key enzyme for the synthesis of highly unsaturated fatty acids (HUFA) such as arachidonic acid (AA) and docosahexaenoic acid (DHA)…”
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Proliferating cell nuclear antigen (PCNA) interacts with a meiosis-specific RecA homologues, Lim15/Dmc1, but does not stimulate its strand transfer activity by Hamada, Fumika N., Koshiyama, Akiyo, Namekawa, Satoshi H., Ishii, Satomi, Iwabata, Kazuki, Sugawara, Hiroko, Nara, Takayuki Y., Sakaguchi, Kengo, Sawado, Tomoyuki

“…PCNA is a multi-functional protein that is involved in various nuclear events. Here we show that PCNA participates in events occurring during early meiotic…”
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α-Amylase immobilization capacities of mesoporous silicas with different morphologies and surface properties by Hisamatsu, Kanako, Shiomi, Toru, Matsuura, Shun-ichi, Nara, Takayuki Y., Tsunoda, Tatsuo, Mizukami, Fujio, Sakaguchi, Kengo

“…α-Amylase was encapsulated in several mesoporous materials (folded sheet mesoporous silica (FSM), cubic mesoporous silica (KIT-6), and two-dimensional…”
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[alpha]-Amylase immobilization capacities of mesoporous silicas with different morphologies and surface properties by Hisamatsu, Kanako, Shiomi, Toru, Matsuura, Shun-ichi, Nara, Takayuki Y, Tsunoda, Tatsuo, Mizukami, Fujio, Sakaguchi, Kengo

“…α-Amylase was encapsulated in several mesoporous materials (folded sheet mesoporous silica (FSM), cubic mesoporous silica (KIT-6), and two-dimensional…”
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