Search Results - "Napoli, Eleonora"

Molecular, Translational and Clinical Research on the Two Most Common Forms of Neurodegenerative Dementia: Alzheimer's Disease and Dementia with Lewy Bodies by Napoli, Eleonora

“…While not a specific disease, dementia is a term used to describe the deterioration of cognitive function beyond what would be expected because of natural…”
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Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults by Dhir, Shibani, Tarasenko, Maya, Napoli, Eleonora, Giulivi, Cecilia

“…Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of enzymes, mostly with mitochondrial localization. Some…”
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Sulforaphane improves mitochondrial metabolism in fibroblasts from patients with fragile X-associated tremor and ataxia syndrome by Napoli, Eleonora, Flores, Amanda, Mansuri, Yasmeen, Hagerman, Randi J., Giulivi, Cecilia

“…CGG expansions between 55 and 200 in the 5′-untranslated region of the fragile-X mental retardation gene (FMR1) increase the risk of developing the late-onset…”
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Executive Functions and Symptom Severity in an Italian Sample of Intellectually Able Preschoolers with Autism Spectrum Disorder by Valeri, Giovanni, Casula, Laura, Napoli, Eleonora, Stievano, Paolo, Trimarco, Barbara, Vicari, Stefano, Scalisi, Teresa Gloria

“…A novel battery (BAFE; Valeri et al. 2015) was used in order to assess three executive function (EF) abilities (working memory, inhibition and shifting) in a…”
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Cell Therapy in Parkinson's Disease: Host Brain Repair Machinery Gets a Boost From Stem Cell Grafts by Napoli, Eleonora, Borlongan, Cesar V.

“…This commentary highlights the major findings and future research directions arising from the recent publication by Zuo and colleagues in Stem Cells 2017 (in…”
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Assessment of Psychopathological Comorbidities in Children and Adolescents With Autism Spectrum Disorder Using the Child Behavior Checklist by Guerrera, Silvia, Menghini, Deny, Napoli, Eleonora, Di Vara, Silvia, Valeri, Giovanni, Vicari, Stefano

“…Autism spectrum disorder (ASD) is characterized by psychiatric and behavioral comorbidities. The Child Behavior Checklist (CBCL) provides valid and…”
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Toxicity of the flame-retardant BDE-49 on brain mitochondria and neuronal progenitor striatal cells enhanced by a PTEN-deficient background by Napoli, Eleonora, Hung, Connie, Wong, Sarah, Giulivi, Cecilia

“…Polybrominated diphenyl ethers (PBDEs) represent an important group of flame retardants extensively used, tonnage of which in the environment has been steadily…”
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Endogenous repair mechanisms enhanced in Parkinson's disease following stem cell therapy by Napoli, Eleonora

“…This mini-review highlights the innovative observation that transplanted human neural stem cells can bring about endogenous brain repair through the…”
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Cooperative parent-mediated therapy for Italian preschool children with autism spectrum disorder: a randomized controlled trial by Valeri, Giovanni, Casula, Laura, Menghini, Deny, Amendola, Filomena Alessandra, Napoli, Eleonora, Pasqualetti, Patrizio, Vicari, Stefano

“…Parent-mediated intervention is widely used for pre-schoolers with autism spectrum disorder (ASD). Previous studies indicate small-to-moderate effects on…”
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Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine by Song, Gyu, Napoli, Eleonora, Wong, Sarah, Hagerman, Randi, Liu, Siming, Tassone, Flora, Giulivi, Cecilia

“…A 55-200 expansion of the CGG nucleotide repeat in the 5'-UTR of the fragile X mental retardation 1 gene ( ) is the hallmark of the triplet nucleotide disease…”
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Frataxin deficiency leads to defects in expression of antioxidants and Nrf2 expression in dorsal root ganglia of the Friedreich's ataxia YG8R mouse model by Shan, Yuxi, Schoenfeld, Robert A, Hayashi, Genki, Napoli, Eleonora, Akiyama, Tasuku, Iodi Carstens, Mirela, Carstens, Earl E, Pook, Mark A, Cortopassi, Gino A

“…Oxidative stress is thought to be involved in Friedreich's ataxia (FRDA), yet it has not been demonstrated in the target neurons that are first to degenerate…”
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Characterization of Clinical Manifestations in the Co-occurring Phenotype of Attention Deficit/Hyperactivity Disorder and Autism Spectrum Disorder by Carta, Alessandra, Fucà, Elisa, Guerrera, Silvia, Napoli, Eleonora, Valeri, Giovanni, Vicari, Stefano

“…Comorbidity between attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) is a frequently reported condition. However, the…”
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Altered Bioenergetics in Primary Dermal Fibroblasts from Adult Carriers of the FMR1 Premutation Before the Onset of the Neurodegenerative Disease Fragile X-Associated Tremor/Ataxia Syndrome by Napoli, Eleonora, Song, Gyu, Wong, Sarah, Hagerman, Randi, Giulivi, Cecilia

“…Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late onset neurodegenerative disorder, characterized by tremors, ataxia, impaired coordination, and…”
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Defective mitochondrial disulfide relay system, altered mitochondrial morphology and function in Huntington's disease by Napoli, Eleonora, Wong, Sarah, Hung, Connie, Ross-Inta, Catherine, Bomdica, Prithvi, Giulivi, Cecilia

“…A number of studies have been conducted that link mitochondrial dysfunction (MD) to Huntington's disease (HD); however, contradicting results had resulted in a…”
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Beyond autophagy: a novel role for autism-linked Wdfy3 in brain mitophagy by Napoli, Eleonora, Song, Gyu, Panoutsopoulos, Alexios, Riyadh, M. Asrafuzzaman, Kaushik, Gaurav, Halmai, Julian, Levenson, Richard, Zarbalis, Konstantinos S., Giulivi, Cecilia

“…WD repeat and FYVE domain-containing 3 ( WDFY3 ; also known as Autophagy-Linked FYVE or Alfy) is an identified intellectual disability, developmental delay and…”
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Evidence of reactive oxygen species-mediated damage to mitochondrial DNA in children with typical autism by Napoli, Eleonora, Wong, Sarah, Giulivi, Cecilia

“…The mitochondrial genome (mtDNA) is particularly susceptible to damage mediated by reactive oxygen species (ROS). Although elevated ROS production and elevated…”
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Brain Atrophy and White Matter Damage Linked to Peripheral Bioenergetic Deficits in the Neurodegenerative Disease FXTAS by Wang, Junyi, Napoli, Eleonora, Kim, Kyoungmi, McLennan, Yingratana A, Hagerman, Randi J, Giulivi, Cecilia

“…Fragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder affecting subjects (premutation carriers) with a 55-200 CGG-trinucleotide…”
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Stem Cell Therapy: Repurposing Cell-Based Regenerative Medicine Beyond Cell Replacement by Napoli, Eleonora, Lippert, Trenton, Borlongan, Cesar V

“…Stem cells exhibit simple and naive cellular features, yet their exact purpose for regenerative medicine continues to elude even the most elegantly designed…”
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Lipid-based DNA/siRNA transfection agents disrupt neuronal bioenergetics and mitophagy by Napoli, Eleonora, Liu, Siming, Marsilio, Ilaria, Zarbalis, Konstantinos, Giulivi, Cecilia

“…A multitude of natural and artificial compounds have been recognized to modulate autophagy, providing direct or, through associated pathways, indirect entry…”
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Deficits in Prenatal Serine Biosynthesis Underlie the Mitochondrial Dysfunction Associated with the Autism-Linked FMR1 Gene by Nolin, Sarah L., Napoli, Eleonora, Flores, Amanda, Hagerman, Randi J., Giulivi, Cecilia

“…Fifty-five to two hundred CGG repeats (called a premutation, or PM) in the 5′-UTR of the FMR1 gene are generally unstable, often expanding to a full mutation…”
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