Search Results - "Napoli, Andrew A"
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No evident association between efavirenz use and suicidality was identified from a disproportionality analysis using the FAERS database
Published in Journal of the International AIDS Society (01-01-2014)“…Objective To assess the potential association of selected antiretrovirals (ARVs), including efavirenz, with suicidality. Design Retrospective analysis of the…”
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Signatures of Protein-DNA Recognition in Free DNA Binding Sites
Published in Journal of molecular biology (06-03-2009)“…One obstacle to achieving complete understanding of the principles underlying sequence-dependent recognition of DNA is the paucity of structural data for DNA…”
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Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP–DNA Complex: Recognition of Pyrimidine-Purine and Purine-Purine Steps
Published in Journal of molecular biology (17-03-2006)“…The catabolite activator protein (CAP) bends DNA in the CAP–DNA complex, typically introducing a sharp DNA kink, with a roll angle of ∼40° and a twist angle of…”
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The RNA Polymerase α Subunit Recognizes the DNA Shape of the Upstream Promoter Element
Published in Biochemistry (Easton) (08-12-2020)“…We demonstrate here that the α subunit C-terminal domain of Escherichia coli RNA polymerase (αCTD) recognizes the upstream promoter (UP) DNA element via its…”
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Deucravacitinib in Moderate to Severe Psoriasis: Clinical and Quality-of-Life Outcomes in a Phase 2 Trial
Published in Dermatology and therapy (01-02-2022)“…Introduction Deucravacitinib is an oral, selective tyrosine kinase 2 inhibitor that demonstrated therapeutic benefit in a Phase 2 clinical trial of adults with…”
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Daclatasvir and sofosbuvir treatment of decompensated liver disease or post‐liver transplant hepatitis C virus recurrence in patients with advanced liver disease/cirrhosis in a real‐world cohort
Published in Hepatology communications (01-04-2018)“…We report the findings of an early access program providing treatment for chronic hepatitis C virus infection (any genotype) with daclatasvir and sofosbuvir…”
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Fusion between Retinal Rod Outer Segment Membranes and Model Membranes: A Role for Photoreceptor Peripherin/rds
Published in Biochemistry (Easton) (30-06-1998)“…Peripherin/rds plays an essential role in the maintenance of photoreceptor rod cell disk membrane structure. The purification of this protein to homogeneity…”
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A peptide analogue to a fusion domain within photoreceptor peripherin/rds promotes membrane adhesion and depolarization
Published in Biochimica et biophysica acta (15-02-2000)“…Photoreceptor peripherin/rds promotes membrane fusion, through a putative fusion domain located within the C-terminus (Boesze-Battaglia et al., Biochemistry 37…”
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X-ray crystallographic studies of transcription activation and DNA
Published 01-01-2005“…This dissertation presents the crystallographic structure determination of a quaternary transcription activation complex along with methods to improve this…”
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Dissertation