Search Results - "Napirei, M."

Impaired DNase1‐mediated degradation of neutrophil extracellular traps is associated with acute thrombotic microangiopathies by Jiménez‐Alcázar, M., Napirei, M., Panda, R., Köhler, E. C., Kremer Hovinga, J. A., Mannherz, H. G., Peine, S., Renné, T., Lämmle, B., Fuchs, T. A.

“…Summary Background Acute thrombotic microangiopathies (TMAs) are characterized by excessive microvascular thrombosis and are associated with markers of…”
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Histopathology of lupus-like nephritis in Dnase1-deficient mice in comparison to NZB/W F1 mice by Jacob, M, Napirei, M, Ricken, A, Dixkens, C, Mannherz, H G

“…Deoxyribonuclease 1 (Dnase1)-de”cient mice develop symptoms of Systemic lupus erythematosus (SLE). Here we analysed the renal histopathology of these animals…”
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Host DNases prevent vascular occlusion by neutrophil extracellular traps by Jiménez-Alcázar, Miguel, Rangaswamy, Chandini, Panda, Rachita, Bitterling, Josephine, Simsek, Yashin J., Long, Andy T., Bilyy, Rostyslav, Krenn, Veit, Renné, Christoph, Renné, Thomas, Kluge, Stefan, Panzer, Ulf, Mizuta, Ryushin, Mannherz, Hans Georg, Kitamura, Daisuke, Herrmann, Martin, Napirei, Markus, Fuchs, Tobias A.

“…Platelet and fibrin clots occlude blood vessels in hemostasis and thrombosis. Here we report a noncanonical mechanism for vascular occlusion based on…”
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Features of systemic lupus erythematosus in Dnase1-deficient mice by Möröy, Tarik, Napirei, Markus, Karsunky, Holger, Zevnik, Branko, Stephan, Harald, M annherz, Hans Georg

“…Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease that affects over one million people in the United States. SLE is characterized by…”
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Cisplatin nephrotoxicity is mediated by deoxyribonuclease I by BASNAKIAN, Alexei G, APOSTOLOV, Eugene O, XIAOYAN YIN, NAPIREI, Markus, MANNHERZ, Hans Georg, SHAH, Sudhir V

“…Cisplatin is commonly used for chemotherapy in a wide variety of tumors; however, its use is limited by kidney toxicity. Although the exact mechanism of…”
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Comparative characterization of rat deoxyribonuclease 1 (Dnase1) and murine deoxyribonuclease 1-like 3 (Dnase1l3) by Napirei, Markus, Wulf, Swantje, Eulitz, Dirk, Mannherz, Hans Georg, Kloeckl, Thomas

“…Deoxyribonuclease 1 (DNASE1, DNase I) and deoxyribonuclease 1-like 3 (DNASE1L3, DNase gamma, DNase Y, LS-DNase) are members of a DNASE1 protein family that is…”
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Deoxyribonuclease 1 aggravates acetaminophen-induced liver necrosis in male CD-1 mice by NAPIREI, Markus, BASNAKIAN, Alexei G, APOSTOLOV, Eugene O, MANNHERZ, Hans Georg

“…An overdose of acetaminophen (APAP) (N-acetyl-p-aminophenol) leads to hepatocellular necrosis induced by its metabolite N-acetyl-p-benzoquinone-imine, which is…”
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Expression pattern of the deoxyribonuclease 1 gene: lessons from the Dnase1 knockout mouse by Napirei, Markus, Ricken, Albert, Eulitz, Dirk, Knoop, Heiko, Mannherz, Hans Georg

“…The tissue distribution of deoxyribonuclease 1 (DNASE1, DNase I), a Ca2+ and Mg2+/Mn2+-dependent secretory endonuclease, has previously been investigated…”
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Chromatin breakdown by deoxyribonuclease1 promotes acetaminophen-induced liver necrosis: an ultrastructural and histochemical study on male CD-1 mice by Jacob, Monika, Mannherz, Hans Georg, Napirei, Markus

“…We analyzed in male wild-type (WT) and Dnase1 knockout (KO) CD-1 mice after acetaminophen (APAP)-intoxication the hepatolobular distribution of APAP-adducts in…”
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Systemic lupus-erythematosus: Deoxyribonuclease 1 in necrotic chromatin disposal by Napirei, Markus, Gültekin, Aykut, Kloeckl, Thomas, Möröy, Tarik, Frostegård, Johan, Mannherz, Hans Georg

“…Systemic lupus-erythematosus is an auto-immune-disease characterized by pathogenic anti-nuclear auto-antibodies. These form immune-complexes that after…”
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Loss of connexin36 increases retinal cell vulnerability to secondary cell loss by Striedinger, Katharine, Petrasch-Parwez, Elisabeth, Zoidl, Georg, Napirei, Markus, Meier, Carola, Eysel, Ulf T., Dermietzel, Rolf

“…Accruing evidence indicates that gap junctions are involved in neuronal survival after brain injury. The present study was aimed at clarifying the contribution…”
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Defective degradation of neutrophil extracellular traps is associated with acute thrombotic microangiopathies by Jimenez-Alcazar, M, Napirei, M, Panda, R, Kohler, ECM, Hovinga, JK, Mannherz, HG, Peine, S, Renne, T, Lammle, B, Fuchs, TA

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Is the retina affected in Huntington disease? by Petrasch-Parwez, Elisabeth, Saft, Carsten, Schlichting, Annegrit, Andrich, Jürgen, Napirei, Markus, Arning, Larissa, Wieczorek, Stefan, Dermietzel, Rolf, Epplen, Jörg Thomas

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Subcellular Localization and Integration Activities of Rous Sarcoma Virus Reverse Transcriptase by Werner, Susanne, Hindmarsh, Patrick, Napirei, Markus, Vogel-Bachmayr, Karin, Wöhrl, Birgitta M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Chromatin breakdown during necrosis by serum Dnase1 and the plasminogen system by Napirei, Markus, Wulf, Swantje, Mannherz, Hans Georg

“…Objective Dnase1‐deficient mice with the 129 × C57BL/6 genetic background develop symptoms of systemic lupus erythematosus, such as high titers of antinuclear…”
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Cell-type specific activation of the polyomavirus F9-1 regulatory region in transgenic mice by NEUBAUER, A, MANITZ, M. P, NAPIREI, M, KRIPPL, B

“…To characterize the activity of the polyomavirus regulatory region, two hybrid marker genes were constructed. In the first construct, the early promoter…”
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