Search Results - "Naoyuki, O."

Regulation of the metabolism of apolipoprotein M and sphingosine 1-phosphate by hepatic PPARγ activity by Kurano, Makoto, Ikeda, Hitoshi, Iso-O, Naoyuki, Hara, Masumi, Tsukamoto, Kazuhisa, Yatomi, Yutaka

“…Apolipoprotein M (apoM) is a carrier and a modulator of sphingosine 1-phosphate (S1P), an important multifunctional bioactive lipid. Since peroxisome…”
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Plant Sterols Increased IL-6 and TNF-α Secretion from Macrophages, but to a Lesser Extent than Cholesterol by Kurano, Makoto, Iso-O, Naoyuki, Hara, Masumi, Noiri, Eisei, Koike, Kazuhiko, Kadowaki, Takashi, Tsukamoto, Kazuhisa

“…Aim: Phytosterolemia is an inherited disorder characterized by hypercholesterolemia and premature atherosclerosis, together with increased inflammatory states…”
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LXR agonist increases apoE secretion from HepG2 spheroid, together with an increased production of VLDL and apoE-rich large HDL by Kurano, Makoto, Iso-O, Naoyuki, Hara, Masumi, Ishizaka, Nobukazu, Moriya, Kyoji, Koike, Kazuhiko, Tsukamoto, Kazuhisa

“…The physiological regulation of hepatic apoE gene has not been clarified, although the expression of apoE in adipocytes and macrophages has been known to be…”
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Malaria Parasites Hijack Host Receptors From Exosomes to Capture Lipoproteins by Iso-o, Naoyuki, Komatsuya, Keisuke, Tokumasu, Fuyuki, Isoo, Noriko, Ishigaki, Tomohiro, Yasui, Hiroshi, Yotsuyanagi, Hiroshi, Hara, Masumi, Kita, Kiyoshi

“…Malaria parasites cannot multiply in host erythrocytes without cholesterol because they lack complete sterol biosynthesis systems. This suggests parasitized…”
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Modulation of lipid metabolism with the overexpression of NPC1L1 in mouse liver by Kurano, Makoto, Hara, Masumi, Tsuneyama, Koichi, Okamoto, Koji, Iso-O, Naoyuki, Matsushima, Teruhiko, Koike, Kazuhiko, Tsukamoto, Kazuhisa

“…Niemann-Pick C1-like 1 protein (NPC1L1), a transporter crucial in intestinal cholesterol absorption, is expressed in human liver but not in murine liver. To…”
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A Case of a Giant Glucagonoma with Parathyroid Hormone-related Peptide Secretion Showing an Inconsistent Postsurgical Endocrine Status by Shirai, Kiyokazu, Inoue, Izumi, Kato, Jun, Maeda, Hiroki, Moribata, Kosaku, Shingaki, Naoki, Ueda, Kazuki, Deguchi, Hisanobu, Maekita, Takao, Iguchi, Mikitaka, Yanaoka, Kimihiko, Tamai, Hideyuki, Oka, Masashi, Kawai, Manabu, Yamaue, Hiroki, Yasuoka, Hironao, Nakamura, Yasushi, Iso-O, Naoyuki, Ichinose, Masao

“…A 53-year-old woman was admitted because of a giant pancreatic tumor. Hypercalcemia and a high serum parathyroid hormone-related peptide (PTHrP) level were…”
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Role of Aberrant Iron Homeostasis in the Upregulation of Transforming Growth Factor-β1 in the Kidney of Angiotensin II-Induced Hypertensive Rats by SAITO, Kan, ISHIZAKA, Nobukazu, AIZAWA, Toru, SATA, Masataka, ISO-O, Naoyuki, NOIRI, Eisei, OHNO, Minoru, NAGAI, Ryozo

“…We have previously shown that abnormal iron metabolism might be one underlying mechanism of the renal damage observed in the angiotensin II-infused rat…”
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Regulation of SR-BI Protein Levels by Phosphorylation of Its Associated Protein, PDZK1 by Nakamura, Toshiyuki, Shibata, Norihito, Nishimoto-Shibata, Takako, Feng, Dongdong, Ikemoto, Mamoru, Motojima, Kiyoto, Naoyuki Iso-o, Tsukamoto, Kazuhisa, Tsujimoto, Masafumi, Arai, Hiroyuki, Glomset, John A.

“…Scavenger receptor class B type I (SR-BI) is a high-density lipoprotein (HDL) receptor that mediates the selective uptake of HDL cholesterol and cholesterol…”
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Human Plasma Platelet-Activating Factor Acetylhydrolase Binds to All the Murine Lipoproteins, Conferring Protection Against Oxidative Stress by Noto, Hiroshi, Hara, Masumi, Karasawa, Ken, Iso-O, Naoyuki, Satoh, Hiroaki, Togo, Masako, Hashimoto, Yoshiaki, Yamada, Yoshiji, Kosaka, Tetsuya, Kawamura, Mitsunobu, Kimura, Satoshi, Tsukamoto, Kazuhisa

“…OBJECTIVE—Plasma platelet-activating factor (PAF) acetylhydrolase (AH) is an enzyme bound with lipoproteins that degrades not only PAF but also PAF-like…”
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Isoform-Dependent Cholesterol Efflux From Macrophages by Apolipoprotein E Is Modulated by Cell Surface Proteoglycans by Hara, Masumi, Matsushima, Teruhiko, Satoh, Hiroaki, Iso-o, Naoyuki, Noto, Hiroshi, Togo, Masako, Kimura, Satoshi, Hashimoto, Yoshiaki, Tsukamoto, Kazuhisa

“…OBJECTIVE—Apolipoprotein E (apoE) mediates cellular cholesterol efflux and plays a crucial role in the inhibition of atherogenesis. We investigated whether…”
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Role of aberrant iron homeostasis in the upregulation of transforming growth factor-beta1 in the kidney of angiotensin II-induced hypertensive rats by Saito, Kan, Ishizaka, Nobukazu, Aizawa, Toru, Sata, Masataka, Iso-O, Naoyuki, Noiri, Eisei, Ohno, Minoru, Nagai, Ryozo

“…We have previously shown that abnormal iron metabolism might be one underlying mechanism of the renal damage observed in the angiotensin II-infused rat…”
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Abstract 243: Familial Hypercholesterolemia Screening at a Large Corporate Clinic in Japan by Hara, Masumi, Iso-O, Naoyuki, Sugiura, Anna, Takai, Atsuko, Takeuchi, Hideyuki, Hara, Sonoka, Yamada, Takaharu, Ito, Seigo, Tsukamoto, Kazuhisa

“…Abstract only Background and Aims: Familial hypercholesterolemia (FH) is a high risk of developing premature coronary artery disease even in heterozygotes. It…”
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Thiazolidinediones Enhance Sodium-Coupled Bicarbonate Absorption from Renal Proximal Tubules via PPARγ-Dependent Nongenomic Signaling by Endo, Yoko, Suzuki, Masashi, Yamada, Hideomi, Horita, Shoko, Kunimi, Motoei, Yamazaki, Osamu, Shirai, Ayumi, Nakamura, Motonobu, Iso-O, Naoyuki, Li, Yuehong, Hara, Masumi, Tsukamoto, Kazuhisa, Moriyama, Nobuo, Kudo, Akihiko, Kawakami, Hayato, Yamauchi, Toshimasa, Kubota, Naoto, Kadowaki, Takashi, Kume, Haruki, Enomoto, Yutaka, Homma, Yukio, Seki, George, Fujita, Toshiro

“…Thiazolidinediones (TZDs) improve insulin resistance by activating a nuclear hormone receptor, peroxisome proliferator-activated receptor γ (PPARγ). However,…”
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Localization of Na+-HCO-3 cotransporter (NBC-1) variants in rat and human pancreas by Satoh, Hiroaki, Moriyama, Nobuo, Hara, Chiaki, Yamada, Hideomi, Horita, Shoko, Kunimi, Motoei, Tsukamoto, Kazuhisa, Iso-O, Naoyuki, Inatomi, Jun, Kawakami, Hayato, Kudo, Akihiko, Endou, Hitoshi, Igarashi, Takashi, Goto, Atsuo, Fujita, Toshiro, Seki, George

“…Mutations in Na(+)-HCO(3)(-) cotransporter (NBC-1) cause proximal renal tubular acidosis (pRTA) associated with ocular abnormalities. One pRTA patient had…”
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Identification of a novel mutation for phytosterolemia. Genetic analyses of 2 cases by Togo, Masako, Hashimoto, Yoshiaki, Iso-O, Naoyuki, Kurano, Makoto, Hara, Masumi, Kadowaki, Takashi, Koike, Kazuhiko, Tsukamoto, Kazuhisa

“…Phytosterolemia is one of the genetic disorders causing hypercholesterolemia and atherosclerosis together with the accumulation of plant sterol in plasma and…”
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Facilitated angiogenesis induced by heme oxygenase-1 gene transfer in a rat model of hindlimb ischemia by Suzuki, Masatoshi, Iso-o, Naoyuki, Takeshita, Satoshi, Tsukamoto, Kazuhisa, Mori, Ichiro, Sato, Tomohide, Ohno, Minoru, Nagai, Ryozo, Ishizaka, Nobukazu

“…Heme oxygenase-1 (HO-1) is an inducible form of heme oxygenase that catabolizes heme to carbon monoxide, biliverdin, and ferrous iron. We have investigated…”
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Differential effects of apolipoprotein E isoforms on lipolysis of very low-density lipoprotein triglycerides by Hara, Masumi, Iso-O, Naoyuki, Satoh, Hiroaki, Noto, Hiroshi, Togo, Masako, Ishibashi, Shun, Kimura, Satoshi, Kadowaki, Takashi, Hashimoto, Yoshiaki, Tsukamoto, Kazuhisa

“…Apolipoprotein (apo) E plays a key role in lipoprotein metabolism and has been proposed to modulate triglyceride (TG) lipolysis. However, no systematic…”
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Modulation of HDL metabolism by probucol in complete cholesteryl ester transfer protein deficiency by Noto, Hiroshi, Kawamura, Mitsunobu, Hashimoto, Yoshiaki, Satoh, Hiroaki, Hara, Masumi, Iso-o, Naoyuki, Togo, Masako, Kimura, Satoshi, Tsukamoto, Kazuhisa

“…Probucol, an antioxidative and hypolipidemic agent, has been postulated to increase reverse cholesterol transport by enhancing cholesteryl ester transfer…”
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Iron chelation and a free radical scavenger suppress angiotensin II-induced upregulation of TGF-beta1 in the heart by Saito, Kan, Ishizaka, Nobukazu, Aizawa, Toru, Sata, Masataka, Iso-o, Naoyuki, Noiri, Eisei, Mori, Ichiro, Ohno, Minoru, Nagai, Ryozo

“…Long-term administration of angiotensin II causes myocardial loss and cardiac fibrosis. We previously found iron deposition in the heart of the angiotensin…”
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Adenovirus-Mediated Gene Transfer and Lipoprotein-Mediated Protein Delivery of Plasma PAF-AH Ameliorates Proteinuria in Rat Model of Glomerulosclerosis by Iso-O, Naoyuki, Noto, Hiroshi, Hara, Masumi, Togo, Masako, Karasawa, Ken, Ohashi, Noriko, Noiri, Eisei, Hashimoto, Yoshiaki, Kadowaki, Takashi, Kimura, Satoshi, Watanabe, Tsuyoshi, Tsukamoto, Kazuhisa

“…Oxidative stress has been proposed to play a crucial role in glomerulosclerosis, although its in vivo demonstration has proved taxing given the difficulty of…”
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