Search Results - "Naoya Onohara"

TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy by Onohara, Naoya, Nishida, Motohiro, Inoue, Ryuji, Kobayashi, Hiroyuki, Sumimoto, Hideki, Sato, Yoji, Mori, Yasuo, Nagao, Taku, Kurose, Hitoshi

“…Angiotensin (Ang) II participates in the pathogenesis of heart failure through induction of cardiac hypertrophy. Ang II‐induced hypertrophic growth of…”
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A high-affinity monoclonal antibody against the FLAG tag useful for G-protein-coupled receptor study by Sasaki, Fumiyuki, Okuno, Toshiaki, Saeki, Kazuko, Min, Liu, Onohara, Naoya, Kato, Haruyasu, Shimizu, Takao, Yokomizo, Takehiko

“…The FLAG sequence (DYKDDDDK) is an artificial sequence widely used to detect, quantify, and purify proteins expressed as FLAG–fusion proteins. Several highly…”
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Gα12/13-mediated Production of Reactive Oxygen Species Is Critical for Angiotensin Receptor-induced NFAT Activation in Cardiac Fibroblasts by Fujii, Tomomi, Onohara, Naoya, Maruyama, Yoshiko, Tanabe, Shihori, Kobayashi, Hiroyuki, Fukutomi, Masashi, Nagamatsu, Yuichi, Nishihara, Naoki, Inoue, Ryuji, Sumimoto, Hideki, Shibasaki, Futoshi, Nagao, Taku, Nishida, Motohiro, Kurose, Hitoshi

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Heterotrimeric G Protein Gα13-Induced Induction of Cytokine mRNAs Through Two Distinct Pathways in Cardiac Fibroblasts by Nagamatsu, Yuichi, Nishida, Motohiro, Onohara, Naoya, Fukutomi, Masashi, Maruyama, Yoshiko, Kobayashi, Hiroyuki, Sato, Yoji, Kurose, Hitoshi

“…Overexpression of constitutively active (CA)-Gα13 significantly increased the expression of interleukin (IL)-1β and IL-6 mRNAs and proteins in rat cardiac…”
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P2-112 Inhibition of angiotensin II signaling by ATP-induced NFAT activation in cardiac fibroblasts by Reiko Suda, Naoya Onohara, Yoji Sato, Motohiro Nishida, Hitoshi Kurose

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P2L-21 A small GTPase rac mediates pertussis toxin-induced up-regulation of angiotensin receptors by Motohiro Nishida, Reiko Suda, Yoji Sato, Naoya Onohara, Shihori Tanabe, Michio Nakaya, Hitoshi Kurose

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O3F3-4 G protein β γ subunit is critical for ATP-induced NFAT activation in cardiac fibroblasts by Reiko Suda, Naoya Onohara, Motohiro Nishida, Hitoshi Kurose

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E2F2-4 Inhibition of adriamycin-induced cardiotoxicity by a CL- channel inhibitor by Aya Uemura, Motohiro Nishida, Michio Nakaya, Sachiyo Horie, Naoya Onohara, Takahisa Yano, Yoshinori Itoh, Ryozo Oishi, Hitoshi Kurose

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P3-146 Role of G α 12/13 in angiotensin II-induced cardiac fibrosis in mice by Yusuke Narita, Naoya Onohara, Motohiro Nishida, Yoji Sato, Taku Nagao, Hitoshi Kurose

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P2-107 Protection from adriamycin-induced cardiotoxicity by Cl- channel blockers by Sachiyo Horie, Motohiro Nishida, Naoya Onohara, Takahisa Yano, Yoshinori Itoh, Ryozo Oishi, Hitoshi Kuruse

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E2H6-2 TRPC3 and TRPC6 are essential for angiotensin II-induced cardiomyocyte hypertrophy by Motohiro Nishida, Naoya Onohara, Ryuji Inoue, Hideki Sumimoto, Yoji Sato, Yasuo Mori, Taku Nagao, Hitoshi Kurose

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Gα12/13-mediated Up-regulation of TRPC6 Negatively Regulates Endothelin-1-induced Cardiac Myofibroblast Formation and Collagen Synthesis through Nuclear Factor of Activated T Cells Activation by Nishida, Motohiro, Onohara, Naoya, Sato, Yoji, Suda, Reiko, Ogushi, Mariko, Tanabe, Shihori, Inoue, Ryuji, Mori, Yasuo, Kurose, Hitoshi

“…Sustained elevation of [Ca2+]i has been implicated in many cellular events. We previously reported that α subunits of G12 family G proteins (Gα12/13)…”
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Pertussis Toxin Up-regulates Angiotensin Type 1 Receptors through Toll-like Receptor 4-mediated Rac Activation by Nishida, Motohiro, Suda, Reiko, Nagamatsu, Yuichi, Tanabe, Shihori, Onohara, Naoya, Nakaya, Michio, Kanaho, Yasunori, Shibata, Takahiro, Uchida, Koji, Sumimoto, Hideki, Sato, Yoji, Kurose, Hitoshi

“…Pertussis toxin (PTX) is recognized as a specific tool that uncouples receptors from Gi and Go through ADP-ribosylation. During the study analyzing the effects…”
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Gα13 –TRPC6–NFAT signaling pathway negatively regulates cardiac myofibroblast formation by Nishida, Motohiro, Onohara, Naoya, Kurose, Hitoshi

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Diacylglycerol-mediated Ca 2+ influx through TRPC3/6 is essential for angiotensin II-induced cardiac hypertrophy by Nishida, Motohiro, Onohara, Naoya, Kurose, Hitoshi

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Galpha12/13-mediated up-regulation of TRPC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through nuclear factor of activated T cells activation by Nishida, Motohiro, Onohara, Naoya, Sato, Yoji, Suda, Reiko, Ogushi, Mariko, Tanabe, Shihori, Inoue, Ryuji, Mori, Yasuo, Kurose, Hitoshi

“…Sustained elevation of [Ca(2+)](i) has been implicated in many cellular events. We previously reported that alpha subunits of G(12) family G proteins…”
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Gα12/13-mediated Up-regulation of TRPC6 Negatively Regulates Endothelin-1-induced Cardiac Myofibroblast Formation and Collagen Synthesis through Nuclear Factor of Activated T Cells Activation by Motohiro Nishida, Naoya Onohara, Yoji Sato, Reiko Suda, Mariko Ogushi, Shihori Tanabe, Ryuji Inoue, Yasuo Mori, Hitoshi Kurose

“…Sustained elevation of [Ca 2+ ] i has been implicated in many cellular events. We previously reported that α subunits of G 12 family G proteins (Gα 12/13 )…”
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G alpha 12/13-mediated Up-regulation of TRPC6 Negatively Regulates Endothelin-1-induced Cardiac Myofibroblast Formation and Collagen Synthesis through Nuclear Factor of Activated T Cells Activation by Nishida, Motohiro, Onohara, Naoya, Sato, Yoji, Suda, Reiko, Ogushi, Mariko, Tanabe, Shihori, Inoue, Ryuji, Mori, Yasuo, Kurose, Hitoshi

“…Sustained elevation of [Ca super(2+)] sub(i) has been implicated in many cellular events. We previously reported that alpha subunits of G sub(12) family G…”
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Heterotrimeric G protein G alpha13-induced induction of cytokine mRNAs through two distinct pathways in cardiac fibroblasts by Nagamatsu, Yuichi, Nishida, Motohiro, Onohara, Naoya, Fukutomi, Masashi, Maruyama, Yoshiko, Kobayashi, Hiroyuki, Sato, Yoji, Kurose, Hitoshi

“…Overexpression of constitutively active (CA)-G alpha13 significantly increased the expression of interleukin (IL)-1beta and IL-6 mRNAs and proteins in rat…”
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Gα12/13-mediated Production of Reactive Oxygen Species Is Critical for Angiotensin Receptor-induced NFAT Activation in Cardiac Fibroblasts by Tomomi Fujii, Naoya Onohara, Yoshiko Maruyama, Shihori Tanabe, Hiroyuki Kobayashi, Masashi Fukutomi, Yuichi Nagamatsu, Naoki Nishihara, Ryuji Inoue, Hideki Sumimoto, Futoshi Shibasaki, Taku Nagao, Motohiro Nishida, Hitoshi Kurose

“…Angiotensin II (Ang II) activates multiple signaling pathways leading to hyperplasia of cardiac fibroblasts. Reactive oxygen species (ROS) produced by Ang II…”
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