Search Results - "Naoko Ito"
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Gut dysbiosis breaks immunological tolerance toward the central nervous system during young adulthood
Published in Proceedings of the National Academy of Sciences - PNAS (31-10-2017)“…Multiple sclerosis (MS) is an autoimmune disease targeting the central nervous system (CNS) mainly in young adults, and a breakage of immune tolerance to CNS…”
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2
Characterization of FLOWERING LOCUS C Homologs in Apple as a Model for Fruit Trees
Published in International journal of molecular sciences (26-06-2020)“…To elucidate the molecular mechanism of juvenility and annual flowering of fruit trees, ( ), an integrator of flowering signals, was investigated in apple as a…”
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3
C3 glomerulopathy and current dilemmas
Published in Clinical and experimental nephrology (01-08-2017)“…C3 glomerulopathy (C3G) is a recently identified disease entity caused by dysregulation of the alternative complement pathway, and dense deposit disease (DDD)…”
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4
Fecal Lcn-2 level is a sensitive biological indicator for gut dysbiosis and intestinal inflammation in multiple sclerosis
Published in Frontiers in immunology (21-10-2022)“…Multiple Sclerosis (MS) has been reported to be associated with intestinal inflammation and gut dysbiosis. To elucidate the underlying biology of MS-linked gut…”
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5
Transformation of lipid bodies related to hydrocarbon accumulation in a green alga, Botryococcus braunii (Race B)
Published in PloS one (05-12-2013)“…The colonial microalga Botryococcus braunii accumulates large quantities of hydrocarbons mainly in the extracellular space; most other oleaginous microalgae…”
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6
A case of neuroendocrine carcinoma with massive invasion to the liver and multiorgan causing acute liver failure
Published in Clinical journal of gastroenterology (01-08-2023)“…Introduction Acute liver failure (ALF) due to a malignant neoplasm is rare. Here, we present a case of neuroendocrine carcinoma (NEC) with massive invasion to…”
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Early treatment with anti-VLA-4 mAb can prevent the infiltration and/or development of pathogenic CD11b+CD4+ T cells in the CNS during progressive EAE
Published in PloS one (04-06-2014)“…Natalizumab is a humanized monoclonal antibody against the leukocyte adhesion molecule very late antigen (VLA)-4, and is currently an approved therapy for…”
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8
PLA2R-positive membranous nephropathy in IgG4-related disease
Published in BMC nephrology (23-02-2024)“…IgG4-related disease (IgG4-RD) is a fibroinflammatory disease that affects multiple organs, including the pancreas, lacrimal glands, salivary glands,…”
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Laparoscopic left lateral sectionectomy as a training procedure for surgeons learning laparoscopic hepatectomy
Published in Journal of hepato-biliary-pancreatic sciences (01-06-2013)“…Background Laparoscopic liver resection remains limited to a relatively small number of institutions because of insufficient hepatic and laparoscopic surgical…”
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10
Fragmented QRS on electrocardiography as a predictor for diastolic cardiac dysfunction in type 2 diabetes
Published in Journal of diabetes investigation (01-06-2022)“…Aims/Introduction Diastolic cardiac dysfunction in type 2 diabetes (DD2D) is a critical risk of heart failure with preserved ejection fraction. However, there…”
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11
Longitudinal study of physical activity using an accelerometer in Japanese pregnant women
Published in Japan journal of nursing science : JJNS (01-04-2020)“…Aim To describe the characteristics of objectively measured physical activity (PA) during the 2nd and 3rd trimesters of pregnancy using a accelerometer…”
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12
Clinically diverse phenotypes and genotypes of patients with branchio-oto-renal syndrome
Published in Journal of human genetics (01-05-2018)“…Branchio-oto-renal (BOR) syndrome is a rare autosomal dominant disorder characterized by branchiogenic anomalies, hearing loss, and renal anomalies. The aim of…”
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13
Myelin basic protein-specific TCR/HLA-DRB501:01 transgenic mice support the etiologic role of DRB501:01 in multiple sclerosis
Published in The Journal of immunology (1950) (15-09-2012)“…Genetic susceptibility to multiple sclerosis (MS) has been linked to the HLA-DR15 haplotype consisting of DRB1*15:01(DR2b) and DRB5*01:01(DR2a) alleles. Given…”
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14
Comfort with Motherhood in Late Pregnancy Facilitates Maternal Role Attainment in Early Postpartum
Published in The Tohoku Journal of Experimental Medicine (2015)“…Quality of life, comfort, and wellbeing during pregnancy are essential for every country in the world. Pregnancy is considered a preparation period for…”
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15
Factors Associated with Refraining from Health Checkups during the COVID-19 Pandemic in Japan
Published in Healthcare (Basel) (24-08-2023)“…This study aimed to determine the characteristics of people who refrained from having regular checkups due to the spread of the novel coronavirus 2019…”
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16
Effect of switching glatiramer acetate formulation from 20 mg daily to 40 mg three times weekly on immune function in multiple sclerosis
Published in Multiple sclerosis journal - experimental, translational and clinical (01-07-2021)“…Background Many RRMS patients who had been treated for over 20 years with GA 20 mg/ml daily (GA20) switched to 40 mg/ml three times-a-week (GA40) to reduce…”
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Surface Layer Protein A Expressed in Clostridioides difficile DJNS06-36 Possesses an Encephalitogenic Mimotope of Myelin Basic Protein
Published in Microorganisms (Basel) (24-12-2020)“…Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Recent studies suggest that migration of Th1 and Th17…”
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18
Investigations of IgG4-related disease involving the skin
Published in Modern rheumatology (01-09-2013)“…Abstract Objectives IgG4-related skin disease is not widely recognized. This prompted us to investigate the clinical and pathological features of five patients…”
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Efficacy and safety of eculizumab in childhood atypical hemolytic uremic syndrome in Japan
Published in Clinical and experimental nephrology (01-04-2016)“…Background Atypical hemolytic uremic syndrome (aHUS) is a severe life-threatening disease with frequent progression to end-stage renal disease (ESRD)…”
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Diastolic Cardiac Function Improvement by Liraglutide Is Mainly Body Weight Reduction Dependent but Independently Contributes to B-Type Natriuretic Peptide Reduction in Patients with Type 2 Diabetes with Preserved Ejection Fraction
Published in Journal of diabetes research (2021)“…Objectives. A single-arm prospective study was conducted among Japanese patients with type 2 diabetes having preserved ejection fraction. The aim was to…”
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