Search Results - "Naoki Tani"

MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells by Ishiguro, Kei-ichiro, Matsuura, Kumi, Tani, Naoki, Takeda, Naoki, Usuki, Shingo, Yamane, Mariko, Sugimoto, Michihiko, Fujimura, Sayoko, Hosokawa, Mihoko, Chuma, Shinichiro, Ko, Minoru S.H., Araki, Kimi, Niwa, Hitoshi

“…The mechanisms regulating meiotic initiation in mammals are enigmatic. It is known that retinoic acid (RA) signaling plays a pivotal role during meiotic…”
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Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial by Palfi, Stéphane, Prof, Gurruchaga, Jean Marc, MD, Ralph, G Scott, PhD, Lepetit, Helene, PhD, Lavisse, Sonia, PhD, Buttery, Philip C, PhD, Watts, Colin, PhD, Miskin, James, PhD, Kelleher, Michelle, PhD, Deeley, Sarah, MSc, Iwamuro, Hirokazu, MD, Lefaucheur, Jean Pascal, MD, Thiriez, Claire, MD, Fenelon, Gilles, MD, Lucas, Cherry, BA, Brugières, Pierre, MD, Gabriel, Inanna, MD, Abhay, Kou, MD, Drouot, Xavier, MD, Tani, Naoki, MD, Kas, Aurelie, MD, Ghaleh, Bijan, Prof, Le Corvoisier, Philippe, MD, Dolphin, Patrice, MSc, Breen, David P, MRCP, Mason, Sarah, BSc, Guzman, Natalie Valle, MSc, Mazarakis, Nicholas D, Prof, Radcliffe, Pippa A, PhD, Harrop, Richard, PhD, Kingsman, Susan M, PhD, Rascol, Olivier, Prof, Naylor, Stuart, PhD, Barker, Roger A, Prof, Hantraye, Philippe, PhD, Remy, Philippe, Prof, Cesaro, Pierre, Prof, Mitrophanous, Kyriacos A, PhD

“…Summary Background Parkinson's disease is typically treated with oral dopamine replacement therapies; however, long-term treatment leads to motor complications…”
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PKA Regulates PINK1 Stability and Parkin Recruitment to Damaged Mitochondria through Phosphorylation of MIC60 by Akabane, Shiori, Uno, Midori, Tani, Naoki, Shimazaki, Shunta, Ebara, Natsumi, Kato, Hiroki, Kosako, Hidetaka, Oka, Toshihiko

“…A mitochondrial kinase, PTEN-induced putative kinase 1 (PINK1), selectively recruits the ubiquitin ligase Parkin to damaged mitochondria, which modifies…”
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Characteristics of Pain During MRI-Guided Focused Ultrasound Thalamotomy by He, Xin, Oshino, Satoru, Hosomi, Koichi, Kanemoto, Manabu, Tani, Naoki, Kishima, Haruhiko

“…Magnetic resonance imaging-guided focused ultrasound (MRgFUS) has become popular as an incisionless mode of neurosurgical treatment. However, head pain during…”
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PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria by Okatsu, Kei, Oka, Toshihiko, Iguchi, Masahiro, Imamura, Kenji, Kosako, Hidetaka, Tani, Naoki, Kimura, Mayumi, Go, Etsu, Koyano, Fumika, Funayama, Manabu, Shiba-Fukushima, Kahori, Sato, Shigeto, Shimizu, Hideaki, Fukunaga, Yuko, Taniguchi, Hisaaki, Komatsu, Masaaki, Hattori, Nobutaka, Mihara, Katsuyoshi, Tanaka, Keiji, Matsuda, Noriyuki

“…Dysfunction of PINK1, a mitochondrial Ser/Thr kinase, causes familial Parkinson's disease (PD). Recent studies have revealed that PINK1 is rapidly degraded in…”
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Phase-amplitude coupling between infraslow and high-frequency activities well discriminates between the preictal and interictal states by Hashimoto, Hiroaki, Khoo, Hui Ming, Yanagisawa, Takufumi, Tani, Naoki, Oshino, Satoru, Kishima, Haruhiko, Hirata, Masayuki

“…Infraslow activity (ISA) and high-frequency activity (HFA) are key biomarkers for studying epileptic seizures. We aimed to elucidate the relationship between…”
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Technical Aspects of SEEG and Its Interpretation in the Delineation of the Epileptogenic Zone by KHOO, Hui Ming, HALL, Jeffery A., DUBEAU, Francois, TANI, Naoki, OSHINO, Satoru, FUJITA, Yuya, GOTMAN, Jean, KISHIMA, Haruhiko

“…Stereo-electroencephalography (SEEG) has gained global popularity in recent years. In Japan, a country in which invasive studies using subdural electrodes…”
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Loss of the transcription repressor ZHX3 induces senescence-associated gene expression and mitochondrial-nucleolar activation by Igata, Tomoka, Tanaka, Hiroshi, Etoh, Kan, Hong, Seonghyeon, Tani, Naoki, Koga, Tomoaki, Nakao, Mitsuyoshi

“…Cellular senescence is accompanied by metabolic and epigenomic remodeling, but the transcriptional mechanism of this process is unclear. Our previous RNA…”
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Clinical Factors Related to Outcomes in Pediatric Epilepsy Surgery: Insight into Predictors of Poor Surgical Outcome by OSHINO, Satoru, TANI, Naoki, KHOO, Hui Ming, KAGITANI-SHIMONO, Kuriko, NABATAME, Shin, TOMINAGA, Koji, YANAGISAWA, Takufumi, HIRATA, Masayuki, KISHIMA, Haruhiko

“…Successful surgery for drug-resistant pediatric epilepsy can facilitate motor and cognitive development and improve quality of life by resolution or reduction…”
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Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis by Horisawa-Takada, Yuki, Kodera, Chisato, Takemoto, Kazumasa, Sakashita, Akihiko, Horisawa, Kenichi, Maeda, Ryo, Shimada, Ryuki, Usuki, Shingo, Fujimura, Sayoko, Tani, Naoki, Matsuura, Kumi, Akiyama, Tomohiko, Suzuki, Atsushi, Niwa, Hitoshi, Tachibana, Makoto, Ohba, Takashi, Katabuchi, Hidetaka, Namekawa, Satoshi H., Araki, Kimi, Ishiguro, Kei-Ichiro

“…During spermatogenesis, meiosis is accompanied by a robust alteration in gene expression and chromatin status. However, it remains elusive how the meiotic…”
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Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans by Iwata, Takamitsu, Yanagisawa, Takufumi, Ikegaya, Yuji, Smallwood, Jonathan, Fukuma, Ryohei, Oshino, Satoru, Tani, Naoki, Khoo, Hui Ming, Kishima, Haruhiko

“…Core features of human cognition highlight the importance of the capacity to focus on information distinct from events in the here and now, such as mind…”
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Receptor-mediated yolk uptake is required for oskar mRNA localization and cortical anchorage of germ plasm components in the Drosophila oocyte by Tanaka, Tsubasa, Tani, Naoki, Nakamura, Akira

“…The Drosophila germ plasm is responsible for germ cell formation. Its assembly begins with localization of oskar mRNA to the posterior pole of the oocyte. The…”
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Meiotic cohesins mediate initial loading of HORMAD1 to the chromosomes and coordinate SC formation during meiotic prophase by Fujiwara, Yasuhiro, Horisawa-Takada, Yuki, Inoue, Erina, Tani, Naoki, Shibuya, Hiroki, Fujimura, Sayoko, Kariyazono, Ryo, Sakata, Toyonori, Ohta, Kunihiro, Araki, Kimi, Okada, Yuki, Ishiguro, Kei-Ichiro

“…During meiotic prophase, sister chromatids are organized into axial element (AE), which underlies the structural framework for the meiotic events such as…”
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Small temperature variations are a key regulator of reproductive growth and assimilate storage in oil palm (Elaeis guineensis) by Tani, Naoki, Abdul Hamid, Zubaidah Aimi, Joseph, Natra, Sulaiman, Othman, Hashim, Rokiah, Arai, Takamitsu, Satake, Akiko, Kondo, Toshiaki, Kosugi, Akihiko

“…Oil palm is an important crop for global vegetable oil production, and is widely grown in the humid tropical regions of Southeast Asia. Projected future…”
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Magnetoencephalography detects phase-amplitude coupling in Parkinson’s disease by Tanaka, Masataka, Yanagisawa, Takufumi, Fukuma, Ryohei, Tani, Naoki, Oshino, Satoru, Mihara, Masahito, Hattori, Noriaki, Kajiyama, Yuta, Hashimoto, Ryota, Ikeda, Manabu, Mochizuki, Hideki, Kishima, Haruhiko

“…To characterize Parkinson’s disease, abnormal phase-amplitude coupling is assessed in the cortico-basal circuit using invasive recordings. It is unknown…”
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Risk Factors for Postoperative Delirium After Deep Brain Stimulation Surgery for Parkinson Disease by Tanaka, Masataka, Tani, Naoki, Maruo, Tomoyuki, Oshino, Satoru, Hosomi, Koichi, Saitoh, Youichi, Kishima, Haruhiko

“…The aim of this study was to investigate the incidence of and risk factors for postoperative delirium (POD) after deep brain stimulation (DBS) surgery in…”
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Meiosis-Specific C19orf57/4930432K21Rik/BRME1 Modulates Localization of RAD51 and DMC1 to DSBs in Mouse Meiotic Recombination by Takemoto, Kazumasa, Tani, Naoki, Takada-Horisawa, Yuki, Fujimura, Sayoko, Tanno, Nobuhiro, Yamane, Mariko, Okamura, Kaho, Sugimoto, Michihiko, Araki, Kimi, Ishiguro, Kei-ichiro

“…Meiotic recombination is critical for genetic exchange and generation of chiasmata that ensures faithful chromosome segregation during meiosis I. Meiotic…”
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An Immunocompetent Case of Capnocytophaga canimorsus Infection Complicated by Secondary Thrombotic Microangiopathy and Disseminated Intravascular Coagulation by Tani, Naoki, Nakamura, Keiji, Sumida, Kosuke, Suzuki, Michio, Imaoka, Koichi, Shimono, Nobuyuki

“…A 62-year-old woman with no previous history developed a Capnocytophaga canimorsus infection followed by thrombotic microangiopathy (TMA) and disseminated…”
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Comparing modeling methods of genomic prediction for growth traits of a tropical timber species, Shorea macrophylla by Akutsu, Haruto, Na’iem, Mohammad, Widiyatno, Indrioko, Sapto, Sawitri, Purnomo, Susilo, Uchiyama, Kentaro, Tsumura, Yoshihiko, Tani, Naoki

“…IntroductionShorea macrophylla is a commercially important tropical tree species grown for timber and oil. It is amenable to plantation forestry due to its…”
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Mettl1-dependent m7G tRNA modification is essential for maintaining spermatogenesis and fertility in Drosophila melanogaster by Kaneko, Shunya, Miyoshi, Keita, Tomuro, Kotaro, Terauchi, Makoto, Tanaka, Ryoya, Kondo, Shu, Tani, Naoki, Ishiguro, Kei-Ichiro, Toyoda, Atsushi, Kamikouchi, Azusa, Noguchi, Hideki, Iwasaki, Shintaro, Saito, Kuniaki

“…Modification of guanosine to N 7 -methylguanosine (m 7 G) in the variable loop region of tRNA is catalyzed by the METTL1/WDR4 heterodimer and stabilizes target…”
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