Search Results - "Nano, Jana"
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The role of epigenetic modifications in neurodevelopmental disorders: A systematic review
Published in Neuroscience and biobehavioral reviews (01-11-2018)“…•Epigenetic modifications play a role in neurodevelopment.•Few epigenetic markers have been repeatedly identified in relation to ASD or ADHD.•Suboptimal…”
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The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review
Published in PloS one (14-12-2016)“…Epigenetic modifications of the genome, such as DNA methylation and histone modifications, have been reported to play a role in neurodegenerative diseases (ND)…”
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3
Proteomic profiling of longitudinal changes in kidney function among middle-aged and older men and women: the KORA S4/F4/FF4 study
Published in BMC medicine (05-07-2023)“…Due to the asymptomatic nature of the early stages, chronic kidney disease (CKD) is usually diagnosed at late stages and lacks targeted therapy, highlighting…”
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Obesity and Life Expectancy with and without Diabetes in Adults Aged 55 Years and Older in the Netherlands: A Prospective Cohort Study
Published in PLoS medicine (19-07-2016)“…Overweight and obesity are associated with increased risk of type 2 diabetes. Limited evidence exists regarding the effect of excess weight on years lived with…”
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Epigenetic Link Between Statin Therapy and Type 2 Diabetes
Published in Diabetes care (01-04-2020)“…To investigate the role of epigenetics in statins' diabetogenic effect comparing DNA methylation (DNAm) between statin users and nonusers in an epigenome-wide…”
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The impact of fractionation on secondary malignancies in postoperative breast cancer irradiation
Published in Breast (Edinburgh) (01-12-2024)“…Randomized studies demonstrated the oncological equivalence of (ultra-)hypofractionation compared to a 5-week schedule in postoperative radiotherapy of breast…”
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A survey of cancer patients' interest in undertaking exercise to promote relaxation during radiotherapy for breast cancer and metastatic cancer
Published in Radiation oncology (London, England) (31-05-2024)“…Approximately 25-50% of patients undergoing radiotherapy (RT) experience psychological distress and anxiety, which can detrimentally affect both their quality…”
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The role of DNA methylation and histone modifications in blood pressure: a systematic review
Published in Journal of human hypertension (01-10-2019)“…Epigenetic mechanisms might play a role in the pathophysiology of hypertension, a major risk factor for cardiovascular disease and renal failure. We aimed to…”
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Association of sex hormones and sex hormone-binding globulin with liver fat in men and women: an observational and Mendelian randomization study
Published in Frontiers in endocrinology (Lausanne) (13-10-2023)“…Background Sex hormones and sex hormone-binding globulin (SHBG) may play a role in fatty liver development. We sought to examine the association of various…”
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The functions of estrogen receptor beta in the female brain: A systematic review
Published in Maturitas (01-11-2016)“…Highlights • Forty-nine animal studies investigating the functions of estrogen receptor beta in the female brain were included in this review. • Estrogen…”
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Associations of endogenous androgens and sex hormone-binding globulin with kidney function and chronic kidney disease
Published in Frontiers in endocrinology (Lausanne) (19-12-2022)“…The role of endogenous androgens in kidney function and disease has not been extensively explored in men and women. We analyzed data from the observational…”
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Epigenetics and Inflammatory Markers: A Systematic Review of the Current Evidence
Published in International journal of inflammation (01-01-2019)“…Epigenetic mechanisms have been suggested to play a role in the genetic regulation of pathways related to inflammation. Therefore, we aimed to systematically…”
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Incidental dose distribution to contralateral internal mammary nodes in breast cancer patients undergoing adjuvant radiotherapy
Published in Clinical and translational radiation oncology (01-09-2024)“…•Although an involvement of internal mammary lymph nodes (IMN) was found to be bilateral in up to one-third of patients, the contralateral IMN is mostly…”
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Sex hormone-binding globulin, androgens and mortality: the KORA-F4 cohort study
Published in Endocrine Connections (01-04-2020)“…Objective Sex hormone-binding globulin (SHBG) and androgens have been associated with mortality in women and men, but controversy still exists. Our objective…”
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Cross-sectional and prospective relationships of endogenous progestogens and estrogens with glucose metabolism in men and women: a KORA F4/FF4 Study
Published in BMJ open diabetes research & care (11-02-2021)“…IntroductionRelationships between endogenous female sex hormones and glycemic traits remain understudied, especially in men. We examined whether endogenous…”
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Validation of Candidate Phospholipid Biomarkers of Chronic Kidney Disease in Hyperglycemic Individuals and Their Organ-Specific Exploration in Leptin Receptor-Deficient db/db Mouse
Published in Metabolites (03-02-2021)“…Biological exploration of early biomarkers for chronic kidney disease (CKD) in (pre)diabetic individuals is crucial for personalized management of diabetes…”
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Polygenic scores for estimated glomerular filtration rate in a population of general adults and elderly - comparative results from the KORA and AugUR study
Published in BMC genetics (25-05-2023)“…Polygenic scores (PGSs) combining genetic variants found to be associated with creatinine-based estimated glomerular filtration rate (eGFR ) have been applied…”
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Association between hepatic fat and subclinical vascular disease burden in the general population
Published in BMJ open gastroenterology (30-09-2021)“…ObjectiveIt is still controversial if increased hepatic fat independently contributes to cardiovascular risk. We aimed to assess the association between…”
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Gamma-glutamyltransferase levels, prediabetes and type 2 diabetes: a Mendelian randomization study
Published in International journal of epidemiology (01-10-2017)Get full text
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An Epigenome-Wide Association Study of Obesity-Related Traits
Published in American journal of epidemiology (01-08-2018)Get full text
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