Search Results - "Nanni‐Metellus, Isabelle"

Multiplexed Droplet Digital PCR Assays for the Simultaneous Screening of Major Genetic Alterations in Tumors of the Central Nervous System by Appay, Romain, Fina, Frederic, Barets, Doriane, Gallardo, Catherine, Nanni-Metellus, Isabelle, Scavarda, Didier, Henaff, Daniel, Vincent, Juline, Grewis, Lise, Pourquier, Philippe, Colin, Carole, Figarella-Branger, Dominique

“…The increased integration of molecular alterations to define tumor type or grade in central nervous system (CNS) tumor classification brings new challenges for…”
Get full text

Droplet digital PCR is a powerful technique to demonstrate frequent FGFR1 duplication in dysembryoplastic neuroepithelial tumors by Fina, Frédéric, Barets, Doriane, Colin, Carole, Bouvier, Corinne, Padovani, Laëtitia, Nanni-Metellus, Isabelle, Ouafik, L'Houcine, Scavarda, Didier, Korshunov, Andrey, Jones, David T W, Figarella-Branger, Dominique

“…Dysembryoplastic neuroepithelial tumors (DNT) share V600E mutation in the BRAF gene with other low grade neuroepithelial tumors (LGNTs). FGFR1 internal tandem…”
Get full text

Extreme Gradient Boosting Tuned with Metaheuristic Algorithms for Predicting Myeloid NGS Onco-Somatic Variant Pathogenicity by Pellegrino, Eric, Camilla, Clara, Abbou, Norman, Beaufils, Nathalie, Pissier, Christel, Gabert, Jean, Nanni-Metellus, Isabelle, Ouafik, L'Houcine

“…The advent of next-generation sequencing (NGS) technologies has revolutionized the field of bioinformatics and genomics, particularly in the area of…”
Get full text

Evidence for BRAF V600E and H3F3A K27M double mutations in paediatric glial and glioneuronal tumours by Nguyen, Anh Tuan, Colin, Carole, Nanni-Metellus, Isabelle, Padovani, Laetitia, Maurage, Claude-Alain, Varlet, Pascale, Miquel, Catherine, Uro-Coste, Emmanuelle, Godfraind, Catherine, Lechapt-Zalcman, Emmanuelle, Labrousse, François, Gauchotte, Guillaume, Silva, Karen, Jouvet, Anne, Figarella-Branger, Dominique

Get full text

IDH mutation status impact on in vivo hypoxia biomarkers expression: new insights from a clinical, nuclear imaging and immunohistochemical study in 33 glioma patients by Metellus, Philippe, Colin, Carole, Taieb, David, Guedj, Eric, Nanni-Metellus, Isabelle, de Paula, Andre Maues, Colavolpe, Cécile, Fuentes, Stephane, Dufour, Henry, Barrie, Marylin, Chinot, Olivier, Ouafik, L’Houcine, Figarella-Branger, Dominique

“…Mutations in the gene encoding isocitrate dehydrogenase enzyme isoforms 1 ( IDH1 ) and 2 ( IDH2 ) have recently been identified in a large proportion of glial…”
Get full text

Dysembryoplastic Neuroepithelial Tumors Share with Pleomorphic Xanthoastrocytomas and Gangliogliomas BRAFV600E Mutation and Expression by Chappé, Céline, Padovani, Laetitia, Scavarda, Didier, Forest, Fabien, Nanni-Metellus, Isabelle, Loundou, Anderson, Mercurio, Sandy, Fina, Frédéric, Lena, Gabriel, Colin, Carole, Figarella-Branger, Dominique

“…Pediatric cortical glioneuronal benign tumors mainly include gangliogliomas (GG) [differential diagnoses pilocytic astrocytomas (PA) and pleomorphic…”
Get full text

A Multicenter Blinded Study Evaluating EGFR and KRAS Mutation Testing Methods in the Clinical Non–Small Cell Lung Cancer Setting—IFCT/ERMETIC2 Project Part 1 by Beau-Faller, Michèle, Blons, Hélène, Domerg, Caroline, Gajda, Dorota, Richard, Nicolas, Escande, Fabienne, Solassol, Jérôme, Denis, Marc G, Cayre, Anne, Nanni-Metellus, Isabelle, Olschwang, Sylviane, Lizard, Sarab, Piard, Fabienne, Pretet, Jean-Luc, de Fraipont, Florence, Bièche, Ivan, de Cremoux, Patricia, Rouquette, Isabelle, Bringuier, Pierre-Paul, Mosser, Jean, Legrain, Michèle, Voegeli, Anne-Claire, Saulnier, Patrick, Morin, Franck, Pignon, Jean-Pierre, Zalcman, Gérard, Cadranel, Jacques

“…Epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitors have limited use as first-line treatment for mutated EGFR metastatic non–small cell lung…”
Get full text

Dysembryoplastic neuroepithelial tumors share with pleomorphic xanthoastrocytomas and gangliogliomas BRAF(V600E) mutation and expression by Chappé, Céline, Padovani, Laetitia, Scavarda, Didier, Forest, Fabien, Nanni-Metellus, Isabelle, Loundou, Anderson, Mercurio, Sandy, Fina, Frédéric, Lena, Gabriel, Colin, Carole, Figarella-Branger, Dominique

“…Pediatric cortical glioneuronal benign tumors mainly include gangliogliomas (GG) [differential diagnoses pilocytic astrocytomas (PA) and pleomorphic…”
Get full text

Genomic analysis of paired IDHwt glioblastomas reveals recurrent alterations of MPDZ at relapse after radiotherapy and chemotherapy by Chanez, Brice, Appay, Romain, Guille, Arnaud, Lagarde, Arnaud, Colin, Carole, Adelaide, José, Denicolai, Emilie, Jiguet-Jiglaire, Carine, Bequet, Céline, Graillon, Thomas, Boissonneau, Sébastien, Nanni-Metellus, Isabelle, Dufour, Henry, Figarella-Branger, Dominique, Chinot, Olivier, Tabouret, Emeline

“…We aimed to identify genomic drivers of glioblastoma inevitable recurrence. Ten pairs of initial and recurrent frozen IDHwt glioblastoma samples were screened…”
Get full text

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study by Tomasini, Pascale, Barlesi, Fabrice, Gilles, Sophie, Nanni-Metellus, Isabelle, Soffietti, Riccardo, Denicolai, Emilie, Pellegrino, Eric, Bialecki, Emilie, Ouafik, L'Houcine, Metellus, Philippe

“…Lung cancer brain metastases (BMs) are frequent and associated with poor prognosis despite a better knowledge of lung cancer biology and the development of…”
Get full text

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study by Tomasini, Pascale, Barlesi, Fabrice, Gilles, Sophie, Nanni-Metellus, Isabelle, Soffietti, Riccardo, Denicolai, Emilie, Pellegrino, Eric, Bialecki, Emilie, Ouafik, L’houcine, Metellus, Philippe

Get full text

Differential expression of miR200a-3p and miR21 in grade II–III and grade IV gliomas: Evidence that miR200a-3p is regulated by O 6 -methylguanine methyltransferase and promotes temozolomide responsiveness by Berthois, Yolande, Delfino, Christine, Metellus, Philippe, Fina, Frederic, Nanni-Metellus, Isabelle, Al Aswy, Hayat, Pirisi, Victor, Ouafik, L’Houcine, Boudouresque, Françoise

Get full text

Plasma nanoDSF Denaturation Profile at Baseline Is Predictive of Glioblastoma EGFR Status by Eyraud, Rémi, Ayache, Stéphane, Tsvetkov, Philipp O, Kalidindi, Shanmugha Sri, Baksheeva, Viktoriia E, Boissonneau, Sébastien, Jiguet-Jiglaire, Carine, Appay, Romain, Nanni-Metellus, Isabelle, Chinot, Olivier, Devred, François, Tabouret, Emeline

“…Glioblastoma (GBM) is the most frequent and aggressive primary brain tumor in adults. Recently, we demonstrated that plasma denaturation profiles of…”
Get full text

Deep Learning Architecture Optimization with Metaheuristic Algorithms for Predicting BRCA1/BRCA2 Pathogenicity NGS Analysis by Pellegrino, Eric, Brunet, Theo, Pissier, Christel, Camilla, Clara, Abbou, Norman, Beaufils, Nathalie, Nanni-Metellus, Isabelle, Métellus, Philippe, Ouafik, L’Houcine

“…Motivation, BRCA1 and BRCA2 are genes with tumor suppressor activity. They are involved in a considerable number of biological processes. To help the biologist…”
Get full text

Genomic analysis of paired IDHwt glioblastoma (GB) to reveal recurrent alterations of MPDZ at relapse after radiotherapy and temozolomide (RTCT) by Chanez, Brice, Appay, Romain, Guille, Arnaud, Lagarde, Arnaud, Adelaide, José, Denicolai, Emilie, Campello, Chantal, Tchoghandjian, Aurelie, Petrirena, Gregorio, Colin, Carole, Barrie, Maryline, Baeza-Kallee, Nathalie, Boucard, Celine, Jiguet-Jiglaire, Carine, Graillon, Thomas, Nanni-Metellus, Isabelle, Dufour, Henry, Figarella-Branger, Dominique, Chinot, Olivier L., Tabouret, Emeline

“…Abstract only e13535 Background: GB are highly aggressive tumors which systematically relapse. Our objective was to identify disease progression mechanisms and…”
Get full text

Detection of EGFR, KRAS and BRAF mutations in metastatic cells from cerebrospinal fluid by Frankel, Diane, Nanni-Metellus, Isabelle, Robaglia-Schlupp, Andrée, Tomasini, Pascale, Guinde, Julien, Barlesi, Fabrice, Astoul, Philippe, Ouafik, L'Houcine, Amatore, Florent, Secq, Véronique, Kaspi, Elise, Roll, Patrice

“…In lung adenocarcinoma, molecular profiling of actionable genes has become essential to set up targeted therapies. However, the feasibility and the relevance…”
Get more information

Prognostic Impact of CD133 mRNA Expression in 48 Glioblastoma Patients Treated with Concomitant Radiochemotherapy: A Prospective Patient Cohort at a Single Institution by Metellus, Philippe, Nanni-Metellus, Isabelle, Delfino, Christine, Colin, Carole, Tchogandjian, Aurelie, Coulibaly, Bema, Fina, Frederic, Loundou, Anderson, Barrie, Marylin, Chinot, Olivier, Ouafik, L’Houcine, Figarella-Branger, Dominique

“…Background Cancer stem cells are thought to represent the population of tumorigenic cells responsible for tumor development. The CD133 antigen has been…”
Get full text

Differential expression of miR200a-3p and miR21 in grade II-III and grade IV gliomas: Evidence that miR200a-3p is regulated by O6-methylguanine methyltransferase and promotes temozolomide responsiveness by Berthois, Yolande, Delfino, Christine, Metellus, Philippe, Fina, Frederic, Nanni-Metellus, Isabelle, Al Aswy, Hayat, Pirisi, Victor, Ouafik, L'Houcine, Boudouresque, Françoise

“…Glioblastoma multiforme (GBM) is the most common primary brain tumor and is among the deadliest of human cancers. Dysregulation of microRNAs (miRNAs)…”
Get full text

Differential expression of miR200a-3p and miR21 in grade II–III and grade IV gliomas: Evidence that miR200a-3p is regulated by O by Berthois, Yolande, Delfino, Christine, Metellus, Philippe, Fina, Frederic, Nanni-Metellus, Isabelle, Al Aswy, Hayat, Pirisi, Victor, Ouafik, L’Houcine, Boudouresque, Françoise

“…Glioblastoma multiforme (GBM) is the most common primary brain tumor and is among the deadliest of human cancers. Dysregulation of microRNAs (miRNAs)…”
Get full text

Differential expression of miR200a-3p and miR21 in grade II–III and grade IV gliomas by Berthois, Yolande, Delfino, Christine, Metellus, Philippe, Fina, Frederic, Nanni-Metellus, Isabelle, Al Aswy, Hayat, Pirisi, Victor, Ouafik, L’houcine, Boudouresque, Françoise

Get full text