Search Results - "Nanjundaswamy, Shivananju"
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Synthesis and characterization of novel 2-amino-chromene-nitriles that target Bcl-2 in acute myeloid leukemia cell lines
Published in PloS one (30-09-2014)“…The anti-apoptotic protein Bcl-2 is a well-known and attractive therapeutic target for cancer. In the present study the solution-phase T3P-DMSO mediated…”
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Nano-Zirconium Dioxide Catalyzed Multicomponent Synthesis of Bioactive Pyranopyrazoles That Target Cyclin Dependent Kinase 1 in Human Breast Cancer Cells
Published in Biomedicines (10-01-2023)“…Small molecules are being used to inhibit cyclin dependent kinase (CDK) enzymes in cancer treatment. There is evidence that CDK is a drug-target for cancer…”
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Anti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives
Published in BMC chemical biology (03-10-2012)“…Dibenzoazepine (DB) derivatives are important and valuable compounds in medicinal chemistry. The synthesis and chemotherapeutic properties of naturally…”
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Synthesis, characterization and in vitro evaluation of novel enantiomerically-pure sulphonamide antimalarials
Published in Organic & biomolecular chemistry (01-01-2015)“…Malaria parasites are currently gaining drug-resistance rapidly, across countries and continents. Hence, the discovery and development of novel chemical…”
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