Search Results - "Nanduri, Srinivas"

Streptozotocin produces oxidative stress, inflammation and decreases BDNF concentrations to induce apoptosis of RIN5F cells and type 2 diabetes mellitus in Wistar rats by Bathina, Siresha, Srinivas, Nanduri, Das, Undurti N.

“…Neurodegenerative disorders, such as deficits in learning, memory and cognition and Alzheimer's disease are associated with diabetes mellitus. Brain-derived…”
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Targeting AMPK in Diabetes and Diabetic Complications: Energy Homeostasis, Autophagy and Mitochondrial Health by Madhavi, Y V, Gaikwad, Nikhil, Yerra, Veera Ganesh, Kalvala, Anil Kumar, Nanduri, Srinivas, Kumar, Ashutosh

“…Adenosine 5'-monophosphate activated protein kinase (AMPK) is a key enzymatic protein involved in linking the energy sensing to the metabolic manipulation. It…”
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Continued Increase of Erythromycin Nonsusceptibility and Clindamycin Nonsusceptibility Among Invasive Group A Streptococci Driven by Genomic Clusters, United States, 2018-2019 by Li, Yuan, Rivers, Joy, Mathis, Saundra, Li, Zhongya, McGee, Lesley, Chochua, Sopio, Metcalf, Benjamin J, Fleming-Dutra, Katherine E, Nanduri, Srinivas A, Beall, Bernard

“…We analyzed 9630 invasive GAS surveillance isolates in the USA. From 2015-2017 to 2018-2019, significant increases in erythromycin-nonsusceptibility (18% vs…”
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Genomic Characterization of Group A Streptococci Causing Pharyngitis and Invasive Disease in Colorado, USA, June 2016– April 2017 by Li, Yuan, Dominguez, Samuel, Nanduri, Srinivas A, Rivers, Joy, Mathis, Saundra, Li, Zhongya, McGee, Lesley, Chochua, Sopio, Metcalf, Benjamin J, Van Beneden, Chris A, Beall, Bernard, Miller, Lisa

“…Abstract Background The genomic features and transmission link of circulating Group A Streptococcus (GAS) strains causing different disease types, such as…”
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Structure based design, synthesis and evaluation of new thienopyrimidine derivatives as anti-bacterial agents by Malasala, Satyaveni, Polomoni, Anusha, Ahmad, Md. Naiyaz, Shukla, Manjulika, Kaul, Grace, Dasgupta, Arunav, Chopra, Sidharth, Nanduri, Srinivas

“…•A series of 3 different types of new fused pyrimidine derivatives has been synthesized•22 new molecules were screened against M. tuberculosis H37RV strain and…”
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Targeting DNA Gyrase to Combat Mycobacterium tuberculosis: An Update by Das, Swetarka, Garg, Tanu, Srinivas, Nanduri, Dasgupta, Arunava, Chopra, Sidharth

“…DNA gyrase is a clinically validated drug target, currently targeted only by fluoroquinolone class of antibacterials. However, owing to increasing drug…”
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Effectiveness of Pfizer-BioNTech and Moderna Vaccines in Preventing SARS-CoV-2 Infection Among Nursing Home Residents Before and During Widespread Circulation of the SARS-CoV-2 B.1.617.2 (Delta) Variant - National Healthcare Safety Network, March 1-August 1, 2021 by Nanduri, Srinivas, Pilishvili, Tamara, Derado, Gordana, Soe, Minn Minn, Dollard, Philip, Wu, Hsiu, Li, Qunna, Bagchi, Suparna, Dubendris, Heather, Link-Gelles, Ruth, Jernigan, John A, Budnitz, Daniel, Bell, Jeneita, Benin, Andrea, Shang, Nong, Edwards, Jonathan R, Verani, Jennifer R, Schrag, Stephanie J

“…Nursing home and long-term care facility residents live in congregate settings and are often elderly and frail, putting them at high risk for infection with…”
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Synthesis and biological evaluation of new 3-substituted coumarin derivatives as selective inhibitors of human carbonic anhydrase IX and XII by Mahammad Ghouse, Shaik, Bahatam, Kavyaraj, Angeli, Andrea, Pawar, Gaurav, Chinchilli, Krishna Kartheek, Yaddanapudi, Venkata Madhavi, Mohammed, Arifuddin, Supuran, Claudiu T., Nanduri, Srinivas

“…The Carbonic anhydrase isoforms IX and XII play a significant role in regulating the intracellular and extracellular pH in hypoxic tumours abetting the…”
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Synthesis and anti-plasmodial activity of isoandrographolide acetals by Tamang, Nitesh, Mavileti, Sai Kiran, Yadav, Mamta, Nanduri, Srinivas, Sahal, Dinkar, Golakoti, Nageswara Rao

“…Isoandrographolide (2) and its nineteen acetals (3a–3o, 4, 5 and 6a–6b) of which fifteen are new were synthesized and characterized using 1 H-NMR, 13 C-NMR,…”
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New 3‐(1H‐benzo[d]imidazol‐2‐yl)quinolin‐2(1H)‐one‐based triazole derivatives: Design, synthesis, and biological evaluation as antiproliferative and apoptosis‐inducing agents by Gaikwad, Nikhil B., Bansode, Sapana, Biradar, Shankar, Ban, Mayuri, Srinivas, Nanduri, Godugu, Chandraiah, Yaddanapudi, Venkata M.

“…A series of 1,2,3‐triazole derivatives based on the quinoline–benzimidazole hybrid scaffold was designed, synthesized, and screened against a panel of NCI‐60…”
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Genomic Surveillance of Streptococcus pyogenes Strains Causing Invasive Disease, United States, 2016-2017 by Li, Yuan, Rivers, Joy, Mathis, Saundra, Li, Zhongya, Velusamy, Srinivasan, Nanduri, Srinivas A, Van Beneden, Chris A, Snippes-Vagnone, Paula, Lynfield, Ruth, McGee, Lesley, Chochua, Sopio, Metcalf, Benjamin J, Beall, Bernard

“…is a major cause of severe, invasive infections in humans. The bacterial pathogen harbors a wide array of virulence factors and exhibits high genomic…”
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Challenges in Surveillance for Streptococcal Toxic Shock Syndrome: Active Bacterial Core Surveillance, United States, 2014-2017 by Nanduri, Srinivas Acharya, Onukwube, Jennifer, Apostol, Mirasol, Alden, Nisha, Petit, Susan, Farley, Monica, Harrison, Lee H., Como-Sabetti, Kathy, Smelser, Chad, Burzlaff, Kari, Cieslak, Paul, Schaffner, William, Van Beneden, Chris A.

“…Objectives Routine surveillance for streptococcal toxic shock syndrome (STSS), a severe manifestation of invasive group A Streptococcus (GAS) infections,…”
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Oxiconazole Potentiates Gentamicin against Gentamicin-Resistant Staphylococcus aureus In Vitro and In Vivo by Kaul, Grace, Akhir, Abdul, Shukla, Manjulika, Shafi, Hasham, Akunuri, Ravikumar, Pawar, Gaurav, Ghouse, Mahammad, Srinivas, Nanduri, Chopra, Sidharth

“…Amid the mounting burden of multidrug-resistant (MDR) bacterial infections on health care worldwide, drug repurposing, a time and cost-effective strategy to…”
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M1 UK lineage in invasive group A streptococcus isolates from the USA by Li, Yuan, Nanduri, Srinivas Acharya, Van Beneden, Chris A, Beall, Bernard W

“…Large-scale genomic examinations of this M1UK clade indicated a single lineage in the global group A streptococcus genomic databases, with only one isolate…”
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Effectiveness of the Pfizer-BioNTech COVID-19 Vaccine Among Residents of Two Skilled Nursing Facilities Experiencing COVID-19 Outbreaks - Connecticut, December 2020-February 2021 by Britton, Amadea, Jacobs Slifka, Kara M, Edens, Chris, Nanduri, Srinivas Acharya, Bart, Stephen M, Shang, Nong, Harizaj, Adora, Armstrong, Jillian, Xu, Kerui, Ehrlich, Hanna Y, Soda, Elizabeth, Derado, Gordana, Verani, Jennifer R, Schrag, Stephanie J, Jernigan, John A, Leung, Vivian H, Parikh, Sunil

“…Residents of long-term care facilities (LTCFs), particularly those in skilled nursing facilities (SNFs), have experienced disproportionately high levels of…”
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DRF 3188 a novel semi-synthetic analog of andrographolide: cellular response to MCF 7 breast cancer cells by Satyanarayana, Chitkala, Deevi, Dhanavanthri S, Rajagopalan, R, Srinivas, Nanduri, Rajagopal, Sriram

“…We determined the effect of andrographolide and one of its novel semi-synthetic analog, DRF 3188, on the cell cycle of MCF 7 breast cancer cells. The effect of…”
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Concurrent determination of ezetimibe and its phase-I and II metabolites by HPLC with UV detection: Quantitative application to various in vitro metabolic stability studies and for qualitative estimation in bile by Basha, Shaik Jafar Sadik, Naveed, Shaik Abdul, Tiwari, Nirbhay Kumar, Shashikumar, Dhanya, Muzeeb, Syed, Kumar, Thammera Ranjith, Kumar, Nyavanandi Vijay, Rao, Nadipalli Prabhakar, Srinivas, Nanduri, Mullangi, Ramesh, Srinivas, Nuggehally R.

“…Simultaneous separation and quantification of ezetimibe (EZM) and its phase-I metabolite i.e., ezetimibe ketone (EZM-K) and phase-II metabolite i.e., ezetimibe…”
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4(3H)-Quinazolinone derivatives: Promising antibacterial drug leads by Gatadi, Srikanth, Lakshmi, T. Vasanta, Nanduri, Srinivas

“…Emergence of drug resistance has created unmet medical need for the development of new classes of antibiotics. Discovery of new antibacterial agents with new…”
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Effectiveness of a COVID-19 Additional Primary or Booster Vaccine Dose in Preventing SARS-CoV-2 Infection Among Nursing Home Residents During Widespread Circulation of the Omicron Variant - United States, February 14-March 27, 2022 by Prasad, Namrata, Derado, Gordana, Nanduri, Srinivas Acharya, Reses, Hannah E, Dubendris, Heather, Wong, Emily, Soe, Minn Minn, Li, Qunna, Dollard, Philip, Bagchi, Suparna, Edwards, Jonathan, Shang, Nong, Budnitz, Dan, Bell, Jeneita, Verani, Jennifer R, Benin, Andrea, Link-Gelles, Ruth, Jernigan, John, Pilishvili, Tamara

“…Nursing home residents have experienced disproportionally high levels of COVID-19-associated morbidity and mortality and were prioritized for early COVID-19…”
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Rh(III)-Catalyzed Chemodivergent Annulations between Indoles and Iodonium Carbenes: A Rapid Access to Tricyclic and Tetracyclic N‑Heterocylces by Nunewar, Saiprasad, Kumar, Sanjeev, Pandhare, Harishchandra, Nanduri, Srinivas, Kanchupalli, Vinaykumar

“…Herein, we report an acid-controlled highly tunable selectivity of Rh­(III)-catalyzed [4 + 2] and [3 + 3] annulations of N-carboxamide indoles with iodonium…”
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