Search Results - "Nandula, Subhadra V"

Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: Potential role in progression by Scotto, Luigi, Narayan, Gopeshwar, Nandula, Subhadra V., Arias-Pulido, Hugo, Subramaniyam, Shivakumar, Schneider, Achim, Kaufmann, Andreas M., Wright, Jason D., Pothuri, Bhavana, Mansukhani, Mahesh, Murty, Vundavalli V.

“…Recurrent karyotypic abnormalities are a characteristic feature of cervical cancer (CC) cells, which may result in deregulated expression of important genes…”
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Cytogenetic analysis of 130 renal oncocytomas identify three distinct and mutually exclusive diagnostic classes of chromosome aberrations by Anderson, Christopher B., Lipsky, Michael, Nandula, Subhadra V., Freeman, Christopher E., Matthews, Thomas, Walsh, Caitlin E., Li, Gen, Szabolcs, Matthias, Mansukhani, Mahesh M., McKiernan, James M., Murty, Vundavalli V.

“…The cytogenetic alterations in renal oncocytoma (RO) are poorly understood. We analyzed 130 consecutive RO for karyotypic alterations. Clonal chromosome…”
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Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma by Pasqualucci, Laura, Compagno, Mara, Houldsworth, Jane, Monti, Stefano, Grunn, Adina, Nandula, Subhadra V, Aster, Jon C, Murty, Vundavally V, Shipp, Margaret A, Dalla-Favera, Riccardo

“…PR domain containing 1 with zinc finger domain (PRDM1)/B lymphocyte-induced maturation protein 1 (BLIMP1) is a transcriptional repressor expressed in a subset…”
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Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice by Cattoretti, Giorgio, Pasqualucci, Laura, Ballon, Gianna, Tam, Wayne, Nandula, Subhadra V., Shen, Qiong, Mo, Tongwei, Murty, Vundavalli V., Dalla-Favera, Riccardo

“…Diffuse large B cell lymphomas (DLBCL) derive from germinal center (GC) B cells and display chromosomal alterations deregulating the expression of BCL6, a…”
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Polysomy and p16 deletion by fluorescence in situ hybridization in the diagnosis of indeterminate biliary strictures by Gonda, Tamas A., MD, Glick, Michael P., MD, Sethi, Amrita, MD, Poneros, John M., MD, Palmas, Walter, MD, Iqbal, Shahzad, MD, Gonzalez, Susana, MD, Nandula, Subhadra V., MD, Emond, Jean C., MD, Brown, Robert S., MD, MPH, Murty, Vundavalli V., PhD, Stevens, Peter D., MD

“…Background The diagnosis of indeterminate biliary strictures is limited because of the low sensitivity of cytology. However, an accurate diagnosis of…”
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A Genomic Algorithm for the Molecular Classification of Common Renal Cortical Neoplasms: Development and Validation by Gowrishankar, Banumathy, Przybycin, Christopher G, Ma, Charles, Nandula, Subhadra V, Rini, Brian, Campbell, Steven, Klein, Eric, Chaganti, R.S.K, Magi-Galluzzi, Cristina, Houldsworth, Jane

“…Purpose Accurate discrimination of benign oncocytoma and malignant renal cell carcinoma is useful for planning appropriate treatment strategies for patients…”
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Gene dosage alterations revealed by cDNA microarray analysis in cervical cancer: Identification of candidate amplified and overexpressed genes by Narayan, Gopeshwar, Bourdon, Veronique, Chaganti, Seeta, Arias-Pulido, Hugo, Nandula, Subhadra V., Rao, Pulivarthi H., Gissmann, Lutz, Dürst, Matthias, Schneider, Achim, Pothuri, Bhavana, Mansukhani, Mahesh, Basso, Katia, Chaganti, R. S. K., Murty, Vundavalli V.

“…Cervical cancer (CC) cells exhibit complex karyotypic alterations, which is consistent with deregulation of numerous critical genes in its formation and…”
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Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha by Scotto, Luigi, Narayan, Gopeshwar, Nandula, Subhadra V, Subramaniyam, Shivakumar, Kaufmann, Andreas M, Wright, Jason D, Pothuri, Bhavana, Mansukhani, Mahesh, Schneider, Achim, Arias-Pulido, Hugo, Murty, Vundavalli V

“…Copy number gains and amplifications are characteristic feature of cervical cancer (CC) genomes for which the underlying mechanisms are unclear. These changes…”
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Promoter methylation-mediated inactivation of PCDH10 in acute lymphoblastic leukemia contributes to chemotherapy resistance by Narayan, Gopeshwar, Freddy, Allen J., Xie, Dongxu, Liyanage, Hema, Clark, Lorraine, Kisselev, Sergey, Un Kang, Ji, Nandula, Subhadra V., McGuinn, Catherine, Subramaniyam, Shivakumar, Alobeid, Bachir, Satwani, Prakash, Savage, David, Bhagat, Govind, Murty, Vundavalli V.

“…PCDH10 has been implicated as a tumor suppressor, since epigenetic alterations of this gene have been noted in multiple tumor types. However, to date, studies…”
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Mutations of multiple genes cause deregulation of NF- B in diffuse large B-cell lymphoma by Pasqualucci, Laura, Compagno, Mara, Lim, Wei Keat, Grunn, Adina, Nandula, Subhadra V, Brahmachary, Manisha, Shen, Qiong, Bertoni, Francesco, Ponzoni, Maurilio, Scandurra, Marta, Califano, Andrea, Bhagat, Govind, Chadburn, Amy, Dalla-Favera, Riccardo

“…Diffuse large B-cell lymphoma (DLBCL), the most common form of lymphoma in adulthood, comprises multiple biologically and clinically distinct subtypes…”
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Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma by Compagno, Mara, Lim, Wei Keat, Grunn, Adina, Nandula, Subhadra V., Brahmachary, Manisha, Shen, Qiong, Bertoni, Francesco, Ponzoni, Maurilio, Scandurra, Marta, Califano, Andrea, Bhagat, Govind, Chadburn, Amy, Dalla-Favera, Riccardo, Pasqualucci, Laura

“…A20 link to B-cell lymphoma Two groups report in this issue that A20 protein, a negative regulator of NF-κB signalling pathways, is frequently inactivated in…”
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Structural Requirements for the BARD1 Tumor Suppressor in Chromosomal Stability and Homology-directed DNA Repair by Laufer, Marsha, Nandula, Subhadra V., Modi, Ami P., Wang, Shuang, Jasin, Maria, Murty, Vundavalli V. V.S., Ludwig, Thomas, Baer, Richard

“…The BRCA1 tumor suppressor exists as a heterodimeric complex with BARD1, and this complex is thought to mediate many of the functions ascribed to BRCA1,…”
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Cytogenetic analysis of B-cell posttransplant lymphoproliferations validates the World Health Organization classification and suggests inclusion of florid follicular hyperplasia as a precursor lesion by Vakiani, Efsevia, MD, PhD, Nandula, Subhadra V., PhD, Subramaniyam, Shivakumar, PhD, Keller, Christian E., MD, Alobeid, Bachir, MD, Murty, Vundavalli V., PhD, Bhagat, Govind, MD

“…Summary Cytogenetic abnormalities in B-cell posttransplant lymphoproliferative disorders (PTLD) have not been well characterized. We thus performed cytogenetic…”
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Diffuse large B-cell lymphoma with TEL/ETV6 translocation by Sevilla, Deborah W., MD, Nandula, Subhadra V., PhD, Colovai, Adriana I., PhD, Alexander, Suzy, MS, Murty, Vundavalli V., PhD, Alobeid, Bachir, MD, Bhagat, Govind, MD

“…Summary Cytogenetic abnormalities of chromosome 12p involving the TEL/ETV6 gene are observed in a variety of hematopoietic neoplasms including acute leukemias,…”
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PCDH10 promoter hypermethylation is frequent in most histologic subtypes of mature lymphoid malignancies and occurs early in lymphomagenesis by Narayan, Gopeshwar, Xie, Dongxu, Freddy, Allen J., Ishdorj, Ganchimeg, Do, Catherine, Satwani, Prakash, Liyanage, Hema, Clark, Lorraine, Kisselev, Sergey, Nandula, Subhadra V., Scotto, Luigi, Alobeid, Bachir, Savage, David, Tycko, Benjamin, O'Connor, Owen A., Bhagat, Govind, Murty, Vundavalli V.

“…PCDH10 is epigenetically inactivated in multiple tumor types; however, studies in mature lymphoid malignancies are limited. Here, we have investigated the…”
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Promoter hypermethylation of FANCF: Disruption of Fanconi anemia-BRCA pathway in cervical cancer by NARAYAN, Gopeshwar, ARIAS-PULIDO, Hugo, GISSMANN, Lutz, DÜRST, Matthias, POTHURI, Bhavana, MURTY, Vundavalli V. V. S, NANDULA, Subhadra V, BASSO, Katia, SUGIRTHARAJ, Dorcas D, VARGAS, Hernan, MANSUKHANI, Mahesh, VILLELLA, Jeannine, MEYER, Larissa, SCHNEIDER, Achim

“…Patients with advanced stage invasive cervical cancer (CC) exhibit highly complex genomic alterations and respond poorly to conventional treatment protocols…”
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Cytogenetic abnormalities in reactive lymphoid hyperplasia: byproducts of the germinal centre reaction or indicators of lymphoma? by Sevilla, Deborah W., Murty, Vundavalli V., Sun, Xin-Lai, Nandula, Subhadra V., Mansukhani, Mahesh M., Alobeid, Bachir, Bhagat, Govind

“…Non‐random karyotypic abnormalities associated with non‐Hodgkin lymphomas (NHLs) have been described in cases of reactive lymphoid hyperplasia (RLH). However,…”
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KHSV− EBV− post‐transplant effusion lymphoma with plasmablastic features: variant of primary effusion lymphoma? by Lambe, Jennifer S., Oble, Darryl A., Nandula, Subhadra V., Sevilla, Deborah W., Colovai, Adriana I., Mansukhani, Mahesh, Chari, Ajai, Murty, Vundavalli V., Alobeid, Bachir, Bhagat, Govind

“…Primary effusion lymphoma (PEL) is a rare type of B‐cell non‐Hodgkin lymphoma (NHL), which predominantly occurs in HIV‐infected individuals, and is…”
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Congenital MLL-positive B-cell acute lymphoblastic leukemia (B-ALL) switched lineage at relapse to acute myelocytic leukemia (AML) with persistent t(4;11) and t(1;6) translocations and JH gene rearrangement by Jiang, Jie-Gen, Roman, Elizabeth, Nandula, Subhadra V, Murty, Vundavalli VS, Bhagat, Govind, Alobeid, Bachir

“…Congenital acute leukemia is a rare form of childhood leukemia, in which lineage conversion at relapse is very rarely reported. Here we describe a case of…”
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Two somatic biallelic lesions within and near SMAD4 in a human breast cancer cell line by Jakob, John, Nagase, Satoru, Gazdar, Adi, Chien, Minchen, Morozova, Irina, Russo, James J., Nandula, Subhadra V., Murty, Vundavalli V. V. S., Li, Chi-Ming, Tycko, Benjamin, Parsons, Ramon

“…Loss of chromosome arm 18q is a common event in human pancreatic, colon, and breast cancers and is often interpreted as representing loss of one or more…”
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