Search Results - "Nandini, Chilkunda D"
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Glycosaminoglycans from fresh water fish processing discard - Isolation, structural characterization, and osteogenic activity
Published in International journal of biological macromolecules (15-02-2020)“…Glycosaminoglycans (GAGs) play an important role in various biological activities. A lot of them are present in fish processing discards from abattoirs and…”
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AMPK differentially alters sulphated glycosaminoglycans under normal and high glucose milieu in proximal tubular cells
Published in Journal of biochemistry (Tokyo) (01-01-2021)“…Glycosaminoglycans (GAGs) and AMP-activated protein kinase (AMPK) are two critical molecular players involved in cellular homeostasis. Both of them are altered…”
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Effect of pathological conditions on peritoneal macrophage glycosaminoglycans: Impact on cytoadherence
Published in International journal of biological macromolecules (01-11-2016)“…Glycosaminoglycans (GAGs) have a plethora of functions to play. They are widely present in extracellular matrix, cell surface and inside the cell. During…”
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Glycosaminoglycan remodeling during diabetes and the role of dietary factors in their modulation
Published in World journal of diabetes (25-02-2016)“…Glycosaminoglycans(GAGs) play a significant role in various aspects of cell physiology.These are complex polymeric molecules characterized by disaccharides…”
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Structure of Pleiotrophin- and Hepatocyte Growth Factor-binding Sulfated Hexasaccharide Determined by Biochemical and Computational Approaches
Published in The Journal of biological chemistry (03-09-2010)“…Endogenous pleiotrophin and hepatocyte growth factor (HGF) mediate the neurite outgrowth-promoting activity of chondroitin sulfate (CS)/dermatan sulfate (DS)…”
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Hyperphagia in offsprings of in utero hyperglycemic mothers is associated with increased expression of heparan sulfate proteoglycans in hypothalamus
Published in Molecular and cellular biochemistry (01-08-2022)“…In utero hyperglycemia has consequences on future outcomes in the offsprings. We had earlier shown that in utero hyperglycemia impacts…”
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Morus alba Leaf Bioactives Modulate Peroxisome Proliferator Activated Receptor γ in the Kidney of Diabetic Rat and Impart Beneficial Effect
Published in Journal of agricultural and food chemistry (01-08-2018)“…Peroxisome proliferator activated receptor gamma (PPARγ) is a ligand-activated nuclear receptor that can be activated or repressed by several exogenous and…”
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High cholesterol-supplemented diet during gestation and lactation alters liver glycosaminoglycans and associated lipoprotein receptors and results in fat accumulation in adulthood
Published in Nutrition research (New York, N.Y.) (01-09-2021)“…In utero insults to growing fetus impact its health in adulthood. Glycosaminoglycans (GAGs) are involved in lipoprotein metabolism in the liver and vary both…”
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Zerumbone Ameliorates High Glucose-Induced Reduction in AMP-Activated Protein Kinase Phosphorylation in Tubular Kidney Cells
Published in Journal of agricultural and food chemistry (25-10-2017)“…AMP-activated protein kinase (AMPK) plays an important role in pathophysiology of diabetes and its complications. In recent years, its role in kidney as a…”
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Banana (Musa sp. var. elakki bale) Flower and Pseudostem: Dietary Fiber and Associated Antioxidant Capacity
Published in Journal of agricultural and food chemistry (11-01-2012)“…Banana flower (BF) and pseudostem (PS) are byproducts of banana cultivation and are known to have health beneficial effects. The main objective of this study…”
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One-pot analysis of sulfated glycosaminoglycans
Published in Glycoconjugate journal (01-02-2018)“…Routine isolation, estimation, and characterization of glycosaminoglycans (GAGs) is quite challenging. This is compounded by the fact that the analysis is…”
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Tinospora cordifolia consumption ameliorates changes in kidney chondroitin sulphate/dermatan sulphate in diabetic rats
Published in Journal of nutritional science (Cambridge) (2012)“…Diabetes is known to alter kidney extracellular matrix (ECM) components. Chondroitin sulphate (CS)/dermatan sulphate (DS), an ECM component, which plays an…”
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Glypican-1 Is Frequently Overexpressed in Human Gliomas and Enhances FGF-2 Signaling in Glioma Cells
Published in The American journal of pathology (01-06-2006)“…Signaling by fibroblast growth factor 2 (FGF-2), an autocrine stimulator of glioma growth, is regulated by heparan sulfate proteoglycans (HSPGs) via a ternary…”
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Structural Features of Arabinoxylans from Bajra (Pearl Millet)
Published in Journal of agricultural and food chemistry (23-10-2002)“…Structures of arabinoxylans (AX) from bajra, from a variety known to have characteristic quality in the making of roti, an unleavened flat bread, were…”
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Glucose uptake-stimulatory activity of Tinospora cordifolia stem extracts in Ehrlich ascites tumor cell model system
Published in Journal of food science and technology (01-01-2014)“…Diabetes mellitus is a multifunctional disorder with several causes and multiple consequences. Nutraceuticals play a vital role in ameliorating diabetic…”
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Stimulation of glucose uptake by Musa sp. (cv. elakki bale) flower and pseudostem extracts in Ehrlich ascites tumor cells
Published in Journal of the science of food and agriculture (01-06-2011)“…BACKGROUND: Glucose uptake study plays a major role in diabetes research. Impaired glucose uptake has been implicated in the development of hyperglycemia…”
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Novel 70-kDa Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains with a Unique Heterogenous Sulfation Pattern from Shark Skin, Which Exhibit Neuritogenic Activity and Binding Activities for Growth Factors and Neurotrophic Factors
Published in The Journal of biological chemistry (11-02-2005)“…Chondroitin sulfate (CS) and dermatan sulfate (DS) hybrid chains of proteoglycans are critical in growth factor binding, neuritogenesis, and brain development…”
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