Search Results - "Nandi, Somen"

The Emergency Response Capacity of Plant-Based Biopharmaceutical Manufacturing-What It Is and What It Could Be by Tusé, Daniel, Nandi, Somen, McDonald, Karen A., Buyel, Johannes Felix

“…Several epidemic and pandemic diseases have emerged over the last 20 years with increasing reach and severity. The current COVID-19 pandemic has affected most…”
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Development and simulation of fully glycosylated molecular models of ACE2-Fc fusion proteins and their interaction with the SARS-CoV-2 spike protein binding domain by Bernardi, Austen, Huang, Yihan, Harris, Bradley, Xiong, Yongao, Nandi, Somen, McDonald, Karen A, Faller, Roland

“…We develop fully glycosylated computational models of ACE2-Fc fusion proteins which are promising targets for a COVID-19 therapeutic. These models are tested…”
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Techno-economic analysis of a transient plant-based platform for monoclonal antibody production by Nandi, Somen, Kwong, Aaron T, Holtz, Barry R, Erwin, Robert L, Marcel, Sylvain, McDonald, Karen A

“…Plant-based biomanufacturing of therapeutic proteins is a relatively new platform with a small number of commercial-scale facilities, but offers advantages of…”
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Analysis of Variability of Functionals of Recombinant Protein Production Trajectories Based on Limited Data by Liao, Shuting, Macharoen, Kantharakorn, McDonald, Karen A., Nandi, Somen, Paul, Debashis

“…Making statistical inference on quantities defining various characteristics of a temporally measured biochemical process and analyzing its variability across…”
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When Super-Resolution Localization Microscopy Meets Carbon Nanotubes by Nandi, Somen, Caicedo, Karen, Cognet, Laurent

“…We recently assisted in a revolution in the realm of fluorescence microscopy triggered by the advent of super-resolution techniques that surpass the classic…”
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Structural relaxation of acridine orange dimer in bulk water and inside a single live lung cell by Chowdhury, Rajdeep, Nandi, Somen, Halder, Ritaban, Jana, Biman, Bhattacharyya, Kankan

“…Structural relaxation of the acridine orange (AO) dimer in bulk water and inside a single live lung cell is studied using time resolved confocal microscopy and…”
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Spectral mapping of 3D multi-cellular tumor spheroids: time-resolved confocal microscopy by Mohapatra, Saswat, Nandi, Somen, Chowdhury, Rajdeep, Das, Gaurav, Ghosh, Surajit, Bhattacharyya, Kankan

“…A tumor-like multi-cellular spheroid (3D) differs from a 2D cell in a number of ways. This is demonstrated using time resolved confocal microscopy. Two…”
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Interaction of proteins with ionic liquid, alcohol and DMSO and in situ generation of gold nano-clusters in a cell by Nandi, Somen, Parui, Sridip, Halder, Ritaban, Jana, Biman, Bhattacharyya, Kankan

“…In this review, we give a brief overview on how the interaction of proteins with ionic liquids, alcohols and dimethyl sulfoxide (DMSO) influences the…”
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In Vivo Glycan Engineering via the Mannosidase I Inhibitor (Kifunensine) Improves Efficacy of Rituximab Manufactured in Nicotiana benthamiana Plants by Kommineni, Vally, Markert, Matthew, Ren, Zhongjie, Palle, Sreenath, Carrillo, Berenice, Deng, Jasmine, Tejeda, Armando, Nandi, Somen, McDonald, Karen A, Marcel, Sylvain, Holtz, Barry

“…N-glycosylation has been shown to affect the pharmacokinetic properties of several classes of biologics, including monoclonal antibodies, blood factors, and…”
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Evaluating the Cost of Pharmaceutical Purification for a Long-Duration Space Exploration Medical Foundry by McNulty, Matthew J., Berliner, Aaron J., Negulescu, Patrick G., McKee, Liber, Hart, Olivia, Yates, Kevin, Arkin, Adam P., Nandi, Somen, McDonald, Karen A.

“…There are medical treatment vulnerabilities in longer-duration space missions present in the current International Space Station crew health care system with…”
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Effects of N-Glycosylation on the Structure, Function, and Stability of a Plant-Made Fc-Fusion Anthrax Decoy Protein by Xiong, Yongao, Karuppanan, Kalimuthu, Bernardi, Austen, Li, Qiongyu, Kommineni, Vally, Dandekar, Abhaya M, Lebrilla, Carlito B, Faller, Roland, McDonald, Karen A, Nandi, Somen

“…Protein N-glycosylation is an important post-translational modification and has influences on a variety of biological processes at the cellular and molecular…”
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Transient Recombinant Protein Production in Glycoengineered Nicotiana benthamiana Cell Suspension Culture by Sukenik, Sara C, Karuppanan, Kalimuthu, Li, Qiongyu, Lebrilla, Carlito B, Nandi, Somen, McDonald, Karen A

“…Transient recombinant protein production is a promising alternative to stable transgenic systems, particularly for emergency situations in which rapid…”
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Effects of Kifunensine on Production and N -Glycosylation Modification of Butyrylcholinesterase in a Transgenic Rice Cell Culture Bioreactor by Macharoen, Kantharakorn, Li, Qiongyu, Márquez-Escobar, Veronica A, Corbin, Jasmine M, Lebrilla, Carlito B, Nandi, Somen, McDonald, Karen A

“…The production and -glycosylation of recombinant human butyrylcholinesterase (BChE), a model highly glycosylated therapeutic protein, in a transgenic rice cell…”
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Resource interaction in smallholder farms is linked to farm sustainability: evidence from Indian Sundarbans by Goswami, Rupak, Brodt, Sonja, Patra, Sangita, Dasgupta, Purnabha, Mukherjee, Biswanath, Nandi, Somen

“…Efficient resource utilization in small-scale farms is crucial to achieving farm sustainability through endogenous mechanisms. However, the precise mechanisms…”
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Probing Deviation of Adhered Membrane Dynamics between Reconstituted Liposome and Cellular System by Mondal, Prasenjit, Chowdhury, Rajdeep, Nandi, Somen, Amin, Md. Asif, Bhattacharyya, Kankan, Ghosh, Surajit

“…The dynamics of cell‐cell adhesion are complicated due to complexities in cellular interactions and intra‐membrane interactions. In the present work, we have…”
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Physical chemistry in a single live cell: confocal microscopy by Amin, Md Asif, Nandi, Somen, Mondal, Prasenjit, Mahata, Tanushree, Ghosh, Surajit, Bhattacharyya, Kankan

“…A live cell is a complex, yet extremely important container. Understanding the dynamics in a selected intracellular component is a challenging task. We have…”
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A one health framework to advance food safety and security: An on-farm case study in the Rwandan dairy sector by Garcia, Sara N., Mpatswenumugabo, Jean Pierre M., Ntampaka, Pie, Nandi, Somen, Cullor, James S.

“…In Rwanda, cattle and milk hold a cultural and historical significance, providing an opportunity for pro-dairy governmental policies aimed to alleviate food…”
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Process Simulation and Techno-Economic Analysis of Large-Scale Bioproduction of Sweet Protein Thaumatin II by Kelada, Kirolos D, Tusé, Daniel, Gleba, Yuri, McDonald, Karen A, Nandi, Somen

“…There are currently worldwide efforts to reduce sugar intake due to the various adverse health effects linked with the overconsumption of sugars. Artificial…”
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Functionalizing silica sol-gel with entrapped plant virus-based immunosorbent nanoparticles by McNulty, Matthew J, Hamada, Naomi, Delzio, Jesse, McKee, Liber, Nandi, Somen, Longo, Marjorie L, McDonald, Karen A

“…Advancements in understanding and engineering of virus-based nanomaterials (VBNs) for biomedical applications motivate a need to explore the interfaces between…”
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Towards a Biomanufactory on Mars by Berliner, Aaron J., Hilzinger, Jacob M., Abel, Anthony J., McNulty, Matthew J., Makrygiorgos, George, Averesch, Nils J. H., Sen Gupta, Soumyajit, Benvenuti, Alexander, Caddell, Daniel F., Cestellos-Blanco, Stefano, Doloman, Anna, Friedline, Skyler, Ho, Davian, Gu, Wenyu, Hill, Avery, Kusuma, Paul, Lipsky, Isaac, Mirkovic, Mia, Luis Meraz, Jorge, Pane, Vincent, Sander, Kyle B., Shi, Fengzhe, Skerker, Jeffrey M., Styer, Alexander, Valgardson, Kyle, Wetmore, Kelly, Woo, Sung-Geun, Xiong, Yongao, Yates, Kevin, Zhang, Cindy, Zhen, Shuyang, Bugbee, Bruce, Clark, Douglas S., Coleman-Derr, Devin, Mesbah, Ali, Nandi, Somen, Waymouth, Robert M., Yang, Peidong, Criddle, Craig S., McDonald, Karen A., Seefeldt, Lance C., Menezes, Amor A., Arkin, Adam P.

“…A crewed mission to and from Mars may include an exciting array of enabling biotechnologies that leverage inherent mass, power, and volume advantages over…”
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