Search Results - "Nandakumar, Krishna S."

A novel herbal formulation "LiverCare" differentially regulates primary rat hepatocyte and hepatocarcinoma cell proliferation in vitro by Vidyashankar, Satyakumar, Varma, Sandeep R, Azeemudin, Mohammed, Godavarthi, Ashok, Krishna, Nandakumar S, Patki, Pralhad Sadashiv

“…Hepatocyte growth factor (HGF) plays an important role in hepatocyte proliferation. HGF expression is regulated by various signaling molecules and nuclear…”
Get more information

Alcohol depletes coenzyme-Q(10) associated with increased TNF-alpha secretion to induce cytotoxicity in HepG2 cells by Vidyashankar, Satyakumar, Nandakumar, Krishna S, Patki, Pralhad S

“…Alcohol consumption has been implicated to cause severe hepatic steatosis which is mediated by alcohol dehydrogenase (ADH) activity and CYP(450) 2E1…”
Get full text

Alcohol depletes coenzyme-Q10 associated with increased TNF-alpha secretion to induce cytotoxicity in HepG2 cells by Vidyashankar, Satyakumar, Nandakumar, Krishna S, Patki, Pralhad S

“…Highlights ► Ethanol induced cytotoxicity in HepG2 cells in absence of lipogenesis. ► Ethanol inhibited HMG-CoA reductase activity. ► Ethanol induced HMG-CoA…”
Get full text

Liv.52 protects HepG2 cells from oxidative damage induced by tert-butyl hydroperoxide by Vidyashankar, S, Mitra, S.K, Nandakumar, Krishna S

“…Oxidative stress induced by toxicants is known to cause various complications in the liver. Herbal drug such as Liv.52 is found to have hepatoprotective…”
Get full text

Liv.52 regulates ethanol induced PPARγ and TNF α expression in HepG2 cells by Mitra, Shankar K, Varma, Sandeep Ravi, Godavarthi, Ashok, Nandakumar, Krishna S

“…Liver is a prime target of alcohol-induced damage by inducing inflammatory cytokines especially tumor necrosis factor alpha (TNFα). Activator of peroxisome…”
Get full text

Liv.52 up-regulates cellular antioxidants and increase glucose uptake to circumvent oleic acid induced hepatic steatosis in HepG2 cells by Vidyashankar, Satyakumar, Sharath Kumar, L.M., Barooah, Vandana, Sandeep Varma, R., Nandakumar, Krishna S., Patki, Pralhad Sadashiv

“…HepG2 cells were rendered steatotic by supplementing 2.0mM oleic acid (OA) in the culture media for 24h. OA induced hepatic steatosis in HepG2 cells was marked…”
Get full text

Ethanol extract of Justicia gendarussa inhibits lipopolysaccharide stimulated nitric oxide and matrix metalloproteinase-9 expression in murine macrophage by Varma, R Sandeep, Ashok, G, Vidyashankar, S, Patki, P, Nandakumar, Krishna S

“…Justicia gendarussa Burm (Acanthaceae) is a plant used to treat inflammatory diseases such as rheumatoid arthritis. However, the mechanism involved in the…”
Get more information

Water-soluble compounds in the herbal preparation Abana inhibit lipid biosynthesis and enhance cholesterol efflux in HepG2 cells by Vidyashankar, Satyakumar, Godavarthi, Ashok, Varma, R Sandeep, Nandakumar, Krishna S

“…Higher concentrations of circulating lipids (cholesterol and triglycerides) and their decreased catabolism pose a major risk in the development of…”
Get more information

Liv.52 regulates ethanol induced PPARgamma and TNF alpha expression in HepG2 cells by Mitra, Shankar K, Varma, Sandeep Ravi, Godavarthi, Ashok, Nandakumar, Krishna S

“…Liver is a prime target of alcohol-induced damage by inducing inflammatory cytokines especially tumor necrosis factor alpha (TNFalpha). Activator of peroxisome…”
Get full text

Liv.52 regulates ethanol induced PPAR[gamma] and TNF [alpha] expression in HepG2 cells by Mitra, Shankar K, Varma, Sandeep Ravi, Godavarthi, Ashok, Nandakumar, Krishna S

“…Liver is a prime target of alcohol-induced damage by inducing inflammatory cytokines especially tumor necrosis factor alpha (TNFα). Activator of peroxisome…”
Get full text

Evaluation of in vitro toxicity of Rumalaya liniment using mouse embryonic fibroblasts and human keratinocytes by Varma, SandeepRavi, Godavarthi, Ashok, Vidyashankar, Satyakumar, Nandakumar, KrishnaS, Patki, PralhadSadashiv

“…The skin irritation potential of topical formulations is investigated prior to human exposure to identify the chemicals which might induce adverse skin…”
Get full text