Search Results - "Nan, Kaihui"
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Implantation of biomimetic polydopamine nanocomposite scaffold promotes optic nerve regeneration through modulating inhibitory microenvironment
Published in Journal of nanobiotechnology (07-11-2024)“…Abstract Optic nerve regeneration remains challenging worldwide due to the limited intrinsic regenerative capacity of retinal ganglion cells (RGCs) and the…”
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In vivo evaluation of curcumin nanoformulation loaded methoxy poly(ethylene glycol)-graft-chitosan composite film for wound healing application
Published in Carbohydrate polymers (17-03-2012)“…► A novel curcumin nanoformulation was developed absence of any stabilizer and surfactant. ► Curcumin nanoformulation loaded MPEG-CS composite film was…”
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Efficiency against multidrug resistance by co-delivery of doxorubicin and curcumin with a legumain-sensitive nanocarrier
Published in Nano research (01-07-2018)“…Multidrug resistance proteins (MDRPs), which are implicated in the mediation of multidrug resistance in tumors, represent the main obstacle to successful…”
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Fabrication of chitosan based nanocomposite with legumain sensitive properties using charge driven self-assembly strategy
Published in Journal of materials science. Materials in medicine (01-09-2018)“…Chitosan (CS) based nanoparticles (NPs) have several advantages in delivering drugs. They are usually prepared in a micro-emulsion solvent system but this…”
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Efficiency Encapsulation of FK506 with New Dual Self‐Assembly Multi‐Hydrophobic‐Core Nanoparticles for Preventing Keratoplasty Rejection
Published in Advanced healthcare materials (01-08-2023)“…Nanoparticles self‐assembled by amphiphilic copolymers for loading hydrophobic molecules are intensively investigated. However, their hydrophobic…”
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An adherent drug depot for retinal ganglion cell protection and regeneration in rat traumatic optic neuropathy models
Published in RSC advances (28-06-2021)“…Traumatic optic neuropathy (TON) describes an injury to the optic nerve following either blunt or penetrating trauma, and remains an important cause of vision…”
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Curcumin micelles suppress gastric tumor cell growth by upregulating ROS generation, disrupting redox equilibrium and affecting mitochondrial bioenergetics
Published in Food & function (01-05-2020)“…Gastric cancer is the fourth most common cancer and the second most frequent cause of cancer death worldwide. Chemotherapy is an important treatment. However,…”
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Localized co-delivery of CNTF and FK506 using a thermosensitive hydrogel for retina ganglion cells protection after traumatic optic nerve injury
Published in Drug delivery (01-01-2020)“…Following the traumatic axonal injury in the optic nerve, the failure of retrograde axonal transport to continuously supply neurotrophins from the brain to…”
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Fabrication of nonfouling, bactericidal, and bacteria corpse release multifunctional surface through surface-initiated RAFT polymerization
Published in International journal of nanomedicine (01-01-2017)“…Infections after surgery or endophthalmitis are potentially blinding complications caused by bacterial adhesion and subsequent biofilm formation on the…”
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Remote-controlled dexamethasone-duration on eye-surface with a micelle-magnetic nanoparticulate co-delivery system for dry eye disease
Published in Acta pharmaceutica Sinica. B (01-08-2024)“…Dexamethasone (DEX) is used to treat ocular surface diseases. However, regulating DEX duration in tears while preventing its absorption into the anterior…”
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Co-delivery strategies based on multifunctional nanocarriers for cancer therapy
Published in Current drug metabolism (01-10-2012)“…Chemotherapy is among the most common means for clinicians in the fight against various types of tumors. However, severe toxicity with undesirable toxic…”
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Self-Healing Alginate Hydrogel Formed by Dynamic Benzoxaborolate Chemistry Protects Retinal Pigment Epithelium Cells against Oxidative Damage
Published in Gels (29-12-2022)“…Oxidative stress is considered as a major factor causing retinal pigment epithelium (RPE) dysfunction and finally leading to retinal diseases such as…”
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Characterization and biocompatibility of nanohybrid scaffold prepared via in situ crystallization of hydroxyapatite in chitosan matrix
Published in Colloids and surfaces, B, Biointerfaces (01-12-2010)“…Hydroxyapatite (HAP) precursor solution was first mixed with an acetic acid chitosan (CS) solution. The mixture was then lyophilized to form the original…”
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Biomechanical Considerations of Patching Material for Posterior Scleral Reinforcement Surgery
Published in Frontiers in medicine (16-05-2022)“…To characterize biomechanical properties of genipin-crosslinked human dura mater as reinforcing material for posterior scleral reinforcement (PSR) and to…”
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Electrospun fibrous scaffold of hydroxyapatite/poly (ε-caprolactone) for bone regeneration
Published in Journal of materials science. Materials in medicine (01-02-2012)“…Development of fibrous scaffold of hydroxyapatite/biopolymer nanocomposite offers great potential in the field of bone regeneration and tissue engineering…”
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A combined chitosan/nano-size hydroxyapatite system for the controlled release of icariin
Published in Journal of materials science. Materials in medicine (01-02-2012)“…Icariin, a plant-derived flavonol glycoside, has been proved as an osteoinductive agent for bone regeneration. For this reason, we developed an icariin-loaded…”
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Characterisation of systemic and ocular drug level of triamcinolone acetonide following a single sub-Tenon injection
Published in British journal of ophthalmology (01-05-2010)“…AIM To characterise the pharmacokinetics of triamcinolone acetonide (TA) in various ocular tissues following a single sub-Tenon injection. METHODS Twenty-one…”
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Hydroxyapatite coatings produced on commercially pure titanium by micro-arc oxidation
Published in Biomedical materials (Bristol) (01-09-2007)“…A porous hydroxyapatite (HA) coating on commercially pure titanium was prepared by micro-arc oxidation (MAO) in electrolytic solution containing calcium…”
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Ectopic osteogenic ability of calcium phosphate scaffolds cultured with osteoblasts
Published in Journal of biomedical materials research. Part A (01-05-2010)“…Bone substitute materials can induce bone formation when combined with mesenchymal stem cells (MSC). The aim of the current study was to examine in vivo…”
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