Search Results - "Nampoothiri, Sreekala S"
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ISCHEMIRs: Finding a Way Through the Obstructed Cerebral Arteries
Published in Current drug targets (01-06-2016)“…MicroRNAs (miRNAs) are small (19-25 nucleotides) non-coding single-stranded RNAs that control post-transcriptional gene expression. miRNAs are abundantly…”
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Role of KCa3.1 Channels in CNS Diseases: A Concise Review
Published in CNS & neurological disorders drug targets (01-01-2016)“…KCa3.1 protein is part of a heterotetrameric voltage-independent potassium channel, the activity of which depends on the intracellular calcium binding to…”
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miR-9 Upregulation Integrates Post-ischemic Neuronal Survival and Regeneration In Vitro
Published in Cellular and molecular neurobiology (01-03-2019)“…The irrefutable change in the expression of brain-enriched microRNAs (miRNAs) following ischemic stroke has promoted the development of radical miRNA-based…”
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Folic Acid Exerts Post-Ischemic Neuroprotection In Vitro Through HIF-1α Stabilization
Published in Molecular neurobiology (01-11-2018)“…The constant failure of single-target drug therapies for ischemic stroke necessitates the development of novel pleiotropic pharmacological treatment…”
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Decoding the ubiquitous role of microRNAs in neurogenesis
Published in Molecular neurobiology (01-04-2017)“…Neurogenesis generates fledgling neurons that mature to form an intricate neuronal circuitry. The delusion on adult neurogenesis was far resolved in the past…”
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Rodent Gymnastics: Neurobehavioral Assays in Ischemic Stroke
Published in Molecular neurobiology (01-11-2017)“…Despite years of research, most preclinical trials on ischemic stroke have remained unsuccessful owing to poor methodological and statistical standards leading…”
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A Novel Five-Node Feed-Forward Loop Unravels miRNA-Gene-TF Regulatory Relationships in Ischemic Stroke
Published in Molecular neurobiology (01-11-2018)“…The complex and interlinked cascade of events regulated by microRNAs (miRNAs), transcription factors (TF), and target genes highlight the multifactorial nature…”
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