Search Results - "Nami, Fatemeharefeh"

Strategies for In Vivo Genome Editing in Nondividing Cells by Nami, Fatemeharefeh, Basiri, Mohsen, Satarian, Leila, Curtiss, Cameron, Baharvand, Hossein, Verfaillie, Catherine

“…Programmable nucleases, including zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced…”
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Human stem cell–derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2 by Claes, Christel, Van Den Daele, Johanna, Boon, Ruben, Schouteden, Sarah, Colombo, Alessio, Monasor, Laura Sebastian, Fiers, Mark, Ordovás, Laura, Nami, FatemehArefeh, Bohrmann, Bernd, Tahirovic, Sabina, De Strooper, Bart, Verfaillie, Catherine M.

“…Murine microglia expressing the Alzheimer's disease–linked TREM2R47H mutation display variable decrease in phagocytosis, while impaired phagocytosis is…”
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Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response by Germeys, Christine, Vandoorne, Tijs, Davie, Kristofer, Poovathingal, Suresh, Heeren, Kara, Vermeire, Wendy, Nami, FatemehArefeh, Moisse, Matthieu, Quaegebeur, Annelies, Sierksma, Annerieke, Rué, Laura, Sicart, Adrià, Eykens, Caroline, De Cock, Lenja, De Strooper, Bart, Carmeliet, Peter, Van Damme, Philip, De Bock, Katrien, Van Den Bosch, Ludo

“…Neuroinflammation and dysregulated energy metabolism are linked to motor neuron degeneration in amyotrophic lateral sclerosis (ALS). The egl-9 family…”
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HiPSC-Derived Hepatocyte-like Cells Can Be Used as a Model for Transcriptomics-Based Study of Chemical Toxicity by Ghosh, Sreya, De Smedt, Jonathan, Tricot, Tine, Proença, Susana, Kumar, Manoj, Nami, Fatemeharefeh, Vanwelden, Thomas, Vidal, Niels, Jennings, Paul, Kramer, Nynke I, Verfaillie, Catherine M

“…Traditional toxicity risk assessment approaches have until recently focussed mainly on histochemical readouts for cell death. Modern toxicology methods attempt…”
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Therapeutic modalities and novel approaches in regenerative medicine for COVID-19 by Ramezankhani, Roya, Solhi, Roya, Memarnejadian, Arash, Nami, Fatemeharefeh, Hashemian, Seyed Mohammad Reza, Tricot, Tine, Vosough, Massoud, Verfaillie, Catherine

“…•Direct cytopathic effect and immunopathological pathogenesis are two of the main underlying mechanisms for severe pulmonary injury in patients with…”
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Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs by Zhu, Yingli, Burg, Thibaut, Neyrinck, Katrien, Vervliet, Tim, Nami, Fatemeharefeh, Vervoort, Ellen, Ahuja, Karan, Sassano, Maria Livia, Chai, Yoke Chin, Tharkeshwar, Arun Kumar, De Smedt, Jonathan, Hu, Haibo, Bultynck, Geert, Agostinis, Patrizia, Swinnen, Johannes V., Van Den Bosch, Ludo, da Costa, Rodrigo Furtado Madeiro, Verfaillie, Catherine

“…Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and fatal neurodegenerative disorder, characterized by selective loss of motor neurons (MNs). A…”
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Correction to: Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs by Zhu, Yingli, Burg, Thibaut, Neyrinck, Katrien, Vervliet, Tim, Nami, Fatemeharefeh, Vervoort, Ellen, Ahuja, Karan, Sassano, Maria Livia, Chai, Yoke Chin, Tharkeshwar, Arun Kumar, De Smedt, Jonathan, Hu, Haibo, Bultynck, Geert, Agostinis, Patrizia, Swinnen, Johannes V., Van Den Bosch, Ludo, da Costa, Rodrigo Furtado Madeiro, Verfaillie, Catherine

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Generation of a human induced pluripotent stem cell–based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration by García-León, Juan Antonio, Cabrera-Socorro, Alfredo, Eggermont, Kristel, Swijsen, Ann, Terryn, Joke, Fazal, Raheem, Nami, FatemehArefeh, Ordovás, Laura, Quiles, Ana, Lluis, Frederic, Serneels, Lutgarde, Wierda, Keimpe, Sierksma, Annerieke, Kreir, Mohamed, Pestana, Francisco, Van Damme, Philip, De Strooper, Bart, Thorrez, Lieven, Ebneth, Andreas, Verfaillie, Catherine M.

“…Tauopathies are neurodegenerative diseases characterized by TAU protein–related pathology, including frontotemporal dementia and Alzheimer's disease among…”
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Fast and Efficient Generation of Isogenic Induced Pluripotent Stem Cell Lines Using Adenine Base Editing by Nami, Fatemeharefeh, Ramezankhani, Roya, Vandenabeele, Marjan, Vervliet, Tim, Vogels, Kristy, Urano, Fumihiko, Verfaillie, Catherine

“…Isogenic induced pluripotent stem cell (iPSC) lines are currently mostly created by homology directed repair evoked by a double-strand break (DSB) generated by…”
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