Search Results - "Nam Hyung Kim"

Generation of homogeneous midbrain organoids with in vivo‐like cellular composition facilitates neurotoxin‐based Parkinson's disease modeling by Kwak, Tae Hwan, Kang, Ji Hyun, Hali, Sai, Kim, Jonghun, Kim, Kee‐Pyo, Park, Chanhyeok, Lee, Ju‐Hyun, Ryu, Ha Kyun, Na, Ji Eun, Jo, Junghyun, Je, Hyunsoo Shawn, Ng, Huck‐Hui, Kwon, Jeongwoo, Kim, Nam‐Hyung, Hong, Kwon Ho, Sun, Woong, Chung, Chi Hye, Rhyu, Im Joo, Han, Dong Wook

“…Recent studies have demonstrated the generation of midbrain‐like organoids (MOs) from human pluripotent stem cells. However, the low efficiency of MO…”
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Meiotic spindle formation in mammalian oocytes: implications for human infertility by Namgoong, Suk, Kim, Nam-Hyung

“…In the final stage of oogenesis, mammalian oocytes generate a meiotic spindle and undergo chromosome segregation to yield an egg that is ready for…”
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Functional roles of hnRNPA2/B1 regulated by METTL3 in mammalian embryonic development by Kwon, Jeongwoo, Jo, Yu-Jin, Namgoong, Suk, Kim, Nam-Hyung

“…Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2/B1) plays an important role in RNA processing via in m 6 A modification of pre-mRNA or pre-miRNA…”
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Arp2/3 complex regulates asymmetric division and cytokinesis in mouse oocytes by Sun, Shao-Chen, Wang, Zhen-Bo, Xu, Yong-Nan, Lee, Seung-Eun, Cui, Xiang-Shun, Kim, Nam-Hyung

“…Mammalian oocyte meiotic maturation involves oocyte polarization and a unique asymmetric division, but until now, the underlying mechanisms have been poorly…”
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Melatonin enhances the developmental competence of porcine somatic cell nuclear transfer embryos by preventing DNA damage induced by oxidative stress by Liang, Shuang, Jin, Yong-Xun, Yuan, Bao, Zhang, Jia-Bao, Kim, Nam-Hyung

“…Melatonin has antioxidant and scavenger effects in the cellular antioxidant system. This research investigated the protective effects and underlying mechanisms…”
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Melatonin protects oocytes from MEHP exposure-induced meiosis defects in porcine by Zhang, Yu, Wang, Teng, Lan, Mei, Zang, Xin-Wei, Li, Yi-Lun, Cui, Xiang-Shun, Kim, Nam-Hyung, Sun, Shao-Chen

“…In 2011, DEHP (plasticizer) was reported to illegally be added in food and beverage products in Taiwan, which caused great concerns about food safety…”
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TP53BP1 regulates chromosome alignment and spindle bipolarity in mouse oocytes by Jin, Zhe‐Long, Suk, Namgoong, Kim, Nam‐Hyung

“…Meiotic oocytes lack classic centrosomes; therefore, bipolar spindle assembly depends on the clustering of acentriolar microtubule‐organizing centers (MTOCs)…”
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Mycotoxin-containing diet causes oxidative stress in the mouse by Hou, Yan-Jun, Zhao, Yong-Yan, Xiong, Bo, Cui, Xiang-Shun, Kim, Nam-Hyung, Xu, Yin-Xue, Sun, Shao-Chen

“…Mycotoxins which mainly consist of Aflatoxin (AF), Zearalenone (ZEN) and Deoxynivalenol (DON) are commonly found in many food commodities. Although each…”
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Quercetin delays postovulatory aging of mouse oocytes by regulating SIRT expression and MPF activity by Wang, HaiYang, Jo, Yu-Jin, Oh, Jeong Su, Kim, Nam-Hyung

“…If no fertilization occurs at an appropriate time after ovulation, oocyte quality deteriorates rapidly as a process called postovulatory aging. Because the…”
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Melatonin alleviates defects induced by zearalenone during porcine embryo development by Yao, Xuerui, Jiang, Hao, Gao, Qingshan, Li, Ying-Hua, Xu, Yong Nan, Kim, Nam-Hyung

“…Zearalenone (ZEA), which is produced by several fusarium mycotoxins, is found in animal feed and food products, and can exert estrogen-like activity. Melatonin…”
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The possible molecular mechanisms of bisphenol A action on porcine early embryonic development by Guo, Jing, Zhao, Ming-Hui, Shin, Kyung-Tae, Niu, Ying-Jie, Ahn, Yong-Dae, Kim, Nam-Hyung, Cui, Xiang-Shun

“…Bisphenol A (BPA) is an environmental contaminant widely used in the plastic industry. BPA has been demonstrated to be an endocrine disruptor and has an…”
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Toxic effects of atrazine on porcine oocytes and possible mechanisms of action by Yuan, Bao, Liang, Shuang, Jin, Yong-Xun, Zhang, Ming-Jun, Zhang, Jia-Bao, Kim, Nam-Hyung

“…Because atrazine is a widely used herbicide, its adverse effects on the reproductive system have been extensively researched. In this study, we investigated…”
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KRAS Affects Adipogenic Differentiation by Regulating Autophagy and MAPK Activation in 3T3-L1 and C2C12 Cells by Yu, Wenjie, Chen, Cheng-Zhen, Peng, Yanxia, Li, Ze, Gao, Yan, Liang, Shuang, Yuan, Bao, Kim, Nam-Hyung, Jiang, Hao, Zhang, Jia-Bao

“…Kirsten rat sarcoma 2 viral oncogene homolog ( ) is a proto-oncogene that encodes the small GTPase transductor protein KRAS, which has previously been found to…”
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Autophagy is required for proper meiosis of porcine oocytes maturing in vitro by Shen, Xing-Hui, Jin, Yong-Xun, Liang, Shuang, Kwon, Jeong-Woo, Zhu, Ji-Wei, Lei, Lei, Kim, Nam-Hyung

“…Autophagy is an essential cellular mechanism that degrades cytoplasmic proteins and organelles to recycle their components; however, the contribution of…”
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Inhibition of Fatty Acid Synthase Reduces Blastocyst Hatching through Regulation of the AKT Pathway in Pigs by Guo, Jing, Kim, Nam-Hyung, Cui, Xiang-Shun

“…Fatty acid synthase (FASN) is an enzyme responsible for the de novo synthesis of long-chain fatty acids. During oncogenesis, FASN plays a role in growth and…”
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Filamin A is required for spindle migration and asymmetric division in mouse oocytes by Wang, HaiYang, Guo, Jing, Lin, ZiLi, Namgoong, Suk, Oh, Jeong Su, Kim, Nam‐Hyung

“…ABSTRACT Dynamic changes in the actin network are crucial for the cortical migration of spindles and establishment of polarity, to ensure asymmetric division…”
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Insulin interacts with PPARγ agonists to promote bovine adipocyte differentiation by Guo, Pan−Pan, Yao, Xue−Rui, Xu, Yong−Nan, Jin, Xin, Li, Qiang, Yan, Chang−Guo, Kim, Nam−Hyung, Li, Xiang−Zi

“…Insulin is a potent adipogenic hormone that triggers a series of transcription factors that regulate the differentiation of preadipocytes into mature…”
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Generation of transgenic chickens expressing the human erythropoietin (hEPO) gene in an oviduct-specific manner: Production of transgenic chicken eggs containing human erythropoietin in egg whites by Kwon, Mo Sun, Koo, Bon Chul, Kim, Dohyang, Nam, Yu Hwa, Cui, Xiang-Shun, Kim, Nam-Hyung, Kim, Teoan

“…The transgenic chicken has been considered as a prospective bioreactor for large-scale production of costly pharmaceutical proteins. In the present study, we…”
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Dihydromyricetin supplementation during in vitro culture improves porcine oocyte developmental competence by regulating oxidative stress by WANG, Jing, JIN, Qing-Guo, LIU, Rong-Ping, WANG, Xin-Qin, LI, Ying-Hua, KIM, Nam-Hyung, XU, Yong-Nan

“…Dihydromyricetin (DHM), a dihydroflavonoid compound, exhibits a variety of biological activities, including antitumor activity. However, the effects of DHM on…”
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CRISPR/Cas9 as tool for functional study of genes involved in preimplantation embryo development by Kwon, Jeongwoo, Namgoong, Suk, Kim, Nam-Hyung

“…The CRISPR/Cas9 system has proven to be an efficient gene-editing tool for genome modification of cells and organisms. However, the applicability and…”
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