Search Results - "Nam, Yunchan"

A Platform for the Synthesis of Corynantheine-Type Corynanthe Alkaloids by Nam, Yunchan, Tam, Anthony T., Miller, Eric R., Scheidt, Karl A.

“…Corynantheine-type alkaloids are major components of the Mitragyna speciosa, also known as kratom, that exhibit unique pharmacological activity. However, no…”
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Structural Modification and Characteristics of Lappaconitine Alkaloid for the Discovery of Bioactive Components by Hypervalent Iodine Reagent by Moon, Chang Sang, Kang, Heung Mo, Nam, Yunchan, Lim, Jiwoong, Kim, Jiewan, Lee, Tae-Hee, Lee, Junho, Chang, Mun Seog, Lee, Jae Yeol

“…Lappaconitine, a diterpene alkaloid isolated from Aconitum sinomontanum Nakai, exhibits a wide range of biological activities, making it a promising candidate…”
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Discovery of N-amido-phenylsulfonamide derivatives as novel microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors by Kim, Misong, Kim, Geuntae, Kang, Minji, Ko, Dohyeong, Nam, Yunchan, Moon, Chang Sang, Kang, Heung Mo, Shin, Ji-Sun, Werz, Oliver, Lee, Kyung-Tae, Lee, Jae Yeol

“…[Display omitted] Our previous research showed that N-carboxy-phenylsulfonyl hydrazide (scaffold A) could reduce LPS-stimulated PGE2 levels in RAW 264.7…”
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Synthesis and cytotoxic effects of 2-thio-3,4-dihydroquinazoline derivatives as novel T-type calcium channel blockers by Nam, Yunchan, Ryu, Ki Deok, Jang, Changyoung, Moon, Yoon Hyoung, Kim, Misong, Ko, Dohyeong, Chung, Kyung-Sook, Gandini, Maria A., Lee, Kyung-Tae, Zamponi, Gerald W., Lee, Jae Yeol

“…[Display omitted] In our previous work, a series of 2-amino-3,4-dihydroquinazoline derivativesusing an electron acceptor group was reported to be potent T-type…”
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Inhibition of LPS-Induced PGE2 Production by Arylsulfonamide Derivatives via the Selective Inhibition of mPGES-1 Enzyme by Misong Kim, Changyoung Jang, Yunchan Nam, Kyung-Tae Lee, Jaeyeol Lee

“…Microsomal prostaglandin E synthase-1 (mPGES-1) is responsible for the massive prostaglandin E2 (PGE2) formation during inflammation. Increasing evidence…”
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Discovery of N-amido-phenylsulfonamide derivatives as novel microsomal prostaglandin E 2 synthase-1 (mPGES-1) inhibitors by Kim, Misong, Kim, Geuntae, Kang, Minji, Ko, Dohyeong, Nam, Yunchan, Moon, Chang Sang, Kang, Heung Mo, Shin, Ji-Sun, Werz, Oliver, Lee, Kyung-Tae, Lee, Jae Yeol

“…Our previous research showed that N-carboxy-phenylsulfonyl hydrazide (scaffold A) could reduce LPS-stimulated PGE levels in RAW 264.7 macrophage cells by an…”
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