Search Results - "Nam, Kyung‐Soo"

Combined doxorubicin and arctigenin treatment induce cell cycle arrest‐associated cell death by promoting doxorubicin uptake in doxorubicin‐resistant breast cancer cells by Lee, Min‐Gu, Lee, Kyu‐Shik, Nam, Kyung‐Soo

“…Chemotherapy failure is often caused by drug resistance, for which no effective treatment strategy has been established. Many studies have been undertaken with…”
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Arctigenin attenuates platelet activation and clot retraction by regulation of thromboxane A2 synthesis and cAMP pathway by Nam, Gi Suk, Nam, Kyung-Soo

“…[Display omitted] •Arctigenin inhibited platelet aggregation stimulated by collagen, thrombin, and ADP without cytotoxicity.•Arctigenin attenuated clot…”
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Inhibition of TPA‑induced metastatic potential by morin hydrate in MCF‑7 human breast cancer cells via the Akt/GSK‑3β/c‑Fos signaling pathway by Lee, Kyu‑Shik, Nam, Gi Suk, Baek, Junyoung, Kim, Soyoung, Nam, Kyung‑Soo

“…Plant flavonoid 2′,3,4′,5,7-pentahydroxyflavone (morin hydrate), isolated from the family Moraceae (Morus alba L.), is known to have anti-inflammatory and…”
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Effect of proton-beam irradiation on cell survival of MCF-7 and its chemo-resistant subgroups by Maharjan, Sushma, Lee, Min-Gu, Nam, Kyung-Soo, Lee, Kyu-Shik

“…Proton beam (PB) therapy is gaining popularity for breast cancer treatment because of its enhanced coverage and potential to minimize late toxicities. The dose…”
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Daidzein Inhibits Human Platelet Activation by Downregulating Thromboxane A2 Production and Granule Release, Regardless of COX-1 Activity by Hong, Hyun-Jin, Nam, Gi-Suk, Nam, Kyung-Soo

“…Platelets play crucial roles in cardiovascular diseases (CVDs) by regulating hemostasis and blood coagulation at sites of blood vessel damage. Accumulating…”
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Arctigenin Enhances the Cytotoxic Effect of Doxorubicin in MDA-MB-231 Breast Cancer Cells by Lee, Kyu-Shik, Lee, Min-Gu, Kwon, Yun-Suk, Nam, Kyung-Soo

“…Several reports have described the anti-cancer activity of arctigenin, a lignan extracted from L. Here, we investigated the effect of arctigenin (ATG) on…”
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Overcoming radioresistance of breast cancer cells with MAP4K4 inhibitors by Kwon, Yun-Suk, Lee, Min-Gu, Kim, Nam-Yi, Nam, Gi Suk, Nam, Kyung-Soo, Jang, Hyunsoo, Kim, Soyoung

“…Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) has recently emerged as a promising therapeutic target in cancer. In this study, we explored…”
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The association of changes in RAD51 and survivin expression levels with the proton beam sensitivity of Capan‑1 and Panc‑1 human pancreatic cancer cells by Lee, Min-Gu, Lee, Kyu-Shik, Nam, Kyung-Soo

“…Fewer than 20% of patients diagnosed with pancreatic cancer can be treated with surgical resection. The effects of proton beam irradiation were evaluated on…”
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Refined Deep-Sea Water Suppresses Inflammatory Responses via the MAPK/AP-1 and NF-κB Signaling Pathway in LPS-Treated RAW 264.7 Macrophage Cells by Chun, So-Young, Lee, Kyu-Shik, Nam, Kyung-Soo

“…Atopic dermatitis (AD) is a type of inflammatory skin disease caused by genetics, immune system dysfunction, and environmental stresses. It is, however, still…”
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Anthocyanin Oligomers Induce Apoptosis and Autophagy by Inhibiting the mTOR Signaling Pathway in Human Breast Cancer Cells by Lee, Min-Gu, Hong, Hyun-Jin, Nam, Kyung-Soo

“…Anthocyanin oligomers (AOs) are phytochemicals synthesized by fermenting anthocyanins extracted from grape skins and are more biologically active than…”
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Morin Sensitizes MDA-MB-231 Triple-Negative Breast Cancer Cells to Doxorubicin Cytotoxicity by Suppressing FOXM1 and Attenuating EGFR/STAT3 Signaling Pathways by Maharjan, Sushma, Lee, Min-Gu, Kim, So-Young, Lee, Kyu-Shik, Nam, Kyung-Soo

“…Considerable emphasis is being placed on combinatorial chemotherapeutic/natural treatments for breast cancer. This study reveals the synergistic anti-tumor…”
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Anti‑platelet activity of mineral‑balanced deep sea water is mediated via the regulation of Akt and ERK pathway crosstalk by Nam, Gi Suk, Lee, Kyu-Shik, Nam, Kyung-Soo

“…Mineral-balanced deep sea water (MBDSW), an unlimited natural sea source, has been demonstrated to minimize the risk of developing cardiovascular diseases,…”
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The preventive effect of deep sea water on the development of cancerous skin cells through the induction of autophagic cell death in UVB-damaged HaCaT keratinocyte by Lee, Kyu-Shik, Lee, Min-Gu, Woo, Yun-Jeong, Nam, Kyung-Soo

“…Ultraviolet light (UV) is a major inducer of skin cancer. Therefore, recovery and removal of UV-damaged skin cells are important in the prevention of skin…”
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Proton Beam Induces P53-mediated Cell Cycle Arrest in HepG2 Hepatocellular Carcinoma Cells by Chun, So-Young, Nam, Kyung-Soo, Lee, Kyu-Shik

“…A proton beam (PB) can be used to treat various cancers. In the present study, we evaluated the effect of PB on HepG2 hepatocellular carcinoma cells. The…”
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Anti‑metastatic effects of arctigenin are regulated by MAPK/AP‑1 signaling in 4T‑1 mouse breast cancer cells by Lee, Min-Gu, Lee, Kyu-Shik, Nam, Kyung-Soo

“…Arctigenin is a natural lignan that is found in burdock with anti‑viral, ‑oxidative, ‑inflammatory and anti‑tumor activities. In the current study, the effect…”
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Deep sea water improves hypercholesterolemia and hepatic lipid accumulation through the regulation of hepatic lipid metabolic gene expression by Lee, Kyu-Shik, Chun, So-Young, Kwon, Yun-Suk, Kim, Soyoung, Nam, Kyung-Soo

“…A high-fat diet or high-cholesterol diet (HCD) is a major cause of metabolic diseases, including obesity and diabetes; vascular diseases, including…”
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Clinical significance of overexpression of NRG1 and its receptors, HER3 and HER4, in gastric cancer patients by Yun, Sumi, Koh, Jiwon, Nam, Soo Kyung, Park, Jung Ok, Lee, Sung Mi, Lee, Kyoungyul, Lee, Kyu Sang, Ahn, Sang-Hoon, Park, Do Joong, Kim, Hyung-Ho, Choe, Gheeyoung, Kim, Woo Ho, Lee, Hye Seung

“…Background Neuregulin 1 (NRG1), a ligand for human epidermal growth factor (HER) 3 and HER4, can activates cell signaling pathways to promote carcinogenesis…”
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Caffeic Acid Diminishes the Production and Release of Thrombogenic Molecules in Human Platelets by Nam, Gi Suk, Nam, Kyung-Soo, Park, Hwa-Jin

“…Caffeic acid (CA) is a well-known to inhibit thrombogenic thromboxane A 2 (TXA 2 ) production, but there are no reports for the supply and usage of its…”
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Metformin selectively targets 4T1 tumorspheres and enhances the antitumor effects of doxorubicin by downregulating the AKT and STAT3 signaling pathways by Kwon, Yun-Suk, Chun, So-Young, Nan, Hong-Yan, Nam, Kyung-Soo, Lee, Chuhee, Kim, Soyoung

“…Recent studies have reported that metformin (Met), the first-line medication for the treatment of type 2 diabetes, exhibited anticancer and chemoprotective…”
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Regulatory mechanism of mineral-balanced deep sea water on hypocholesterolemic effects in HepG2 hepatic cells by Lee, Kyu-Shik, Kwon, Yun-Suk, Kim, Soyoung, Moon, Deok-Soo, Kim, Hyeon Ju, Nam, Kyung-Soo

“…Abstract Several previous studies have shown the benefits of deep sea water (DSW) in lipid metabolism. However, the effects of DSW on cellular cholesterol…”
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