Search Results - "Nam, Ha"

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure by Qian, Xuyu, Nguyen, Ha Nam, Song, Mingxi M., Hadiono, Christopher, Ogden, Sarah C., Hammack, Christy, Yao, Bing, Hamersky, Gregory R., Jacob, Fadi, Zhong, Chun, Yoon, Ki-jun, Jeang, William, Lin, Li, Li, Yujing, Thakor, Jai, Berg, Daniel A., Zhang, Ce, Kang, Eunchai, Chickering, Michael, Nauen, David, Ho, Cheng-Ying, Wen, Zhexing, Christian, Kimberly M., Shi, Pei-Yong, Maher, Brady J., Wu, Hao, Jin, Peng, Tang, Hengli, Song, Hongjun, Ming, Guo-li

“…Cerebral organoids, three-dimensional cultures that model organogenesis, provide a new platform to investigate human brain development. High cost, variability,…”
Get full text

Using brain organoids to understand Zika virus-induced microcephaly by Qian, Xuyu, Nguyen, Ha Nam, Jacob, Fadi, Song, Hongjun, Ming, Guo-Li

“…Technologies to differentiate human pluripotent stem cells into three-dimensional organized structures that resemble organs are pushing the frontiers of human…”
Get full text

LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress by Nguyen, Ha Nam, Byers, Blake, Cord, Branden, Shcheglovitov, Aleksandr, Byrne, James, Gujar, Prachi, Kee, Kehkooi, Schüle, Birgitt, Dolmetsch, Ricardo E., Langston, William, Palmer, Theo D., Pera, Renee Reijo

“…Studies of Parkinson's disease (PD) have been hindered by lack of access to affected human dopaminergic (DA) neurons. Here, we report generation of induced…”
Get full text

Generation of human brain region–specific organoids using a miniaturized spinning bioreactor by Qian, Xuyu, Jacob, Fadi, Song, Mingxi Max, Nguyen, Ha Nam, Song, Hongjun, Ming, Guo-li

“…This protocol describes procedures for building the SpinΩ bioreactor for 3D tissue culture and differentiating human iPSCs into different brain region–specific…”
Get full text

Evaluation of methods to detect circular RNAs from single-end RNA-sequencing data by Nguyen, Manh Hung, Nguyen, Ha-Nam, Vu, Trung Nghia

“…Circular RNA (circRNA), a class of RNA molecule with a loop structure, has recently attracted researchers due to its diverse biological functions and potential…”
Get full text

Cell-level somatic mutation detection from single-cell RNA sequencing by Vu, Trung Nghia, Nguyen, Ha-Nam, Calza, Stefano, Kalari, Krishna R, Wang, Liewei, Pawitan, Yudi

“…Abstract Motivation Both single-cell RNA sequencing (scRNA-seq) and DNA sequencing (scDNA-seq) have been applied for cell-level genomic profiling. For mutation…”
Get full text

Epigallocatechin Gallate Inhibits the Uridylate-Specific Endoribonuclease Nsp15 and Efficiently Neutralizes the SARS-CoV‑2 Strain by Hong, Seokho, Seo, Sang Hwan, Woo, Sun-Je, Kwon, Yonghoon, Song, Manki, Ha, Nam-Chul

“…SARS-CoV-2, the coronavirus strain that initiated the COVID-19 pandemic, and its subsequent variants present challenges to vaccine development and treatment…”
Get full text

CircNetVis: an interactive web application for visualizing interaction networks of circular RNAs by Nguyen, Thi-Hau, Nguyen, Ha-Nam, Vu, Trung Nghia

“…Analyzing the interactions of circular RNAs (circRNAs) is a crucial step in understanding their functional impacts. While there are numerous visualization…”
Get full text

Structural and Biochemical Analysis of Butanol Dehydrogenase From Thermotoga maritima by Bai, Xue, Xu, Ke, Zhao, Zhidan, Qin, Huiwen, Nam, Ki Hyun, Quan, Chunshan, Ha, Nam‐Chul, Xu, Yongbin

“…ABSTRACT Butanol dehydrogenase (BDH) plays a crucial role in butanol biosynthesis by catalyzing the conversion of butanal to butanol using the coenzyme…”
Get full text

Isocitrate binds to the itaconic acid–responsive LysR-type transcriptional regulator RipR in Salmonella pathogenesis by Ki, Nayeon, Kim, Jinshil, Jo, Inseong, Hyun, Yongseong, Ryu, Sangryeol, Ha, Nam-Chul

“…Macrophages produce itaconic acid in phagosomes in response to bacterial cell wall component lipopolysaccharide to eliminate invading pathogenic bacteria…”
Get full text

LysPBC2, a Novel Endolysin Harboring a Bacillus cereus Spore Binding Domain by Kong, Minsuk, Na, Hongjun, Ha, Nam-Chul, Ryu, Sangryeol

“…To control the spore-forming human pathogen , we isolated and characterized a novel endolysin, LysPBC2, from a newly isolated phage, PBC2. Compared to the…”
Get full text

Vehicle Mode and Driving Activity Detection Based on Analyzing Sensor Data of Smartphones by Lu, Dang-Nhac, Nguyen, Duc-Nhan, Nguyen, Thi-Hau, Nguyen, Ha-Nam

“…In this paper, we present a flexible combined system, namely the Vehicle mode-driving Activity Detection System (VADS), that is capable of detecting either the…”
Get full text

Structural basis for lamin assembly at the molecular level by Ahn, Jinsook, Jo, Inseong, Kang, So-mi, Hong, Seokho, Kim, Suhyeon, Jeong, Soyeon, Kim, Yong-Hak, Park, Bum-Joon, Ha, Nam-Chul

“…Nuclear structure and function are governed by lamins, which are intermediate filaments that mostly consist of α-helices. Different lamin assembly models have…”
Get full text

Inland harmful cyanobacterial bloom prediction in the eutrophic Tri An Reservoir using satellite band ratio and machine learning approaches by Nguyen, Hao-Quang, Ha, Nam-Thang, Pham, Thanh-Luu

“…In recent years, Tri An, a drinking water reservoir for millions of people in southern Vietnam, has been affected by harmful cyanobacterial blooms (HCBs),…”
Get full text

The Impact of Perceived Brand Globalness on Consumers' Purchase Intention and the Moderating Role of Consumer Ethnocentrism: An Evidence from Vietnam by Vuong, Bui Nhat, Khanh Giao, Ha Nam

“…The aim of this research is to examine the effect of perceived brand globalness on consumers' purchase intention, noting the mediating roles of perceived brand…”
Get full text

Circall: fast and accurate methodology for discovery of circular RNAs from paired-end RNA-sequencing data by Nguyen, Dat Thanh, Trac, Quang Thinh, Nguyen, Thi-Hau, Nguyen, Ha-Nam, Ohad, Nir, Pawitan, Yudi, Vu, Trung Nghia

“…Circular RNA (circRNA) is an emerging class of RNA molecules attracting researchers due to its potential for serving as markers for diagnosis, prognosis, or…”
Get full text

KDM2B is a histone H3K79 demethylase and induces transcriptional repression via sirtuin‐1‐mediated chromatin silencing by Kang, Joo‐Young, Kim, Ji‐Young, Kim, Kee‐Beom, Park, Jin Woo, Cho, Hana, Hahm, Ja Young, Chae, Yun‐Cheol, Kim, Daehwan, Kook, Hyun, Rhee, Sangmyeong, Ha, Nam‐Chul, Seo, Sang‐Beom

“…ABSTRACT The methylation of histone H3 lysine 79 (H3K79) is an active chromatin marker and is prominent in actively transcribed regions of the genome; however,…”
Get full text

Analytical and Experimental Investigations of Omnidirectional Wireless Power Transfer Using a Cubic Transmitter by Ha-Van, Nam, Seo, Chulhun

“…In recent years, wireless power technology has been promoted for recharging systems for portable devices that are used in everyday life. The conventional…”
Get full text

Evaluating the predictive power of different machine learning algorithms for groundwater salinity prediction of multi-layer coastal aquifers in the Mekong Delta, Vietnam by Tran, Dang An, Tsujimura, Maki, Ha, Nam Thang, Nguyen, Van Tam, Binh, Doan Van, Dang, Thanh Duc, Doan, Quang-Van, Bui, Dieu Tien, Anh Ngoc, Trieu, Phu, Le Vo, Thuc, Pham Thi Bich, Pham, Tien Dat

“…[Display omitted] •Top ten influencing factors of groundwater salinization were identified.•The CatBoost Regression model provides the highest accuracy…”
Get full text

Modeling a Genetic Risk for Schizophrenia in iPSCs and Mice Reveals Neural Stem Cell Deficits Associated with Adherens Junctions and Polarity by Yoon, Ki-Jun, Nguyen, Ha Nam, Ursini, Gianluca, Zhang, Fengyu, Kim, Nam-Shik, Wen, Zhexing, Makri, Georgia, Nauen, David, Shin, Joo Heon, Park, Youngbin, Chung, Raeeun, Pekle, Eva, Zhang, Ce, Towe, Maxwell, Hussaini, Syed Mohammed Qasim, Lee, Yohan, Rujescu, Dan, St. Clair, David, Kleinman, Joel E., Hyde, Thomas M., Krauss, Gregory, Christian, Kimberly M., Rapoport, Judith L., Weinberger, Daniel R., Song, Hongjun, Ming, Guo-li

“…Defects in brain development are believed to contribute toward the onset of neuropsychiatric disorders, but identifying specific underlying mechanisms has…”
Get full text