Synthesis, Characterization, Anticancer, and Antimicrobial Activities of Bimetallic Silver and Gold Nanoparticles Synthesized Using a Purple Non‐Sulfur Bacterium Rhodopseudomonas faecalis

Synthesis, Characterization, Anticancer, and Antimicrobial Activities of Bimetallic Silver and Gold Nanoparticles Synthesized Using a Purple Non‐Sulfur Bacterium Rhodopseudomonas faecalis

One of the recent and actively researched areas is the synthesis of bimetallic nanoparticles (BMNPs). Silver and gold BMNPs are prepared from aqueous AgNO3 and HAuCL4 as the precursors using the as prepared culture filtrate of Rhodopseudomonas faecalis as a reducing agent in aqueous medium. An ambie...

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Bibliographic Details
Published in:Macromolecular symposia. Vol. 407; no. 1
Main Authors: Nalvolthula, Raju, Merugu, Ramchander, Koyyati, Rama, Rudra, M. P. Pratap
Format: Journal Article
Language:English
Published: Weinheim Wiley Subscription Services, Inc 01-02-2023
Subjects:
Ambient temperature
antibacterial activity
anticancer activity
Anticancer properties
Antiinfectives and antibacterials
Antimicrobial agents
Antitumor activity
Antitumor agents
Aqueous solutions
bimetallic nanoparticles
Bimetals
Cancer
Cell culture
Cytotoxicity
Gold
Nanoparticles
Reducing agents
Rhodopseudomonas
Rhodopseudomonas faecalis
Scanning electron microscopy
Silver
Silver nitrate
Synthesis
Toxicity
Tumor cell lines
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Summary:One of the recent and actively researched areas is the synthesis of bimetallic nanoparticles (BMNPs). Silver and gold BMNPs are prepared from aqueous AgNO3 and HAuCL4 as the precursors using the as prepared culture filtrate of Rhodopseudomonas faecalis as a reducing agent in aqueous medium. An ambient temperature of 25°C is maintained throughout the process, where the AgNO3 and HAuCL4 solution in 1:1 v/v is stirred continuously and culture filtrate is added. The synthesis of gold and silver nanoparticles is shown by the brown color which indicates the formation of composite nanoparticles. The characterization is done using different kinds of techniques. Synthesized nanoparticles size is in the range between 31.71 and 153.7 nm. Scanning electron microscopy (SEM) analysis shows that the nanoparticles are in small and round in shape. The anticancer and antimicrobial activities of the BMNPs are investigated. Anticancer activity of composite nanoparticles reveals that the composite nanoparticles show more cytotoxicity toward cancer cell lines HT‐29 and MCF‐7. The synthesized composite nanoparticles can be used as efficient antimicrobials and anticancer agents for diagnosis, treatment of various infections, and cancers.
ISSN:1022-1360
1521-3900
DOI:10.1002/masy.202100373