Search Results - "Naluyima, Prossy"

Evidence of Orientia spp. Endemicity among Severe Infectious Disease Cohorts, Uganda by Blair, Paul W, Kobba, Kenneth, Okello, Stephen, Alharthi, Sultanah, Naluyima, Prossy, Clemens, Emily, Kibuuka, Hannah, Clark, Danielle V, Kakooza, Francis, Lamorde, Mohammed, Manabe, Yukari C, Dumler, J Stephen, Illness, Acute Febrile

“…At 3 severe infection cohort sites in Uganda, Orientia seropositivity was common. We identified 4 seroconversion cases and 1 PCR-positive case. These results…”
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High frequency of HIV precursor-target-specific B cells in sub-Saharan populations by Matassoli, Flavio, Cagigi, Alberto, Shen, Chen-Hsiang, Henry, Amy R., Johnston, Timothy S., Schramm, Chaim A., Cottrell, Christopher A., Kalyuzhniy, Oleksandr, Spangler, Abby, Ndung'u, Thumbi, Dong, Krista, Eller, Leigh, Robb, Merlin, Eller, Michael, Naluyima, Prossy, Kwong, Peter D., Douek, Daniel C., Schief, William R., Andrews, Sarah F., McDermott, Adrian B.

“…HIV gp120 engineered outer domain germline-targeting version 8 (eOD-GT8) was designed specifically to engage naive B cell precursors of VRC01-class antibodies…”
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The Joint Mobile Emerging Disease Clinical Capability (JMEDICC) laboratory approach: Capabilities for high-consequence pathogen clinical research by Naluyima, Prossy, Kayondo, Willy, Ritchie, Chi, Wandege, Joseph, Kagabane, Sharon, Tumubeere, Lydia, Kusiima, Brenda, Kibombo, Daniel, Atukunda, Sharon, Nanteza, Christine, Nabirye, Harriet, Mugabi, Francis Bunjo, Namuyanja, Sarah, Hatcher, Christopher, Rauch, Hypaitia, Mukembo, Moses, Musinguzi, Patrick, Sanders, Nathan, Turesson, Elizabeth, Cando, Christian, Walwema, Richard, Mimbe, Derrick, Hepburn, Janice, Clark, Danielle, Lamorde, Mohammed, Kibuuka, Hannah, Zaman, Saima, Cardile, Anthony P, Martins, Karen A

“…Following the 2013-2016 Ebola virus outbreak in West Africa, numerous groups advocated for the importance of executing clinical trials in outbreak settings…”
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Sex and Urbanicity Contribute to Variation in Lymphocyte Distribution across Ugandan Populations by Naluyima, Prossy, Eller, Leigh Anne, Ouma, Benson J, Kyabaggu, Denis, Kataaha, Peter, Guwatudde, David, Kibuuka, Hannah, Wabwire-Mangen, Fred, Robb, Merlin L, Michael, Nelson L, de Souza, Mark S, Sandberg, Johan K, Eller, Michael A

“…Management of patient care and interpretation of research data require evaluation of laboratory results in the context of reference data from populations with…”
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In-vitro Immunomodulatory activity of Azadirachta indica A.Juss. Ethanol: water mixture against HIV associated chronic CD4 + T-cell activation/ exhaustion by Olwenyi, Omalla A, Asingura, Bannet, Naluyima, Prossy, Anywar, Godwin Upoki, Nalunga, Justine, Nakabuye, Mariam, Semwogerere, Michael, Bagaya, Bernard, Cham, Fatim, Tindikahwa, Allan, Kiweewa, Francis, Lichter, Eliezer Z, Podany, Anthony T, Fletcher, Courtney V, Byrareddy, Siddappa N, Kibuuka, Hannah

“…In Sub-Saharan Africa, herbal therapy continues to be utilized for HIV-1 disease management. However, the therapeutic benefits of these substances remain…”
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Innate and adaptive immune responses both contribute to pathological CD4 T cell activation in HIV-1 infected Ugandans by Eller, Michael A, Blom, Kim G, Gonzalez, Veronica D, Eller, Leigh Anne, Naluyima, Prossy, Laeyendecker, Oliver, Quinn, Thomas C, Kiwanuka, Noah, Serwadda, David, Sewankambo, Nelson K, Tasseneetrithep, Boonrat, Wawer, Maria J, Gray, Ronald H, Marovich, Mary A, Michael, Nelson L, de Souza, Mark S, Wabwire-Mangen, Fred, Robb, Merlin L, Currier, Jeffrey R, Sandberg, Johan K

“…HIV-1 disease progression is associated with persistent immune activation. However, the nature of this association is incompletely understood. Here, we…”
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Quality Monitoring of HIV-1-Infected and Uninfected Peripheral Blood Mononuclear Cell Samples in a Resource-Limited Setting by Olemukan, Robert E, Eller, Leigh Anne, Ouma, Benson J, Etonu, Ben, Erima, Simon, Naluyima, Prossy, Kyabaggu, Denis, Cox, Josephine H, Sandberg, Johan K, Wabwire-Mangen, Fred, Michael, Nelson L, Robb, Merlin L, de Souza, Mark S, Eller, Michael A

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Safety and Immunogenicity of Accelerated Heterologous 2-Dose Ebola Vaccine Regimens in Adults With and Without HIV in Africa by Mwesigwa, Betty, Sawe, Fredrick, Oyieko, Janet, Mwakisisile, Joel, Viegas, Edna, Akintunde, Gideon Akindiran, Kosgei, Josphat, Kokogho, Afoke, Ntinginya, Nyanda, Jani, Ilesh, Shukarev, Georgi, Hooper, Jay W, Kwilas, Steven A, Ward, Lucy A, Rusnak, Janice, Bounds, Callie, Overman, Rachel, Badorrek, Christopher S, Eller, Leigh Anne, Eller, Michael A, Polyak, Christina S, Moodley, Amber, Tran, Chi L, Costanzo, Margaret C, Leggat, David J, Paquin-Proulx, Dominic, Naluyima, Prossy, Anumendem, Dickson Nkafu, Gaddah, Auguste, Luhn, Kerstin, Hendriks, Jenny, McLean, Chelsea, Douoguih, Macaya, Kibuuka, Hannah, Robb, Merlin L, Robinson, Cynthia, Ake, Julie A

“…Shorter prophylactic vaccine schedules may offer more rapid protection against Ebola in resource-limited settings. This randomized, observer-blind,…”
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Safety, tolerability, and immunogenicity of the Ebola Sudan chimpanzee adenovirus vector vaccine (cAd3-EBO S) in healthy Ugandan adults: a phase 1, open-label, dose-escalation clinical trial by Mwesigwa, Betty, Houser, Katherine V, Hofstetter, Amelia R, Ortega-Villa, Ana M, Naluyima, Prossy, Kiweewa, Francis, Nakabuye, Immaculate, Yamshchikov, Galina V, Andrews, Charla, O'Callahan, Mark, Strom, Larisa, Schech, Steven, Anne Eller, Leigh, Sondergaard, Erica L, Scott, Paul T, Amare, Mihret F, Modjarrad, Kayvon, Wamala, Amir, Tindikahwa, Allan, Musingye, Ezra, Nanyondo, Jauhara, Gaudinski, Martin R, Gordon, Ingelise J, Holman, LaSonji A, Saunders, Jamie G, Costner, Pamela J M, Mendoza, Floreliz H, Happe, Myra, Morgan, Patricia, Plummer, Sarah H, Hickman, Somia P, Vazquez, Sandra, Murray, Tamar, Cordon, Jamilet, Dulan, Caitlyn N M, Hunegnaw, Ruth, Basappa, Manjula, Padilla, Marcelino, Gajjala, Suprabhath R, Swanson, 2nd, Phillip A, Lin, Bob C, Coates, Emily E, Gall, Jason G, McDermott, Adrian B, Koup, Richard A, Mascola, John R, Ploquin, Aurélie, Sullivan, Nancy J, Kibuuka, Hannah, Ake, Julie A, Ledgerwood, Julie E

“…Sudan Ebola virus can cause severe viral disease, with an average case fatality rate of 54%. A recent outbreak of Sudan Ebola virus in Uganda caused 55 deaths…”
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Sudan Virus Disease among Health Care Workers, Uganda, 2022 by Wailagala, Abdullah, Blair, Paul W., Kobba, Kenneth, Mubaraka, Kayiira, Aanyu-Tumukahebwa, Hellen, Kiiza, Daniel, Sekikongo, Musoke T., Klena, John D., Waitt, Peter, Bahatungire, Rony R., Kyobe, Henry S., Atwine, Diana, Adaku, Alex, Bongomin, Bodo, Kirenga, Bruce, Boore, Amy, Clark, Danielle V., Kaggwa, David, Gregory, Melissa, Kabweru, Wilberforce, Kayondo, Willy, Mbabazi, Stacy K., Kibuuka, Hannah, Kimuli, Ivan, Mulei, Sophie, Mutegeki, Michael, Emmanuel, Batibwe, Mwebesa, Henry, Naluyima, Prossy, Okello, Stephen, Tumusiime, Alex, Montgomery, Joel, Vasireddy, Vamsi, Olaro, Charles, Wayengera, Misaki, Lamorde, Mohammed

“…An Ebola outbreak occurred in Uganda in 2022. This letter reports transmission to health care workers in the nosocomial setting…”
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Safety and Immunogenicity of Accelerated Heterologous 2-Dose Ebola Vaccine Regimens in Adults With and Without Human Immunodeficiency Virus in Africa by Mwesigwa, Betty, Sawe, Fredrick, Oyieko, Janet, Mwakisisile, Joel, Viegas, Edna, Akintunde, Gideon Akindiran, Kosgei, Josphat, Kokogho, Afoke, Ntinginya, Nyanda, Jani, Ilesh, Shukarev, Georgi, Hooper, Jay W, Kwilas, Steven A, Ward, Lucy A, Rusnak, Janice, Bounds, Callie, Overman, Rachel, Badorrek, Christopher S, Eller, Leigh Anne, Eller, Michael A, Polyak, Christina S, Moodley, Amber, Tran, Chi L, Costanzo, Margaret C, Leggat, David J, Paquin-Proulx, Dominic, Naluyima, Prossy, Anumendem, Dickson Nkafu, Gaddah, Auguste, Luhn, Kerstin, Hendriks, Jenny, McLean, Chelsea, Douoguih, Macaya, Kibuuka, Hannah, Robb, Merlin L, Robinson, Cynthia, Ake, Julie A

“…Abstract Background Shorter prophylactic vaccine schedules may offer more rapid protection against Ebola in resource-limited settings. Methods This randomized,…”
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Transient Reductions in Human Immunodeficiency Virus (HIV) Clinic Attendance and Food Security During the Coronavirus Disease 2019 (COVID-19) Pandemic for People Living With HIV in 4 African Countries by Dear, Nicole, Duff, Emma, Esber, Allahna, Parikh, Ajay, Iroezindu, Michael, Bahemana, Emmanuel, Kibuuka, Hannah, Owuoth, John, Maswai, Jonah, Crowell, Trevor A, Ake, Julie A, Polyak, Christina S

“…Abstract The coronavirus disease 2019 (COVID-19) pandemic and associated public health responses have disrupted daily living activities with economic and…”
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Predictors of All-Cause Mortality Among People With Human Immunodeficiency Virus (HIV) in a Prospective Cohort Study in East Africa and Nigeria by Kibuuka, Hannah, Musingye, Ezra, Mwesigwa, Betty, Semwogerere, Michael, Iroezindu, Michael, Bahemana, Emmanuel, Maswai, Jonah, Owuoth, John, Esber, Allahna, Dear, Nicole, Crowell, Trevor A, Polyak, Christina S, Ake, Julie A

“…Introduction of antiretroviral therapy (ART) has been associated with a decline in human immunodeficiency virus (HIV)-related mortality, although HIV remains a…”
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Developing capacity for implementation and evaluation of vaccine trials in Uganda: Perspective of the Makerere University Walter Reed Project by Naluyima, Prossy, Mwesigwa, Betty, Tindikahwa, Allan, Mugamba, Stephen, Thaddeus Ssensamba, Jude, Musingye, Ezra, Mirembe, Grace, Kibuuka, Hannah, Wabwire-Mangen, Fred

“…Introduction: Infectious diseases and neglected tropical diseases continue to be a major challenge in resource limited settings, causing significant morbidity…”
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Cellular Immune Activation in Cerebrospinal Fluid From Ugandans With Cryptococcal Meningitis and Immune Reconstitution Inflammatory Syndrome by Meya, David B., Okurut, Samuel, Zziwa, Godfrey, Rolfes, Melissa A., Kelsey, Melander, Cose, Steve, Joloba, Moses, Naluyima, Prossy, Palmer, Brent E., Kambugu, Andrew, Mayanja-Kizza, Harriet, Bohjanen, Paul R., Eller, Michael A., Wahl, Sharon M., Boulware, David R., Manabe, Yuka C., Janoff, Edward N.

“…Background. Human immunodeficiency virus (HIV)-associated cryptococcal meningitis (CM) is characterized by high fungal burden and limited leukocyte trafficking…”
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Terminal Effector CD8 T Cells Defined by an IKZF2 + IL-7R - Transcriptional Signature Express FcγRIIIA, Expand in HIV Infection, and Mediate Potent HIV-Specific Antibody-Dependent Cellular Cytotoxicity by Naluyima, Prossy, Lal, Kerri G, Costanzo, Margaret C, Kijak, Gustavo H, Gonzalez, Veronica D, Blom, Kim, Eller, Leigh Anne, Creegan, Matthew, Hong, Ting, Kim, Dohoon, Quinn, Thomas C, Björkström, Niklas K, Ljunggren, Hans-Gustaf, Serwadda, David, Katabira, Elly T, Sewankambo, Nelson K, Gray, Ronald H, Baeten, Jared M, Michael, Nelson L, Wabwire-Mangen, Fred, Robb, Merlin L, Bolton, Diane L, Sandberg, Johan K, Eller, Michael A

“…HIV-1 infection expands large populations of late-stage differentiated CD8 T cells that may persist long after viral escape from TCR recognition. In this…”
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Differences in neutralizing antibody sensitivities and envelope characteristics indicate distinct antigenic properties of Nigerian HIV-1 subtype G and CRF02_AG by Wieczorek, Lindsay, Chang, David, Sanders-Buell, Eric, Zemil, Michelle, Martinez, Elizabeth, Schoen, Jesse, Chenine, Agnes-Laurence, Molnar, Sebastian, Barrows, Brittani, Poltavee, Kultida, Charurat, Man E, Abimiku, Alash'le, Blattner, William, Iroezindu, Michael, Kokogho, Afoke, Michael, Nelson L, Crowell, Trevor A, Ake, Julie A, Tovanabutra, Sodsai, Polonis, Victoria R

“…The magnitude of the HIV-1 epidemic in Nigeria is second only to the subtype C epidemic in South Africa, yet the subtypes prevalent in Nigeria require further…”
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Ontogeny of CD4 + T Lymphocytes with Phenotypic Susceptibility to HIV-1 during Exclusive and Non-Exclusive Breastfeeding in HIV-1-exposed Ugandan Infants by McFarland, Elizabeth J., Powell, Tina M., Onyango-Makumbi, Carolyne, Zhang, Weiming, Melander, Kelsey, Naluyima, Prossy, Okurut, Samuel, Eller, Michael A., Fowler, Mary Glenn, Janoff, Edward N.

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Ontogeny of CD4⁺ T Lymphocytes With Phenotypic Susceptibility to HIV-1 During Exclusive and Nonexclusive Breastfeeding in HIV-1–Exposed Ugandan Infants by McFarland, Elizabeth J., Powell, Tina M., Onyango-Makumbi, Carolyne, Zhang, Weiming, Melander, Kelsey, Naluyima, Prossy, Okurut, Samuel, Eller, Michael A., Fowler, Mary Glenn, Janoff, Edward N.

“…Background. Among infants exposed to human immunodeficiency virus (HIV) type 1, mixed breastfeeding is associated with higher postnatal HIV-1 transmission than…”
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Terminally differentiated CD8 effector T cells have NK-like features and are potent mediators of HIV-specific ADCC by Lal, Kerri G, Naluyima, Prossy, Costanzo, Margaret C, Kijak, Gustavo H, Eller, Leigh Anne, Creegan, Matthew, Michael, Nelson L, Robb, Merlin L, Bolton, Diane L, Sandberg, Johan K, Eller, Michael A.

“…Abstract Chronic viral infection and persistent antigenic stimulation is associated with a rise of late-stage differentiated CD8 T cells including a unique…”
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