Search Results - "Nalpas, C"

Circulating microRNAs as Potential Biomarkers of Infectious Disease by Correia, Carolina N, Nalpas, Nicolas C, McLoughlin, Kirsten E, Browne, John A, Gordon, Stephen V, MacHugh, David E, Shaughnessy, Ronan G

“…microRNAs (miRNAs) are a class of small non-coding endogenous RNA molecules that regulate a wide range of biological processes by post-transcriptionally…”
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MicroRNA profiling of the bovine alveolar macrophage response to Mycobacterium bovis infection suggests pathogen survival is enhanced by microRNA regulation of endocytosis and lysosome trafficking by Vegh, Peter, Magee, David A, Nalpas, Nicolas C, Bryan, Kenneth, McCabe, Matthew S, Browne, John A, Conlon, Kevin M, Gordon, Stephen V, Bradley, Daniel G, MacHugh, David E, Lynn, David J

“…Summary Mycobacterium bovis , the causative agent of bovine tuberculosis, a major problem for global agriculture, spreads via an airborne route and is taken up…”
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Efficacy and safety of Simeprevir-containing hepatitis C therapy in patients on opiate substitution therapy by Dillon, J, Mauss, S, Nalpas, C, Bicer, C, Schlag, M, Lonjon-Domanec, I, Jessner, W, Beumont-Mauviel, M, Kalmeijer, R

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RNA Sequencing (RNA-Seq) Reveals Extremely Low Levels of Reticulocyte-Derived Globin Gene Transcripts in Peripheral Blood From Horses ( Equus caballus ) and Cattle ( Bos taurus ) by Correia, Carolina N, McLoughlin, Kirsten E, Nalpas, Nicolas C, Magee, David A, Browne, John A, Rue-Albrecht, Kevin, Gordon, Stephen V, MacHugh, David E

“…RNA-seq has emerged as an important technology for measuring gene expression in peripheral blood samples collected from humans and other vertebrate species. In…”
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RNA-seq Transcriptional Profiling of Peripheral Blood Leukocytes from Cattle Infected with Mycobacterium bovis by McLoughlin, Kirsten E, Nalpas, Nicolas C, Rue-Albrecht, Kévin, Browne, John A, Magee, David A, Killick, Kate E, Park, Stephen D E, Hokamp, Karsten, Meade, Kieran G, O'Farrelly, Cliona, Gormley, Eamonn, Gordon, Stephen V, MacHugh, David E

“…Bovine tuberculosis, caused by infection with Mycobacterium bovis, is a major endemic disease affecting cattle populations worldwide, despite the…”
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Analysis of the Bovine Monocyte-Derived Macrophage Response to Mycobacterium avium Subspecies Paratuberculosis Infection Using RNA-seq by Casey, Maura E, Meade, Kieran G, Nalpas, Nicolas C, Taraktsoglou, Maria, Browne, John A, Killick, Kate E, Park, Stephen D E, Gormley, Eamonn, Hokamp, Karsten, Magee, David A, MacHugh, David E

“…Johne's disease, caused by infection with Mycobacterium avium subsp. paratuberculosis, (MAP), is a chronic intestinal disease of ruminants with serious…”
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Global gene expression and systems biology analysis of bovine monocyte-derived macrophages in response to in vitro challenge with Mycobacterium bovis by Magee, David A, Taraktsoglou, Maria, Killick, Kate E, Nalpas, Nicolas C, Browne, John A, Park, Stephen D E, Conlon, Kevin M, Lynn, David J, Hokamp, Karsten, Gordon, Stephen V, Gormley, Eamonn, MacHugh, David E

“…Mycobacterium bovis, the causative agent of bovine tuberculosis, is a major cause of mortality in global cattle populations. Macrophages are among the first…”
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Pan-genomic analysis of bovine monocyte-derived macrophage gene expression in response to in vitro infection with Mycobacterium avium subspecies paratuberculosis by Machugh, David E, Taraktsoglou, Maria, Killick, Kate E, Nalpas, Nicolas C, Browne, John A, DE Park, Stephen, Hokamp, Karsten, Gormley, Eamonn, Magee, David A

“…Mycobacterium avium subspecies paratuberculosis is the causative agent of Johne's disease, an intestinal disease of ruminants with major economic consequences…”
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RNA-Seq Transcriptome Analysis of Peripheral Blood From Cattle Infected With Mycobacterium bovis Across an Experimental Time Course by McLoughlin, Kirsten E., Correia, Carolina N., Browne, John A., Magee, David A., Nalpas, Nicolas C., Rue-Albrecht, Kevin, Whelan, Adam O., Villarreal-Ramos, Bernardo, Vordermeier, H. Martin, Gormley, Eamonn, Gordon, Stephen V., MacHugh, David E.

“…Bovine tuberculosis, caused by infection with members of the Mycobacterium tuberculosis complex, particularly Mycobacterium bovis , is a major endemic disease…”
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Comparative functional genomics and the bovine macrophage response to strains of the mycobacterium genus by Rue-Albrecht, Kévin, Magee, David A, Killick, Kate E, Nalpas, Nicolas C, Gordon, Stephen V, MacHugh, David E

“…Mycobacterial infections are major causes of morbidity and mortality in cattle and are also potential zoonotic agents with implications for human health…”
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Key Hub and Bottleneck Genes Differentiate the Macrophage Response to Virulent and Attenuated Mycobacterium bovis by Killick, Kate E, Magee, David A, Park, Stephen D E, Taraktsoglou, Maria, Browne, John A, Conlon, Kevin M, Nalpas, Nicolas C, Gormley, Eamonn, Gordon, Stephen V, MacHugh, David E, Hokamp, Karsten

“…Mycobacterium bovis is an intracellular pathogen that causes tuberculosis in cattle. Following infection, the pathogen resides and persists inside host…”
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Quantitative Proteomics Links the Intermediate Filament Nestin to Resistance to Targeted BRAF Inhibition in Melanoma Cells[S] by Schmitt, Marisa, Sinnberg, Tobias, Nalpas, Nicolas C., Maass, Annika, Schittek, Birgit, Macek, Boris

“…The proteome and phosphoproteome have been determined for BRAF inhibitor resistant and sensitive cells by applying quantitative MS-based proteomics. We…”
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Proteogenomics Reveals Perturbed Signaling Networks in Malignant Melanoma Cells Resistant to BRAF Inhibition by Schmitt, Marisa, Sinnberg, Tobias, Bratl, Katrin, Zittlau, Katharina, Garbe, Claus, Macek, Boris, Nalpas, Nicolas C.

“…Analysis of nucleotide variants is a cornerstone of cancer medicine. Although only 2% of the genomic sequence is protein coding, mutations occurring in these…”
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Parallel reaction monitoring on a Q Exactive mass spectrometer increases reproducibility of phosphopeptide detection in bacterial phosphoproteomics measurements by Taumer, Christoph, Griesbaum, Lena, Kovacevic, Alen, Soufi, Boumediene, Nalpas, Nicolas C., Macek, Boris

“…Increasing number of studies report the relevance of protein Ser/Thr/Tyr phosphorylation in bacterial physiology, yet the analysis of this type of modification…”
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In-depth analysis of Bacillus subtilis proteome identifies new ORFs and traces the evolutionary history of modified proteins by Ravikumar, Vaishnavi, Nalpas, Nicolas C., Anselm, Viktoria, Krug, Karsten, Lenuzzi, Maša, Šestak, Martin Sebastijan, Domazet-Lošo, Tomislav, Mijakovic, Ivan, Macek, Boris

“…Bacillus subtilis is a sporulating Gram-positive bacterium widely used in basic research and biotechnology. Despite being one of the best-characterized…”
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Individualized Proteogenomics Reveals the Mutational Landscape of Melanoma Patients in Response to Immunotherapy by Schmitt, Marisa, Sinnberg, Tobias, Niessner, Heike, Forschner, Andrea, Garbe, Claus, Macek, Boris, Nalpas, Nicolas C.

“…Immune checkpoint inhibitors are used to restore or augment antitumor immune responses and show great promise in the treatment of melanoma and other types of…”
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Proteome Response of a Metabolically Flexible Anoxygenic Phototroph to Fe(II) Oxidation by Bryce, Casey, Franz-Wachtel, Mirita, Nalpas, Nicolas C, Miot, Jennyfer, Benzerara, Karim, Byrne, James M, Kleindienst, Sara, Macek, Boris, Kappler, Andreas

“…The oxidation of Fe(II) by anoxygenic photosynthetic bacteria was likely a key contributor to Earth's biosphere prior to the evolution of oxygenic…”
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High-resolution transcriptomics of bovine purified protein derivative-stimulated peripheral blood from cattle infected with Mycobacterium bovis across an experimental time course by Correia, Carolina N., McHugo, Gillian P., Browne, John A., McLoughlin, Kirsten E., Nalpas, Nicolas C., Magee, David A., Whelan, Adam O., Villarreal-Ramos, Bernardo, Vordermeier, H. Martin, Gormley, Eamonn, Gordon, Stephen V., MacHugh, David E.

“…Improved bovine tuberculosis (bTB) diagnostics with higher sensitivity and specificity are urgently required. A better understanding of the peripheral blood…”
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GOexpress: an R/Bioconductor package for the identification and visualisation of robust gene ontology signatures through supervised learning of gene expression data by Rue-Albrecht, Kévin, McGettigan, Paul A, Hernández, Belinda, Nalpas, Nicolas C, Magee, David A, Parnell, Andrew C, Gordon, Stephen V, MacHugh, David E

“…Identification of gene expression profiles that differentiate experimental groups is critical for discovery and analysis of key molecular pathways and also for…”
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RNA sequencing provides exquisite insight into the manipulation of the alveolar macrophage by tubercle bacilli by Nalpas, Nicolas C., Magee, David A., Conlon, Kevin M., Browne, John A., Healy, Claire, McLoughlin, Kirsten E., Rue-Albrecht, Kévin, McGettigan, Paul A., Killick, Kate E., Gormley, Eamonn, Gordon, Stephen V., MacHugh, David E.

“…Mycobacterium bovis , the agent of bovine tuberculosis, causes an estimated $3 billion annual losses to global agriculture due, in part, to the limitations of…”
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