Search Results - "Naldini, A"
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Carbonic anhydrase XII expression is linked to suppression of Sonic hedgehog ligand expression in triple negative breast cancer cells
Published in Biochemical and biophysical research communications (20-08-2019)“…Aberrant activity of the hedgehog (Hh) pathway is prevalent in pathologies such as cancer. Improved understanding of Hh activity in the aggressive tumor cell…”
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Indocyanine green fluorescence applied to gynecologic oncology: beyond sentinel lymph node
Published in International journal of surgery (London, England) (15-03-2024)“…Indocyanine green (ICG), a well-known molecule employed in medicine for over five decades, has emerged as a versatile dye widely embraced across various…”
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Role of the hypoxic microenvironment in the antitumor activity of tyrosine kinase inhibitors
Published in Current medicinal chemistry (01-06-2011)“…The tumor microenvironment is characterized, not only by marked gradients in drug concentration, but also by gradients in the rate of cell proliferation and by…”
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Secondary cytoreduction plus oxaliplatin-based HIPEC in platinum-sensitive recurrent ovarian cancer patients: A pilot study
Published in Gynecologic oncology (01-06-2009)“…Abstract Objectives To assess feasibility, complications and efficacy of secondary surgical cytoreduction (CRS) and hyperthermic intraperitoneal chemotherapy…”
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Analysis of protease-activated receptor-1 and -2 in human scar formation
Published in The Journal of pathology (01-08-2007)“…Protease‐activated receptor (PAR)‐1 and PAR‐2 are reported to contribute to the fibrotic process in a number of organs, including lung, liver, pancreas, and…”
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New pyrazolo[3,4- d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation
Published in Bioorganic & medicinal chemistry letters (17-05-2004)“…New 4-aminopyrazolo[3,4- d]pyrimidines substituted in positions 1 and 6 have been reported. Compounds showed A431 antiproliferative activity and inhibition of…”
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Role of different approaches to the abdominal retroperitoneum for aortic lymphadenectomy in patients with gynecological cancers
Published in European journal of surgical oncology (01-01-2013)“…Abstract Background Paraaortic lymphadenectomy (PALN) is a standard part of many interventions, but currently there are no established care protocols effective…”
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Regulation of angiogenesis by Th1- and Th2-type cytokines
Published in Current pharmaceutical design (01-01-2003)“…Angiogenesis is a complex process, where several cell types and mediators interact to establish a specific microenvironment suitable for the formation of new…”
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Inhibition of interleukin‐12 expression by α‐thrombin in human peripheral blood mononuclear cells: a potential mechanism for modulating Th1/Th2 responses
Published in British journal of pharmacology (01-11-2003)“…In addition to its central role in blood coagulation and hemostasis, human α‐thrombin is a powerful regulator of inflammatory responses and is known to affect…”
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Phase II study of pegylated liposomal doxorubicin in heavily pretreated epithelial ovarian cancer patients. May a new treatment schedule improve toxicity profile?
Published in Oncology (01-01-2004)“…Pegylated liposomal doxorubicin (PLD) has shown promising activity in the treatment of recurrent ovarian cancer but skin toxicity remains the dose-limiting…”
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Endometrioid adenocarcinoma with squamous differentiation arising from ureteral endometriosis in a patient with no history of gonadal endometriosis
Published in Gynecologic oncology (01-12-2005)“…Malignant transformation may occur in up to 1% of women with endometriosis and only 20% of these cases occur at extragonadal pelvic sites. Similarly, urinary…”
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OC-05 Protease-activated receptor-1 (PAR-1) expression correlates with a malignant phenotype in human melanoma
Published in Thrombosis research (2007)Get full text
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The new surgical robot Hugo™ RAS for total hysterectomy: a pilot study
Published in Facts, views & vision in ObGyn (01-12-2023)“…With the rising popularity of robotic surgery, Hugo™ RAS is one of the newest surgical robotic platforms. Investigating the reliability of this tool is the…”
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Heparin coating of extracorporeal circuits inhibits cytokine release from mononuclear cells during cardiac operations
Published in International journal of artificial organs (01-04-2000)“…To evaluate whether the production of interleukin 2 (IL 2), interleukin 6 (IL 6) and interleukin 10 (IL 10) from stimulated peripheral blood mononuclear cells…”
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Identification of thrombin-like activity in ovarian cancer associated ascites and modulation of multiple cytokine networks
Published in Thrombosis and haemostasis (01-10-2011)“…Blood coagulation cascades can be activated by different mechanisms and to different levels in cancer patients. In a study conducted on the transcriptional…”
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Plasma levels of immunosuppressive mediators during cardiopulmonary bypass
Published in Mediators of Inflammation (1996)“…THE aim of this study was to evaluate plasma levels of two mediators with immunosuppressive properties, complement fraction C3a (C3a) and transforming growth…”
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Pyrazolo[3,4-d]pyrimidines as Potent Antiproliferative and Proapoptotic Agents toward A431 and 8701-BC Cells in Culture via Inhibition of c-Src Phosphorylation
Published in Journal of medicinal chemistry (09-03-2006)“…We report here the synthesis of new pyrazolo[3,4-d]pyrimidine derivatives along with their biological properties as inhibitors of isolated Src and cell line…”
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