Search Results - "Nalawade, Sachin A"

A cationic amphiphilic peptide chaperone rescues Aβ42 aggregation and cytotoxicity by Puneeth Kumar, DRGKoppalu R, Reja, Rahi M, Senapati, Dillip K, Singh, Manjeet, Nalawade, Sachin A, George, Gijo, Kaul, Grace, Akhir, Abdul, Chopra, Sidharth, Raghothama, Srinivasarao, Gopi, Hosahudya N

“…Directing Aβ42 to adopt a conformation that is free from aggregation and cell toxicity is an attractive and viable strategy to design therapeutics for…”
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HBTU Mediated Synthesis of α,β‐Unsaturated γ‐Lactams from E ‐α,β‐Unsaturated γ‐Amino Acids by Singh, Manjeet, Nalawade, Sachin A., Kumar, DRGKoppalu. R. Puneeth, Veeresh, Kuruva, Pahan, Saikat, Dey, Sanjit, Gopi, Hosahudya N.

“…Abstract The α,β‐unsaturated γ‐lactams have been found in many biologically active peptide natural products. Due to their biological activities, extensive…”
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Direct Transformation of N‑Protected α,β-Unsaturated γ‑Amino Amides into γ‑Lactams through a Base-Mediated Molecular Rearrangement by Ganesh Kumar, Mothukuri, Veeresh, Kuruva, Nalawade, Sachin A, Nithun, Raj V, Gopi, Hosahudya N

“…Here, we are reporting a single-step transformation of N-protected α,β-unsaturated γ-amino amides into 5,5-disubstituted γ-lactams through a base-mediated new…”
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Proteolytically Stable ααγ-Hybrid Peptides Inhibit the Aggregation and Cytotoxicity of Aβ42 by Puneeth Kumar, DRGKoppalu R., Nalawade, Sachin A., Pahan, Saikat, Singh, Manjeet, Senapati, Dillip K., Roy, Souvik, Dey, Sanjit, Toraskar, Sandip U., Raghothama, Srinivasarao, Gopi, Hosahudya N.

“…The recent approval of antibody-based therapy for targeting the clearance of amyloid plaques fuels the research in designing small molecules and peptide…”
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A cationic amphiphilic peptide chaperone rescues Aβ 42 aggregation and cytotoxicity by Puneeth Kumar, DRGKoppalu R, Reja, Rahi M, Senapati, Dillip K, Singh, Manjeet, Nalawade, Sachin A, George, Gijo, Kaul, Grace, Akhir, Abdul, Chopra, Sidharth, Raghothama, Srinivasarao, Gopi, Hosahudya N

“…Directing Aβ to adopt a conformation that is free from aggregation and cell toxicity is an attractive and viable strategy to design therapeutics for…”
Get full text

Proteolytically Stable ααγ-Hybrid Peptides Inhibit the Aggregation and Cytotoxicity of Aβ 42 by Puneeth Kumar, DRGKoppalu R., Nalawade, Sachin A., Pahan, Saikat, Singh, Manjeet, Senapati, Dillip K., Roy, Souvik, Dey, Sanjit, Toraskar, Sandip U., Raghothama, Srinivasarao, Gopi, Hosahudya N.

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A cationic amphiphilic peptide chaperone rescues Aβ aggregation and cytotoxicity by Puneeth Kumar, DRGKoppalu R, Reja, Rahi M, Senapati, Dillip K, Singh, Manjeet, Nalawade, Sachin A, George, Gijo, Kaul, Grace, Akhir, Abdul, Chopra, Sidharth, Raghothama, Srinivasarao, Gopi, Hosahudya N

“…Directing Aβ 42 to adopt a conformation that is free from aggregation and cell toxicity is an attractive and viable strategy to design therapeutics for…”
Get full text