Search Results - "Nakiyingi, Lydia"

Sputum microbiota profiles of treatment-naïve TB patients in Uganda before and during first-line therapy by Kateete, David Patrick, Mbabazi, Monica M., Nakazzi, Faith, Katabazi, Fred A., Kigozi, Edgar, Ssengooba, Willy, Nakiyingi, Lydia, Namiiro, Sharon, Okwera, Alphonse, Joloba, Moses L., Muwonge, Adrian

“…Information on microbiota dynamics in pulmonary tuberculosis (TB) in Africa is scarce. Here, we sequenced sputa from 120 treatment-naïve TB patients in Uganda,…”
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Effect of mixed Mycobacterium tuberculosis infection on rapid molecular diagnostics among patients starting MDR-TB treatment in Uganda by Komakech, Kevin, Nakiyingi, Lydia, Fred, Ashab, Achan, Beatrice, Joloba, Moses, Kirenga, Bruce J, Ssengooba, Willy

“…Mixed M. tuberculosis (MTB) infection occurs when one is infected with more than one clonally distinct MTB strain. This form of infection can assist MTB…”
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Determinants of QuantiFERON Plus-diagnosed tuberculosis infection in adult Ugandan TB contacts: A cross-sectional study by Mayito, Jonathan, Martineau, Adrian R, Tiwari, Divya, Nakiyingi, Lydia, Kateete, David P, Reece, Stephen T, Biraro, Irene Andia

“…The tuberculin skin test is commonly used to diagnose latent tuberculosis infection (LTBI) in resource-limited settings, but its specificity is limited by…”
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Antiretroviral therapy initiation and outcomes of hospitalized HIV-infected patients in Uganda—An evaluation of the HIV test and treat strategy by Katende, Andrew, Nakiyingi, Lydia, Andia-Biraro, Irene, Katairo, Thomas, Muhumuza, Richard, Ssemata, Andrew S, Nsereko, Christopher, Semitala, Fred C, Meya, David B

“…Background Uganda adopted the HIV Test and Treat in 2016. There is paucity of data about its implementation among hospitalized patients. We aimed to determine…”
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Misdiagnosis of chronic pulmonary aspergillosis as pulmonary tuberculosis at a tertiary care center in Uganda: a case series by Kwizera, Richard, Katende, Andrew, Bongomin, Felix, Nakiyingi, Lydia, Kirenga, Bruce J

“…Diagnosis of chronic pulmonary aspergillosis (CPA) is based on a combination of clinical symptomatology, compatible chest imaging findings, evidence of…”
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Chest X-ray interpretation does not complement Xpert MTB/RIF in diagnosis of smear-negative pulmonary tuberculosis among TB-HIV co-infected adults in a resource-limited setting by Nakiyingi, Lydia, Bwanika, John Mark, Ssengooba, Willy, Mubiru, Frank, Nakanjako, Damalie, Joloba, Moses L, Mayanja-Kizza, Harriet, Manabe, Yukari C

“…Chest X-ray (CXR) interpretation remains a central component of the current World Health Organization recommendations as an adjuvant test in diagnosis of…”
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Cardiovascular risk factors among people with drug-resistant tuberculosis in Uganda by Baluku, Joseph Baruch, Nabwana, Martin, Nalunjogi, Joanitah, Muttamba, Winters, Mubangizi, Ivan, Nakiyingi, Lydia, Ssengooba, Willy, Olum, Ronald, Bongomin, Felix, Andia-Biraro, Irene, Worodria, William

“…Tuberculosis (TB) and its risk factors are independently associated with cardiovascular disease (CVD). We determined the prevalence and associations of CVD…”
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Performance of loop-mediated isothermal amplification assay in the diagnosis of pulmonary tuberculosis in a high prevalence TB/HIV rural setting in Uganda by Nakiyingi, Lydia, Nakanwagi, Prossy, Briggs, Jessica, Agaba, Tifu, Mubiru, Frank, Mugenyi, Mark, Ssengooba, Willy, Joloba, Moses L, Manabe, Yukari C

“…Smear microscopy lacks sensitivity especially in HIV co-infection, resulting in undiagnosed tuberculosis (TB) and high mortality. The loop-mediated isothermal…”
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"Tuberculosis in advanced HIV infection is associated with increased expression of IFNγ and its downstream targets" by Verma, Sheetal, Du, Peicheng, Nakanjako, Damalie, Hermans, Sabine, Briggs, Jessica, Nakiyingi, Lydia, Ellner, Jerrold J, Manabe, Yukari C, Salgame, Padmini

“…Tuberculosis (TB) is the major cause of death in Human Immunodeficiency Virus (HIV)-infected individuals. However, diagnosis of TB in HIV remains challenging…”
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Point-of-care lateral flow assays for tuberculosis and cryptococcal antigenuria predict death in HIV infected adults in Uganda by Manabe, Yukari C, Nonyane, Bareng A S, Nakiyingi, Lydia, Mbabazi, Olive, Lubega, Gloria, Shah, Maunank, Moulton, Lawrence H, Joloba, Moses, Ellner, Jerrold, Dorman, Susan E

“…Mortality in hospitalized, febrile patients in Sub-Saharan Africa is high due to HIV-infected, severely immunosuppressed patients with opportunistic…”
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Recurrent pneumothorax in a human immunodeficiency virus-positive patient with multidrug-resistant tuberculosis: a rare case of bronchopleural fistula: a case report by Nakiyingi, Lydia, Baluku, Joseph Baruch, Ssengooba, Willy, Namiiro, Sharon Miriam, Buyego, Paul, Kimuli, Ivan, Adakun, Susan

“…Human immunodeficiency virus/tuberculosis coinfections have amplified the multidrug-resistant tuberculosis pandemic in many countries in Sub-Saharan Africa,…”
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Evaluation of Cepheid's Xpert MTB/Rif test on pleural fluid in the diagnosis of pleural tuberculosis in a high prevalence HIV/TB setting by Lusiba, John K, Nakiyingi, Lydia, Kirenga, Bruce J, Kiragga, Agnes, Lukande, Robert, Nsereko, Maria, Ssengooba, Willy, Katamba, Achilles, Worodria, William, Joloba, Moses L, Mayanja-Kizza, Harriet

“…Diagnosis of pleural tuberculosis (TB) using routinely available diagnostic methods is challenging due to the paucibacillary nature of the disease…”
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Clinical predictors and accuracy of empiric tuberculosis treatment among sputum smear-negative HIV-infected adult TB suspects in Uganda by Nakiyingi, Lydia, Bwanika, John Mark, Kirenga, Bruce, Nakanjako, Damalie, Katabira, Catherine, Lubega, Gloria, Sempa, Joseph, Nyesiga, Barnabas, Albert, Heidi, Manabe, Yukari C

“…The existing diagnostic algorithms for sputum smear-negative tuberculosis (TB) are complicated, time-consuming, and often difficult to implement. The decision…”
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SARS-CoV-2-Associated Multisystem Inflammatory Syndrome in a Child in Uganda: A Paediatric Experience in a Resource-Limited Setting by Piloya, Thereza, Nakiyingi, Lydia, Kimuli, Ivan, Kayima, James, Lubega, Joseph, Sekabira, John, Aanyu, Hellen T.

“…SARS-CoV-2-associated Multisystem Inflammatory Syndrome in children (MIS-C) has been described in developed settings that have reported a high burden of…”
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Prevalence and predictors of ocular complications among children undergoing nephrotic syndrome treatment in a resource-limited setting by Nakubulwa, Faith, Lusobya, Rebecca Claire, Batte, Anthony, Ssuna, Bashir, Nakanjako, Damalie, Nakiyingi, Lydia, Nalukenge, Caroline, Sebabi, Francis Onen, Mulinde, Ben, Otiti-Sengeri, Juliet

“…Nephrotic syndrome is the most common glomerulopathy among children aged 2-18 years and high dose corticosteroids are the backbone of its management…”
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Towards Improved Management of Tuberculous Bloodstream Infections: Pharmacokinetic Considerations with Suggestions for Better Treatment Outcomes by Odongo, Charles Okot, Nakiyingi, Lydia, Nkeramihigo, Clovis Gatete, Seifu, Daniel, Bisaso, Kuteesa Ronald

“…Mycobacterium tuberculosis is the leading cause of sepsis among HIV-infected adults, yet effective treatment remains a challenge. Efficacy of antituberculous…”
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Diagnostic accuracy of the NOVA Tuberculosis Total Antibody Rapid test for detection of pulmonary tuberculosis and infection with Mycobacterium tuberculosis by Nsubuga, Gideon, Kennedy, Samuel, Rani, Yasha, Hafiz, Zibran, Kim, Soyeon, Ruhwald, Morten, Alland, David, Ellner, Jerrold, Joloba, Moses, Dorman, Susan E., Penn-Nicholson, Adam, Nakiyingi, Lydia

“…The NOVA Tuberculosis Total Antibody Rapid Test is a commercially available lateral flow serological assay that is intended to be used as an aid in the…”
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Predictors and outcomes of mycobacteremia among HIV-infected smear- negative presumptive tuberculosis patients in Uganda by Nakiyingi, Lydia, Ssengooba, Willy, Nakanjako, Damalie, Armstrong, Derek, Holshouser, Molly, Kirenga, Bruce J, Shah, Maunank, Mayanja-Kizza, Harriet, Joloba, Moses L, Ellner, Jerrold J, Dorman, Susan E, Manabe, Yukari C

“…Sputum smear microscopy for tuberculosis (TB) diagnosis lacks sensitivity in HIV-infected symptomatic patients and increases the likelihood that mycobacterial…”
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Clinical presentation and outcomes in children with retinoblastoma managed at the Uganda Cancer Institute by Kalinaki, Abubakar, Muwonge, Haruna, Balagadde-Kambugu, Joyce, Mulumba, Yusuf, Ntende, Jacob, Ssali, Grace, Nakiyingi, Lydia, Nakanjako, Damalie, Nalukenge, Caroline, Ampaire, Anne M.

“…Background. The majority of patients with retinoblastoma, the most common intraocular cancer of childhood, are found in low-and middle-income countries…”
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High Genotypic Discordance of Concurrent Mycobacterium tuberculosis Isolates from Sputum and Blood of HIV-Infected Individuals by Ssengooba, Willy, Cobelens, Frank G, Nakiyingi, Lydia, Mboowa, Gerald, Armstrong, Derek T, Manabe, Yukari C, Joloba, Moses L, de Jong, Bouke C

“…Among HIV-infected individuals with CD4 less than 200 cells/mm3, tuberculosis often has an atypical presentation, is more likely to be disseminated and is…”
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