Detection of halitosis in breath: Between the past, present, and future

Detection of halitosis in breath: Between the past, present, and future

To develop a new generation of diagnostics for halitosis, replacing the subjective organoleptic assessment, a series of exhaled breath analyzers has been developed and assessed. All three devices rely on the assessment of exhaled volatile sulfuric compounds (VSCs), which are mainly generated in and...

Full description

Saved in:
Bibliographic Details
Published in:Oral diseases Vol. 24; no. 5; pp. 685 - 695
Main Authors: Nakhleh, MK, Quatredeniers, M, Haick, H
Format: Journal Article
Language:English
Published: Denmark Wiley Subscription Services, Inc 01-07-2018
Wiley
Subjects:
artificial intelligence
Dentistry
halitosis
Life Sciences
Off odor
Olfaction
Oral cavity
sensor array
Sulfur
Systemic diseases
volatile compounds
volatolome
volatile compounds
volatolome
artificial intelligence
sensor array
halitosis
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To develop a new generation of diagnostics for halitosis, replacing the subjective organoleptic assessment, a series of exhaled breath analyzers has been developed and assessed. All three devices rely on the assessment of exhaled volatile sulfuric compounds (VSCs), which are mainly generated in and emitted from the oral cavity, contributing to the malodor. Portable, on‐site and easy to use, these devices have potential for non‐invasive diagnosis of halitosis. However, global assessment of exhaled VSCs alone has two main drawbacks: (i) the absence of VSCs does not rule out halitosis; (ii) non‐sulfuric volatile compounds that could be biomarkers of systemic diseases, found in up to 15% of halitosis cases, are neglected. In this article, we review and discuss progress to date in the field of oral/exhaled volatile compounds as potential non‐invasive diagnostics for halitosis. We will briefly describe the generation of these compounds both from local (oral) and distal (extra‐oral) sources. In addition, we debate the different analytical approaches in use and discuss the potential value of bio‐inspired artificially intelligent olfaction in diagnosing and classifying oral and systemic diseases by analyzing exhaled breath.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1354-523X
1601-0825
DOI:10.1111/odi.12699