Search Results - "Nakhasi, H"

Dermotropic Leishmania donovani in Sri Lanka: visceralizing potential in clinical and preclinical studies by Kariyawasam, K K G D U L, Selvapandiyan, A, Siriwardana, H V Y D, Dube, A, Karunanayake, P, Senanayake, S A S C, Dey, R, Gannavaram, S, Nakhasi, H L, Karunaweera, N D

“…The visceralizing potential of apparently dermotropic Leishmania donovani in Sri Lanka (L. donovani-SL) was investigated through long-term follow-up of…”
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Standardized methods to generate mock (spiked) clinical specimens by spiking blood or plasma with cultured pathogens by Dong, M., Fisher, C., Añez, G., Rios, M., Nakhasi, H.L., Hobson, J.P., Beanan, M., Hockman, D., Grigorenko, E., Duncan, R.

“…Aims To demonstrate standardized methods for spiking pathogens into human matrices for evaluation and comparison among diagnostic platforms. Methods and…”
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Programmed cell death in the unicellular protozoan parasite Leishmania by Lee, N, Bertholet, S, Debrabant, A, Muller, J, Duncan, R, Nakhasi, H L

“…In the present study we have demonstrated some features characterizing programmed cell death (PCD) in the unicellular protozoan parasite Leishmania donovani,…”
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Transcriptome analysis during the process of in vitro differentiation of Leishmania donovani using genomic microarrays by Srividya, G, Duncan, R, Sharma, P, Raju, B V S, Nakhasi, H L, Salotra, P

“…Leishmania donovani causes visceral disease (kala-azar), a major health problem throughout the tropics with 500 000 new cases every year. Leishmania…”
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Development of a Species-Specific PCR Assay for Detection of Leishmania donovani in Clinical Samples from Patients with Kala-Azar and Post-Kala-Azar Dermal Leishmaniasis by SALOTRA, Poonam, SREENIVAS, G, POGUE, Gregory P, LEE, Nancy, NAKHASI, Hira L, RAMESH, V, NEGI, N. S

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Programmed cell death in trypanosomatids and other unicellular organisms by Debrabant, Alain, Lee, Nancy, Bertholet, Sylvie, Duncan, Robert, Nakhasi, Hira L

“…In multicellular organisms, cellular growth and development can be controlled by programmed cell death (PCD), which is defined by a sequence of regulated…”
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Protein disulfide isomerase assisted protein folding in malaria parasites by Mahajan, B., Noiva, R., Yadava, A., Zheng, H., Majam, V., Mohan, K.V. Krishna, Moch, J.K., Haynes, J.D., Nakhasi, H., Kumar, S.

“…In eukaryotes, the formation of protein disulfide bonds among cysteine residues is mediated by protein disulfide isomerases and occurs in the highly oxidised…”
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Centrin Gene Disruption Impairs Stage-specific Basal Body Duplication and Cell Cycle Progression in Leishmania by Selvapandiyan, Angamuthu, Debrabant, Alain, Duncan, Robert, Muller, Jacqueline, Salotra, Poonam, Sreenivas, Gannavaram, Salisbury, Jeffrey L., Nakhasi, Hira L.

“…Centrin is a calcium-binding cytoskeletal protein involved in the duplication of centrosomes in higher eukaryotes. To explore the role of centrin in the…”
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Transfusion-associated Babesia infections: Reports received by the FDA 1997 to 2008 by Gubernot, D, Lee, K.C, Conley, G.B, Holness, L.G, O’Callaghan, S, Cannon, S, Cowan, E, Nakhasi, H, Wise, R.P

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Identification of Calreticulin as a Rubella Virus RNA Binding Protein by Singh, Nishi K., Atreya, Chintamani D., Nakhasi, Hira L.

“…Previously, we observed that sequences at the 3' end of rubella virus (RV) genomic RNA that form a stable stem-loop structure are necessary for initiation of…”
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Rubella Virus E2 Signal Peptide Is Required for Perinuclear Localization of Capsid Protein and Virus Assembly by Law, L M, Duncan, R, Esmaili, A, Nakhasi, H L, Hobman, T C

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Rubella virus glycoprotein interaction with the endoplasmic reticulum calreticulin and calnexin by NAKHASI, H. L, RAMANUJAM, M, ATREYA, C. D, HOBMAN, T. C, LEE, N, ESMAILI, A, DUNCAN, R. C

“…Very little is known about the cellular factors that are required for the maturation of rubella virus glycoproteins (E2 and E1) in the endoplasmic reticulum of…”
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Expression of a Mutant Form of Leishmania donovani Centrin Reduces the Growth of the Parasite by Selvapandiyan, A, Duncan, R, Debrabant, A, Bertholet, S, Sreenivas, G, Negi, N S, Salotra, P, Nakhasi, H L

“…Leishmania donovani, a protozoan parasite, causes visceral disease in humans. To identify genes that control growth, we have isolated for the first time in the…”
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Cloning and characterization of differentially expressed genes from in vitro-grown 'amastigotes' of Leishmania donovani by Joshi, M, Dwyer, D M, Nakhasi, H L

“…Leishmanial parasites routinely undergo cyclic differentiation from promastigotes to amastigotes during their life cycle. This process involves both…”
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The application of gene expression microarray technology to kinetoplastid research by Duncan, Robert C, Salotra, Poonam, Goyal, Neena, Akopyants, Natalia S, Beverley, Stephen M, Nakhasi, Hira L

“…Protozoan parasites in the order Kinetoplastida cause severe disease primarily in tropical and subtropical areas. Vaccines to control these diseases have shown…”
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An Atypical Protein Disulfide Isomerase from the Protozoan Parasite Leishmania Containing a Single Thioredoxin-like Domain by Padilla, Alejandro, Noiva, Robert, Lee, Nancy, Mohan, Ketha V. Krishna, Nakhasi, Hira L., Debrabant, Alain

“…In higher eukaryotes, secretory proteins are under the quality control of the endoplasmic reticulum for their proper folding and release into the secretory…”
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DNA Polymorphism Assay Distinguishes Isolates of Leishmania donovani That Cause Kala-Azar from Those That Cause Post-Kala-Azar Dermal Leishmaniasis in Humans by SREENIVAS, Gannavaram, SUBBA RAJU, B. V, SINGH, Ruchi, SELVAPANDIYAN, Angamuthu, DUNCAN, Robert, SARKAR, Dwijen, NAKHASI, Hira L, SALOTRA, Poonam

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Expression of calreticulin P-domain results in impairment of secretory pathway in Leishmania donovani and reduced parasite survival in macrophages by Debrabant, Alain, Lee, Nancy, Pogue, Gregory P., Dwyer, Dennis M., Nakhasi, Hira L.

“…The secretory proteins of Leishmania are thought to be involved in the parasite survival inside the insect vector or mammalian host. It is clear from studies…”
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The rubella virus RNA binding activity of human calreticulin is localized to the N-terminal domain by Atreya, C D, Singh, N K, Nakhasi, H L

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Autoantigens interact with cis-acting elements of rubella virus RNA by Pogue, G P, Hofmann, J, Duncan, R, Best, J M, Etherington, J, Sontheimer, R D, Nakhasi, H L

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