Search Results - "Nakazato, A"

Synthesis, SARs, and Pharmacological Characterization of 2-Amino-3 or 6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Derivatives as Potent, Selective, and Orally Active Group II Metabotropic Glutamate Receptor Agonists by Nakazato, Atsuro, Kumagai, Toshihito, Sakagami, Kazunari, Yoshikawa, Ryoko, Suzuki, Yoshiko, Chaki, Shigeyuki, Ito, Hisanaka, Taguchi, Takeo, Nakanishi, Shigetada, Okuyama, Shigeru

“…(+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (4, LY354740), a highly selective and orally active group II metabotropic glutamate receptor (mGluR)…”
Get full text

Infrared focal plane array incorporating silicon IC process compatible bolometer by Tanaka, A., Matsumoto, S., Tsukamoto, N., Itoh, S., Chiba, K., Endoh, T., Nakazato, A., Okuyama, K., Kumazawa, Y., Hijikawa, M., Gotoh, H., Tanaka, T., Teranishi, N.

“…A 128/spl times/128 element bolometer infrared image sensor using thin film titanium is proposed. The device is a monolithically integrated structure with a…”
Get full text

The isolation of wall‐bound proteins regulating yield threshold tension in glycerinated hollow cylinders of cowpea hypocotyl by Okamoto‐Nakazato, A., Nakamura, T., Okamoto, H.

“…ABSTRACT To isolate and purify the factor regulating the yield threshold tension (y) through acidification of the cell wall, proteins were extracted from…”
Get full text

Involvement of corticotropin-releasing factor subtype 1 receptor in the acquisition phase of learned helplessness in rats by Takamori, K., Kawashima, N., Chaki, S., Nakazato, A., Kameo, K.

“…To determine if CRF receptor subtype 1 (CRF 1) is involved in the acquisition phase of LH, we administered CRF receptor antagonists, CRA1000 and CP-154,526, 60…”
Get full text

Molecular cloning of yieldins regulating the yield threshold of cowpea cell walls: cDNA cloning and characterization of recombinant yieldin by Okamoto‐Nakazato, A., Takahashi, K., Kido, N., Owaribe, K., Katou, K.

“…ABSTRACT cDNA for yieldin of Vigna unguiculata L. was cloned with reverse transcriptase‐polymerase chain reaction using synthetic oligonucleotides as primers…”
Get full text

Distribution of yieldin, a regulatory protein of the cell wall yield threshold, in etiolated cowpea [Vigna anguiculata] seedlings by Okamoto Nakazato, A. (Showa Pharmaceutical Univ., Tokyo (Japan)), Takahashi, K, Katoh Semba, R, Katou, K

“…We examined the distribution and the immunohistochemical localization of yieldin in etiolated cowpea seedlings with an anti-yieldin antibody. An immunoblotting…”
Get full text

"A brief note on the study of yieldin, a wall-bound protein that regulates the yield threshold of the cell wall." by "Okamoto Nakazato, A. (Showa Pharmaceutical Univ., Machida, Tokyo (Japan))."

“…"Yielding of plant-cell walls is defined by the mechanical properties of walls such as their extensibility (F for in vivo, f for in vitro cell wall) and yield…”
Get full text

A case of myasthenia gravis accompanied by erythema elevatum diutinum and rheumatoid arthritis by Wakata, N, Nakazato, A, Sugimoto, H, Iguchi, H, Saito, R

Get full text

Whole-Genome Sequencing of Sake Yeast Saccharomyces cerevisiae Kyokai no. 7 by Akao, Takeshi, Yashiro, Isao, Hosoyama, Akira, Kitagaki, Hiroshi, Horikawa, Hiroshi, Watanabe, Daisuke, Akada, Rinji, Ando, Yoshinori, Harashima, Satoshi, Inoue, Toyohisa, Inoue, Yoshiharu, Kajiwara, Susumu, Kitamoto, Katsuhiko, Kitamoto, Noriyuki, Kobayashi, Osamu, Kuhara, Satoru, Masubuchi, Takashi, Mizoguchi, Haruhiko, Nakao, Yoshihiro, Nakazato, Atsumi, Namise, Masahiro, Oba, Takahiro, Ogata, Tomoo, Ohta, Akinori, Sato, Masahide, Shibasaki, Seiji, Takatsume, Yoshifumi, Tanimoto, Shota, Tsuboi, Hirokazu, Nishimura, Akira, Yoda, Koji, Ishikawa, Takeaki, Iwashita, Kazuhiro, Fujita, Nobuyuki, Shimoi, Hitoshi

“…The term ‘sake yeast’ is generally used to indicate the Saccharomyces cerevisiae strains that possess characteristics distinct from others including the…”
Get full text

MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity by Chaki, Shigeyuki, Yoshikawa, Ryoko, Hirota, Shiho, Shimazaki, Toshiharu, Maeda, Maoko, Kawashima, Naoya, Yoshimizu, Takao, Yasuhara, Akito, Sakagami, Kazunari, Okuyama, Shigeru, Nakanishi, Shigetada, Nakazato, Atsuro

“…The present study describes the pharmacological profile of (1R,2R,3R,5R,6R)-2-Amino-3-(3,4-dichlorobenzyloxy)-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic…”
Get full text

Design, synthesis and structure-affinity relationships of aryloxyanilide derivatives as novel peripheral benzodiazepine receptor ligands by OKUBO, Taketoshi, YOSHIKAWA, Ryoko, CHAKI, Shigeyuki, OKUYAMA, Shigeru, NAKAZATO, Atsuro

“…Since the peripheral benzodiazepine receptor (PBR) has been primarily found as a high-affinity binding site for diazepam in rat kidney, numerous studies of it…”
Get full text

Anxiolytic- and antidepressant-like profile of a new CRF1 receptor antagonist, R278995/CRA0450 by CHAKI, Shigeyuki, NAKAZATO, Atsuro, KENNIS, Ludo, NAKAMURA, Masato, MACKIE, Claire, SUGIURA, Masayuki, VINKEN, Petra, ASHTON, David, LANGLOIS, Xavier, STECKLER, Thomas

“…1-[8-(2,4-dichlorophenyl)-2-methylquinolin-4-yl]-1,2,3,6-tetrahydropyridine-4-carboxamide benzenesulfonate (R278995/CRA0450) is a newly synthesized…”
Get full text

The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses psychomotor abnormalities and recognition memory deficits in mice lacking the pituitary adenylate cyclase-activating polypeptide by Ago, Yukio, Hiramatsu, Naoki, Ishihama, Toshihiro, Hazama, Keisuke, Hayata-Takano, Atsuko, Shibasaki, Yasuhiro, Shintani, Norihito, Hashimoto, Hitoshi, Kawasaki, Toshiyuki, Onoe, Hirotaka, Chaki, Shigeyuki, Nakazato, Atsuro, Baba, Akemichi, Takuma, Kazuhiro, Matsuda, Toshio

“…Previous studies suggest that metabotropic glutamate 2/3 receptors are involved in psychiatric disorders. In this study, we examined the effects of the…”
Get full text

Anxiolytic-like and antidepressant-like activities of MCL0129 (1-[(S)-2-(4-fluorophenyl)-2-(4-isopropylpiperadin-1-yl)ethyl]-4-[4-(2-methoxynaphthalen-1-yl)butyl]piperazine), a novel and potent nonpeptide antagonist of the melanocortin-4 receptor by Chaki, Shigeyuki, Hirota, Shiho, Funakoshi, Takeo, Suzuki, Yoshiko, Suetake, Sayoko, Okubo, Taketoshi, Ishii, Takaaki, Nakazato, Atsuro, Okuyama, Shigeru

“…We investigated the effects of a novel melanocortin-4 (MC4) receptor…”
Get more information

Neuropharmacological profiles of antagonists of group II metabotropic glutamate receptors by Kawashima, Naoya, Karasawa, Jun-ichi, Shimazaki, Toshiharu, Chaki, Shigeyuki, Okuyama, Shigeru, Yasuhara, Akito, Nakazato, Atsuro

“…Glutamatergic abnormalities play roles in several psychiatric disorders. Glutamate acts at two classes of receptors, ionotropic and metabotropic glutamate…”
Get full text

MCL0042: A nonpeptidic MC4 receptor antagonist and serotonin reuptake inhibitor with anxiolytic- and antidepressant-like activity by Chaki, Shigeyuki, Oshida, Yuichi, Ogawa, Shin-ichi, Funakoshi, Takeo, Shimazaki, Toshiharu, Okubo, Taketoshi, Nakazato, Atsuro, Okuyama, Shigeru

“…In the present study, we examined the anxiolytic and antidepressant effects of MCL0042, a novel compound showing activity in both MC4 receptor antagonism and…”
Get full text

Receptor binding, behavioral, and electrophysiological profiles of nonpeptide corticotropin-releasing factor subtype 1 receptor antagonists CRA1000 and CRA1001 by Okuyama, S, Chaki, S, Kawashima, N, Suzuki, Y, Ogawa, S, Nakazato, A, Kumagai, T, Okubo, T, Tomisawa, K

“…Receptor binding, behavioral, and electrophysiological profiles of 2-[N-(2-methylthio-4-isopropylphenyl)-N-ethylamino]-4-[4-(3-flu orophe…”
Get more information

Synthesis, in Vitro Pharmacology, Structure−Activity Relationships, and Pharmacokinetics of 3-Alkoxy-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Derivatives as Potent and Selective Group II Metabotropic Glutamate Receptor Antagonists by Nakazato, Atsuro, Sakagami, Kazunari, Yasuhara, Akito, Ohta, Hiroshi, Yoshikawa, Ryoko, Itoh, Manabu, Nakamura, Masato, Chaki, Shigeyuki

“…Novel group II metabotropic glutamate receptor (mGluR) antagonists, 3-alkoxy-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives 11 and 12,…”
Get full text

Design, synthesis, and structure–activity relationships of novel tetracyclic compounds as peripheral benzodiazepine receptor ligands by Okubo, Taketoshi, Yoshikawa, Ryoko, Chaki, Shigeyuki, Okuyama, Shigeru, Nakazato, Atsuro

“…Graphic The peripheral benzodiazepine receptor (PBR) is pharmacologically distinct from the central benzodiazepine receptor (CBR) and has been identified in a…”
Get full text

Polymerization of N-Propargylamides with a Rh−Vinyl Complex:  Confirmation of the Presence of Long-Lived Active Species by Nakazato, Atsushi, Saeed, Irfan, Shiotsuki, Masashi, Sanda, Fumio, Masuda, Toshio

“…The polymerization of N-propargylamides (HC⋮CCH2NHCOR, R = i-Pr (1), i-Bu (2), or n-Pen (3)) with a Rh vinyl complex (4) was examined. The polymerization of 2…”
Get full text