Search Results - "Nakaya, Takeo"
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VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid–liquid phase separation
Published in Nature communications (08-02-2023)“…Myofibroblasts cause tissue fibrosis by producing extracellular matrix proteins, such as collagens. Humoral factors like TGF-β, and matrix stiffness are…”
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Acute Interstitial Nephritis with Glomerular Capillary IgA Deposition Following SARS-CoV-2 mRNA Vaccination
Published in Internal Medicine (15-08-2023)“…We herein report a case of acute kidney injury (AKI) presenting as acute interstitial nephritis (AIN) after the first dose of the BNT162b2 mRNA vaccine against…”
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Case of immunoglobulin A vasculitis following coronavirus disease 2019 vaccination
Published in Journal of dermatology (01-12-2021)Get full text
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4
Activation of DNA Methyltransferase 1 by EBV Latent Membrane Protein 2A Leads to Promoter Hypermethylation of PTEN Gene in Gastric Carcinoma
Published in Cancer research (Chicago, Ill.) (01-04-2009)“…CpG island promoter methylation of tumor suppressor genes is one of the most characteristic abnormalities in EBV-associated gastric carcinoma (GC). Aberrant…”
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5
KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
Published in Cancer research (Chicago, Ill.) (15-05-2014)“…The intestinal epithelium maintains homeostasis by a self-renewal process involving resident stem cells, including Lgr5(+) crypt-base columnar cells, but core…”
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6
Immune Checkpoint Inhibitor-induced Pancreatitis with Pancreatic Enlargement Mimicking Autoimmune Pancreatitis: A Case Report and Review of the Literature
Published in Internal Medicine (15-03-2024)“…A 61-year-old woman was administered 35 cycles of pembrolizumab for the treatment of recurrent endometrial cancer, achieving a complete response. She presented…”
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Multifocal kaposiform hemangioendothelioma in multiple visceral organs: an autopsy of 9-day-old female baby
Published in Human pathology (01-08-2014)“…Summary Kaposiform hemangioendothelioma is a vascular tumor categorized as intermediate malignancy. We experienced an autopsy of a female baby with kaposiform…”
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8
Stimulation of cellular senescent processes, including secretory phenotypes and anti-oxidant responses, after androgen deprivation therapy in human prostate cancer
Published in The Journal of steroid biochemistry and molecular biology (01-01-2017)“…•Cellular senescence phenotypes are triggered by hormone ablation in an animal level.•Secretory phenotypes and anti-oxidant responses were accompanied in human…”
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9
Peptide mimetic NC114 induces growth arrest by preventing PKCδ activation and FOXM1 nuclear translocation in colorectal cancer cells
Published in FEBS open bio (01-04-2024)“…The peptide mimetic, NC114, is a promising anticancer compound that specifically kills colorectal cancer cells without affecting normal colon epithelial cells…”
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10
Pediatric angiomyxofibromatous tumor of the falx cerebri with locally destructive growth into the cranial bone
Published in Pathology international (01-02-2020)Get full text
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11
Development of Low-Molecular-Weight Compounds Targeting the Cancer-Associated KLF5 Transcription Factor
Published in ACS medicinal chemistry letters (14-04-2022)“…Krüppel-like factor 5 (KLF5) is a potential target for anticancer drugs. However, as an intrinsically disordered protein (IDP) whose tertiary structure cannot…”
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12
Ectopic respiratory mucosa in the skin which showed the repetitive distribution of ciliated bronchogenic epithelia and squamous metaplasia
Published in Journal of dermatology (01-11-2017)Get full text
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13
Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7
Published in FEBS letters (11-12-1998)“…The interferon regulatory factor (IRF) family of transcription factors regulate the interferon (IFN) system, among which IRF-3 is involved in the virus-induced…”
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14
Young–age‐onset pancreatoduodenal carcinoma in Shwachman–Diamond syndrome
Published in Pathology international (01-02-2014)“…Shwachman–Diamond syndrome, which is characterized by pancreatic fatty degeneration, skeletal growth retardation, and hematological dysfunction, is a…”
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15
Rapid Growth of Pelvic Cyst during Pregnancy: A Case Report
Published in Case reports in obstetrics and gynecology (2019)“…We describe a patient with bilateral cystic tumors of the pelvis. The left one rapidly grew during pregnancy and combined with the right one, whose clinical…”
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p600 Plays Essential Roles in Fetal Development
Published in PloS one (18-06-2013)“…p600 is a multifunctional protein implicated in cytoskeletal organization, integrin-mediated survival signaling, calcium-calmodulin signaling and the N-end…”
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Enrichment of stem-like cell population comprises transformation ability of Epstein–Barr virus latent membrane protein 2A for non-transformed cells
Published in Virus research (01-06-2013)“…•LMP2A, an EBV protein, -transferred-NIH3T3 causes visible tumors in nude mice.•LMP2A-expression increases Hoechst dye excreting side population (SP) in…”
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Gene Induction Pathways Mediated by Distinct IRFs during Viral Infection
Published in Biochemical and biophysical research communications (25-05-2001)“…During viral infection, interferon-α/β (IFN-α/β) and many IFN-inducible genes are induced to elicit antiviral responses of the host. Using cells with a gene…”
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Lymphatic Stomata in the Adult Human Pulmonary Ligament
Published in Lymphatic research and biology (01-06-2015)“…Lymphatic stomata are small lymphatic openings in the serosal membrane that communicate with the serosal cavity. Although these stomata have primarily been…”
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p600 regulates spindle orientation in apical neural progenitors and contributes to neurogenesis in the developing neocortex
Published in Biology open (08-05-2014)“…Apical neural progenitors (aNPs) drive neurogenesis by means of a program consisting of self-proliferative and neurogenic divisions. The balance between these…”
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