Search Results - "Nakatsuka, Yoshinari"
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Modified Citrus Pectin Prevents Blood-Brain Barrier Disruption in Mouse Subarachnoid Hemorrhage by Inhibiting Galectin-3
Published in Stroke (1970) (01-11-2018)“…BACKGROUND AND PURPOSE—Plasma levels of galectin-3—a matricellular protein—are increased after aneurysmal subarachnoid hemorrhage (SAH), but the functional…”
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2
Regnase-1 and Roquin Nonredundantly Regulate Th1 Differentiation Causing Cardiac Inflammation and Fibrosis
Published in The Journal of immunology (1950) (15-12-2017)“…Regnase-1 and Roquin are RNA binding proteins that are essential for degradation of inflammatory mRNAs and maintenance of immune homeostasis. Although…”
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3
Pseudomonas aeruginosa hijacks the murine nitric oxide metabolic pathway to evade killing by neutrophils in the lung
Published in Cell reports (Cambridge) (29-08-2023)“…Neutrophils play a critical role in the eradication of Pseudomonas aeruginosa, a major pathogen causing lung infection. However, the mechanisms used by the…”
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4
Tenascin‐C in brain injuries and edema after subarachnoid hemorrhage: Findings from basic and clinical studies
Published in Journal of neuroscience research (01-01-2020)“…Subarachnoid hemorrhage (SAH) by a rupture of cerebral aneurysms remains the most devastating cerebrovascular disease. Early brain injury (EBI) is increasingly…”
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5
Effects of Toll-Like Receptor 4 Antagonists Against Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage in Mice
Published in Molecular neurobiology (01-10-2017)“…Toll-like receptor 4 (TLR4) signaling may play a crucial role in the occurrence of cerebral vasospasm after subarachnoid hemorrhage (SAH). The main purpose of…”
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6
Profibrotic function of pulmonary group 2 innate lymphoid cells is controlled by regnase-1
Published in The European respiratory journal (01-03-2021)“…Regnase-1 is an RNase critical for post-transcriptional control of pulmonary immune homeostasis in mice by degrading immune-related mRNAs. However, little is…”
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7
Regnase-1 Prevents Pulmonary Arterial Hypertension Through mRNA Degradation of Interleukin-6 and Platelet-Derived Growth Factor in Alveolar Macrophages
Published in Circulation (New York, N.Y.) (27-09-2022)“…Pulmonary arterial hypertension (PAH) is a type of pulmonary hypertension (PH) characterized by obliterative pulmonary vascular remodeling, resulting in…”
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Preventive effects of cilostazol against the development of shunt-dependent hydrocephalus after subarachnoid hemorrhage
Published in Journal of neurosurgery (01-08-2017)“…OBJECTIVE Chronic hydrocephalus develops in association with the induction of tenascin-C (TNC), a matricellular protein, after aneurysmal subarachnoid…”
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Machine Learning Analysis of Matricellular Proteins and Clinical Variables for Early Prediction of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage
Published in Molecular neurobiology (01-10-2019)“…Although delayed cerebral ischemia (DCI) is a well-known complication after subarachnoid hemorrhage (SAH), there are no reliable biomarkers to predict DCI…”
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10
Deep Brain Stimulation in a Patient with Parkinson's Disease and Cortical Superficial Siderosis
Published in Internal Medicine (01-11-2022)“…Cortical superficial siderosis (cSS) is a rare condition that is regarded as a potential magnetic resonance marker of cerebral amyloid angiopathy (CAA). We…”
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11
Prediction of hematoma expansion in spontaneous intracerebral hemorrhage using a multimodal neural network
Published in Scientific reports (16-07-2024)“…Hematoma expansion occasionally occurs in patients with intracerebral hemorrhage (ICH), associating with poor outcome. Multimodal neural networks incorporating…”
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12
Impacts of lipid-related metabolites, adiposity, and genetic background on blood eosinophil counts: the Nagahama study
Published in Scientific reports (28-07-2021)“…Blood eosinophil count is a useful measure in asthma or COPD management. Recent epidemiological studies revealed that body mass index (BMI) is positively…”
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13
Morphological Characteristics of Neuronal Death After Experimental Subarachnoid Hemorrhage in Mice Using Double Immunoenzymatic Technique
Published in The journal of histochemistry and cytochemistry (01-12-2019)“…Subarachnoid hemorrhage (SAH) is a devastating disease. Neuronal death is an important pathophysiology in the acute phase of SAH, but the histopathological…”
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14
Higher Cerebrospinal Fluid pH may Contribute to the Development of Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage
Published in Translational stroke research (01-04-2017)“…Recent investigations have shown that many factors may cause delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (SAH). To find new…”
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15
Incidence and risk factor of deep venous thrombosis in patients undergoing craniotomy for brain tumors: A Japanese single-center, retrospective study
Published in Thrombosis research (01-05-2018)“…It has been reported that brain tumor resection by craniotomy is a high risk for deep venous thrombosis (DVT), though few data is available in Japanese…”
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Increased Plasma Galectin-3 Preceding the Development of Delayed Cerebral Infarction and Eventual Poor Outcome in Non-Severe Aneurysmal Subarachnoid Hemorrhage
Published in Translational stroke research (01-04-2018)“…A matricellular protein galectin-3 is involved in tissue injury and inflammation, but the role of galectin-3 remains unclear in aneurysmal subarachnoid…”
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17
Evaluation of elevated plasma fatty acids as relevant factors for adult-onset asthma: The Nagahama Study
Published in Allergology International (01-01-2024)“…Obesity and increased body mass index (BMI) are the known risk factors for adult-onset asthma. Serum free fatty acid (FFA) and other blood lipid levels are…”
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Association of lower plasma citric acid with prolonged cough: the Nagahama study
Published in Scientific reports (25-08-2023)“…Little is known about the association of prolonged cough, a common and troublesome symptom, with metabolic pathways. We aimed to clarify this association using…”
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Regnase-1 Maintains Iron Homeostasis via the Degradation of Transferrin Receptor 1 and Prolyl-Hydroxylase-Domain-Containing Protein 3 mRNAs
Published in Cell reports (Cambridge) (23-05-2017)“…Iron metabolism is regulated by transcriptional and post-transcriptional mechanisms. The mRNA of the iron-controlling gene, transferrin receptor 1 (TfR1), has…”
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Dose-Dependent Inhibitory Effects of Cilostazol on Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage
Published in Translational stroke research (01-08-2019)“…Cilostazol is a selective inhibitor of phosphodiesterase type III that downregulates tenascin-C (TNC), a matricellular protein, which may cause delayed…”
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